final review: stuff that seems super testable Flashcards
what are the LABAs and whats the issue
vilanterol, salmeterol
BB warning asthma related death
never use alone
how does cromolyn work? good for acute asthma attack?
works on histamine pathway
NO
T/F ipratropium is used for acute bronchospasm
FALSE
it’s for chronic bronchitis/emphysema
what is the main concerning side effect with ritodrine?
pulmonary edema
T/F Histamine receptor antagonists inhibit the release of histamine, thus reducing its response.
FALSE
Histamine receptor antagonists do NOT inhibit the release of histamine, but rather attach to receptors and prevent the responses mediated by histamine.
if you have second degree adrenocortical insufficiency (cushings) you need to replace with…..?
why
only glucocorticoid
because aldosterone secretion is maintained.
If you have first degree adrenocortical insufficiency, you need to replace with…..?
why
glucocorticoid AND mineralcorticold.
like florinef: fludrocortisone + prednisone
because the adrenals do not secrete cortisol or aldosterone
aldosterone’s effects on:
K
Na
water
increases K excretion
(LOSE K)
increases Na retention
(KEEP Na)
increases water retention, inc blood volume.
aldosterone makes you hang on to salt and water at the expense of K.
GFR —> ___ ____ ____
zona Glomerulosa
zona Fascicula
zona Reticularis
salt, sugar, sex
which synthetic corticosteroids do not have sodium retaining effects?
beta dex tria
betamethasone
dexmethasone
trimincalone
T/F Steriods are approved for a wide list of clinical uses like anti-emetic, asthma, sepsis, post intubation edema….
FALSE. There is no true approval for all those things.
Only approved for: replacement therapy for deficiency states.
what are the biggest offenders of c-diff
1) clinda
2) ancef/keflex
what psych drug carries a BB warning of serious or life threatening psychiatric and behavioral adverse effects
perampanel