Final Review Sheet - 2nd Semester Flashcards
Peptide Hormones
1) chains of 3-200+ amino acids
2) hydrophilic so they mix with blood plasma
Steroid Hormones
1) derived from cholesterol
2) hydrophobic so they must bind to transport proteins in plasma
Monoamines
1) made from the amino acids tryptophan or tyrosine
2) most are hydrophilic
Hormones Mode of Action
- Hormones stimulate only cells that have receptors for them
- Receptor act like switches to turn certain metabolic pathways on or off when the hormone bind to them
Specificity
The receptor for one hormone will not bind other hormones
Saturation
All the receptor molecules are occupied by hormones
Steroid Hormones and TH
a. Hormones diffuse through the plasma membrane and enter nucleus
b. Hormones bind to receptors associated with DNA
c. This activates or inhibits transcription of a gene for metabolic enzymes or other proteins
Peptide
a. Hormones cannot penetrate into a target cell
b. Hormone binds to cell surface receptor, which G protein
c. G protein migrates to effector enzyme and activates it which generates the second messenger
d. The second messenger
Stages of Stress and Adaptation
a. Alarm reaction - norepinephrine from the SNS and epinephrine from the adrenal medulla prepare for flight or fight, body consumes stored glycogen
b. Resistance - glycogen is gone, the body uses cortisol to provide an alternative fuel (fat and protein)
c. Exhaustion - fat reserves are gone, protein meets energy needs
Hormones secreted by the pituitary gland (anterior lobe)
- Follicle-stimulating hormone (FSH)
- Luteinizing hormone (LH)
- Thyroid-stimulating hormone (TSH)
- Adrenocorticotropic hormone (ACTH)
- Prolactin (PRL)
- Growth hormone (GH)
Hormones secreted by the pituitary gland (posterior lobe)
- Antidiuretic hormone (ADH)
2. Oxytocin (OT)
Follicle-stimulating hormone (FSH)
b. Female - stimulates growth of follicle and secretion of estrogen
c. Male - stimulates sperm production
Luteinizing hormone (LH)
b. Female - stimulates ovulation and secretion of progesterone
c. Male - stimulates secretion of testosterone
Thyroid-stimulating hormone (TSH)
b. Stimulates growth of thyroid and secretion of TH
Adrenocorticotropic hormone (ACTH)
b. Stimulates the adrenal cortex to secrete glucocorticoids