Final Practical Test Flashcards
How do we treat Clostridium perfringens C, A in pigs
Phenoxymethly-penicillin
amoxicillin
tylosin
lincomycin
How to treat Erysipelothrix rhusiopathiae (Swine erysipelas)
Narrow spectrum penicillins and amoxicillin
Streptococcus suis
Narrow spectrum penicillins
amoxicillin
potentiated sulphonamides
lincomycin, florfenicol
swine Staphylococcus hyicus
potentiated sulphonamides
amoxicillin- claculanic acid
tylosin
lincomycin
florfenicol
Actinobacillus pleuropneumoniae, Pasteurella multocida
Amoxicillin
oxytetracycline, doxycycline
potentiated sulphonamides
amoxicilin calvulanic acid
florfenicol
Mycoplasma hyopneumoniae (bronchopneumonia)
oxytetracycline (IM) doxycycline (p.o.)
lincomycin -spectinomycin
florfenicol
macrolides:
tylosin
tilmicrosin
tylvalosin
tulathromycin
gamithromycin
(tildipirosin) (mycoplasma no)
Bordotella bronchiseptica (suis)
Oxtetracycline, doxycycline ad potentiated sulphonamides
Glaesserella parasuis
Oxytetracycline and doxycycline
E. coli in suis
aminoglycosides (neomycin gentamycin, paromomycin apramycin)
colisitn
fluroquinolones
3rd and 4th gen. cephalosporings (cetiofur, cefquinome)
Mycoplasma hyorhinis swine and M. Hyosynoviae
oxtetracycline
doxicycline
tylvalosin
tiamulin
How do we treat Clostridium perfringens C, A in poultry
Phenoxymethly-penicillin (p.o.)
amoxicillin
tylosin
lincomycin
How to treat Erysipelothrix rhusiopathiae in poultry
phenoxymethyl- penicillin
amoxicillin
Staphylococcus aureus poultry
Oxytetracycline, doxycycline
tylosin and linkomycin
Pasteurella multocida in poultry
phenoxymethyl penicilins
amoxicillin
oxitetracycline, doxicycline
tylosin
linkomycin
Ornithobacterium rhinotracheale in poultry
amoxicillin p.o.
oxitetracycline, doxycycline p.o.
tilmicosin p.o.
tiamulin p.o.
Frequent resistance to fluoroquinolones!
Mycoplasma gallisepticum in poultry
M. synoviae
M. meleagridis
oxitetracycline, doxicycline p.o.
tilvalosin p.o.
tiamulin p.o.
Colibacillosis in poultry
not the best
aminoglycosides (neomycin) p.o.
colistin p.o.
enrofloxacin p.o.
Clostridium perfringens, c. difficile
Cattle
phenoxymethylpenicillin p.o. – off label
benzylpenicillin procaine, benzathine im.
amoxicillin p.o., im.
tylosin p.o.
lincomycin p.o., im
Corynebacterium renale (rumm.)
amoxicillin im.
Mastitis caused by Bac. positive and negative. (streptococcus uberis, S. agalctiae (etc.) , S. aureus, E. coli, Klebsiella pneumoniae
P. S. !!!
penicillins, tetracyclines, potentiated SA (IM.)
penicillins, penicillinase resistant penicillins, amoxicillin, tetracyclines, potentiated, SA (IMM.)
BRDC caused by M. Bovis (Pasteurellamultocida, Mannheimia haemolytica,
Histophilussomni, Biebersteinia trehalosi)
oxytetracycline im.
florfenicol sc.
tilmicosin sc.
lincomycin + spectinomycin
Escherichia coli, Salmonella spp. (rumm.) CAlf diarrhea
Symptomatic thereapy, fluid therapy, NSAIDS
Empiric fist choice:
penicillin+streptomycin im.
oxytetracycline im.
potentiated sulfonamides im.
amoxicillin+clavulanic acid im.
gentamicin im., p.o.
anaerobic bacteria rumminants
* * Fusobacterium necrophorum
* Prevotella intermedia
* Porphyromonas levii → interdigitalis dermatitis
* Dichelobacter nodosus → foot rot
oxytetracycline im.
amoxicillin+clavulanic acid im.
lincomycin im.
florfenicol sc.
tulathromycin sc
Strangles in Horses (streptococcis equi. subspe. equi
penicillin im.!
