Final Review: Renal Regulation of Ions

Question 0

What does the increase in extracellular K+ stimulate?

Answer 0

Increase in aldosterone secretion

Question 1

What is the normal intracellular concentration of K+ ion?

Answer 1

140 mEQ/L

Question 2

Where does reabsorption of K+ ion occur in the kidneys?

Answer 2

Proximal tubule & ascending limb of Henle

Question 3

Where does secretion of K+ occur in the kidneys?

Answer 3

Late tubule and collecting duct

Question 4

What is K+ secretion by principal cells stimulated by?

Answer 4

K+ concentration & aldosterone

Question 5

_______ changes in K+ concentration cause _______ changes in aldosterone secretion by adrenals.

Answer 5

Small

Large

Question 6

What does increased Na+ intake decrease?

Answer 6

Aldosterone, and, therefore, K+ excretion

Question 7

What does increased Na+ increase?

Answer 7

GFR & decreases proximal tubular reabsorption of Na+

Question 8

What situations decrease Ca++ excretion?

Answer 8

Increased PTH levels
Plasma concentration of phosphate
Metabolic acidosis

Question 9

What stimulates uptake of K+ by cells?

Answer 9

Insulin & aldosterone

Question 10

What does Hypokalemia result from and what’s the clinical term for it?

Answer 10

Excess secretion of aldosterone

Conn’s syndrome

Question 11

What does hyperkalemia result from and what’s the clinical name for it?

Answer 11

Deficiency in aldosterone secretion

Addison’s disease

Question 12

How much of the filtered Ca++ is reabsorbed by the kidneys?

Answer 12

Almost all of it