* penicillin+streptomycin im.! – off label
* doxycycline p.o. – off label
* pot. SA p.o. – label
* doxycycline and pot. SA
* For other respiratory diseases too
Rhodococcus equi (pneumonia, enteritis, arthritis)
azithromycin → 10 mg/kg, p.o., SID, for 6 weeks, off label
* clarithromycin → 7.5 mg/kg, p.o., BID, 6 hétig, off label
* gamithromycin → 6-6.6 mg/kg, im., weekly, for 6 weeks, off l.
* All three in combination with: rifampicin (life threatening cases)
Lawsonia intracellularis Horse
doxycycline p.o., off label
Acute necrotic enterocolitis (clostridium perfringes) horse
metronidazol p.o. or per rectum off label
Neonatal sepsis in foals
fliud therapy
NSAIDS+meloxicam+endotoxin
amoxicillin
* amoxicillin + clavulanic acid
* Gentamicin + amoxicillin
* ceftiofur or cefotaxime (+ gentamicin) → BUT → kidney!
* fluoroquinolones → BUT → cartilage!
Arthritis by Staph. Eq.
gentamicin
amikacin → ia. → 125-200 mg/joint
Penicillins
Cefalosporins (ceftiofur)
Aminoglycosides (gentamicin, amikacin)
Tetracyclines (doxycycline)
Macrolides (azithro-, clarithro-, gamithromycin)
Potentiated sulfonamides
Fluoroquinolones
Rifampicin* (AMEG A category)
Metronidazol
Staphylococcus aureus
Staphylococcus pseudintermedius
(S. felis, etc.)
skin and wound infections
Empiric first choices:
amoxicillin + clavulanic acid
cefalexin/cefadroxil
clindamycin (?)
Streptococcus canis (companion animals)
Empiric first choices:
amoxicillin+clavulanic acid
narrow spectrum penicillins!
macrolides, clindamycin (chronic)
florfenicol (ears!)
Otitis externa topical treatment
Staphylococci, streptococci,
Corynebacterium auriscanis
Florfenicol
Aminoglycosides
Polymyxin B?
Fluoroquinolones
Enterococcus faecium, faecalis
-complicated UTI
Resistance to cefalosporins!
Frequently MDR → treatment based on AST! (but
PK should also be considered, e.g. phenicols
Escherichia coli, GI, UTI, septicaemia
UTI:
Empiric first choices:
amoxicillin, amoxicillin + clavulanic acid
potentiated sulfonamides
cefalexin
Prostatitis:
Empiric first choices:
Fluoroquinolones
Potentiated sulfonamides
Septicaemia:
First choices:
amoxicillin + clavulanic acid (iv.)
aminoglycosides (iv.)
3rd generation cefalosporins (iv.)
fluoroquinolones (iv.)
Combinations!
Campylobacter spp.
Easily predicted sensitivity (macrolides, lincosamides)
5. Resistance is common against others (amoxicillin, FQ)
Salmonella spp. Heavy in companion animals
Tetracyclines amoxicillin, P.A.
RARELY treated! (bacteraemia, fever, bloody diarrhea)
swine and small animals B. bronchiseptica
treatment is difficult
Small animals: tetracycline, P.S
Swine: oxytetracycline, doxycycline, P.S
Feline rhinotracheitis complex
Doxycycline,clindamycin, lincospectin
Antiviral treatment! (famciclovir, ganciclovir)
First choices? (see point no. 1!)
Topical treatment for the eye! (active substances?)
P. aeruginosa (. EAR, skin, UTI, airways)
Amikacin, Tobramycin
aminoglycosides
Penicillins, amoxicillin
Tetracyclines
Potentiated sulfonamides
nothing Empirically
B. burgdorferi (lyme disease)
Chronic: Doxycycline, Azithromycin
Acute: Amoxicillin+ clavulanic acid
