Final path lab 3 (messed up & added block stuff in the others) Flashcards
(Female) patient shows up with recurrent pain in the right hypochondriac region. Barium x-ray is done, or endoscopy is done, which shows mass in gallbladder or stomach. Patient says they have a burning sensation during digestion. This is because there are pancreatic enzymes in the stomach. There is no further action that needs to take place. What’s the condition?
Choristoma
(Different organ cells within the tissue)
COMMOLY FOUND IN EYE, GALLBLADDER, STOMACH
Describe the condition?
Choristoma (Gall bladder mucosa with Pancreatic lobules)
Describe the condition
Peutz-Jeghers syndrome
1) Mucocutaneous hyperpigmented lesions that disappear with time
2) gastric hamartomatous polyps
Describe the condition
Pulmonary hamartoma
- coin lesion
- popcorn calcifications
- nodules with hyalin and adipose foci
- most common benign lung tumor
- SOB, minimal respiratory problems & lung nodule
- Biopsy shows mixed pale immature myxomatous tissue
Describe the condition’s features
Pulmonary hamartoma
- coin lesion
- popcorn calcifications
- nodules with hyalin and adipose foci
- most common benign lung tumor
- SOB, minimal respiratory problems & lung nodule
- Biopsy shows mixed pale immature myxomatous tissue
- coin lesion
- popcorn calcifications
- nodules with hyalin and adipose foci
- most common benign lung tumor
- SOB, minimal respiratory problems & lung nodule
- Biopsy shows mixed pale immature myxomatous tissue
Pulmonary hamartoma
1) Mucocutaneous hyperpigmented lesions that disappear with time
2) gastric hamartomatous polyps
peutz-jeghers syndrome
Describe the condition
Hirchsprungs disease
Intraluminal air
Intraluminal air
Hirchsprungs disease
Describe the condition
Necrotizing enterocolitis
1) Hemorrhagic necrosis from submucosa to the muscular wall
2) disintegrated vili
3) air trapped in-between the submucosa (rings)
Describe the condition
Lymphangioma
1) persist
2) due to cystic of cavernous dilation
3) benign malformations of lymphatics
4) can cause testicular atrophy
5) SAME ORGAN CELLS IN THE TISSUE
1) persist
2) due to cystic of cavernous dilation
3) benign malformations of lymphatics
4) can cause testicular atrophy
5) SAME ORGAN CELLS IN THE TISSUE
Lymphangioma
Lymphangioma
1) persist
2) due to cystic of cavernous dilation
3) benign malformations of lymphatics
4) can cause testicular atrophy
5) SAME ORGAN CELLS IN THE TISSUE
Describe the features of Von Hippel Lindau
mutated VHL gene leads to increased risk of
1) Phenochromocytomas
2) renal carcinomas
3) retinal angiomas/hemangioblastomas
4) pancreatic cytadenomas
5) neuroendocrine tumors
mutated VHL gene leads to increased risk of
1) Phenochromocytomas
2) renal carcinomas
3) retinal angiomas/hemangioblastomas
4) pancreatic cytadenomas
5) neuroendocrine tumors
Von Hippel Lindau
Describe the condition
fibroadenoma of the breast
1) small, mobile, encapsulated lump
2) benign adenoma
Describe the condition
fibroadenoma of the breast
1) small, mobile, encapsulated lump
2) benign adenoma
Biopsy shows well circumscribed, uniformly hypercellular stroma, uniform distribution of glands and stroma. The mammogram shows a mass in the breast, that looks fibrous. Can see fibrous capsule covering benign adenoma, why it’s well demarcated.
fibroadenoma of the breast
1) small, mobile, encapsulated lump
2) benign adenoma
Nontender, distorted shape of breast. Well-defined mobile mass. 25 y/o woman comes in and reports a distorted size of one breast.
No risk of developing into breast cancer, but has family Hx of breast cancer
fibroadenoma of the breast
TUMOR GROWS FROM FIBROUS TISSUE
Neonate is presented with nasal flaring and grunting. This is due to surfactant deficiency, therefore need cortisol secretion (need to hit baby and starts crying, release of cortisol increased 🡪 Type II pneumocytes are responsible for secreting surfactant
Neonatal respiratory distress syndrome
Describe the condition
tumor of the breast
1) leaf-like stroma & capsulated by fibrous tissue
Describe the condition
Inflammatory breast cancer
one sided breast enlargement with skin dimpling (peau d’orange)
one sided breast enlargement with skin dimpling (peau d’orange)
Inflammatory breast cancer
Describe the condition
Mature ovarian cystic teratoma (dermatoid cyst)
1) has all 3 germ layers (ecto, endo, meso) skin, sweat glands, etc)
1) has all 3 germ layers (ecto, endo, meso) skin, sweat glands, etc)
Mature ovarian cystic teratoma (dermatoid cyst)
Describe the condition
Mature ovarian cystic teratoma (dermatoid cyst)
1) has all 3 germ layers (ecto, endo, meso) skin, sweat glands, etc)
Describe the condition
Benign leiomyoma
well defined neoplasm
well defined neoplasm
Benign leiomyoma
Describe the grade of A
Normal stratified squamous epithelium
Describe the grade of B
CIN 1
Mild dysplasia
nuclear angulation
Vacuolization
Describe the grade of C
CIN 2
More severe dysplagia (affects more epi layers)
Varied size of cells & nuclei
Superficial layers may look normal
Describe the grade of D
CIN 3
Changes in cell & nuclear size & shape
Abnormal mitoses affective all layers of epi
Describe
Normal cervix
Describe the condition
Cervical cancer
Large, dark & irregular shaped nuclei
Describe the condition
Necrotizing enterocolitis
1) hemorrhagic necrosis from submucosa to muscular wall
2) abdominal distension
3) bloody stools
4) AIR INBETWEEN THE SUBMUCOSA (RINGS)
5) Disintegrated villi
1) hemorrhagic necrosis from submucosa to muscular wall
2) abdominal distension
3) bloody stools
4) AIR INBETWEEN THE SUBMUCOSA (RINGS)
5) Disintegrated villi
Necrotizing enterocolitis
Describe the condition
Hirschsprung’s
1) Intraluminal air
2) Hyperactive response to bacteria increasing TLR’s
3) Mass in duodenal area
1) Intraluminal air
2) Hyperactive response to bacteria increasing TLR’s
3) Mass in duodenal area
Hirschsprung’s
1) leaf-like stroma & capsulated by fibrous tissue
Phyllodes tumor of the breast
Describe the condition
Neonatal Respiratory Distress syndrome
1) Eosinophilic hyalin lining the bronchioles, alveolar ducts, & alveoli (necrotic type 2 pneumocytes & fibrin)
2) increase pulmonary vascular permeability
3) leaking plasma into hyaline
4) decreased surfactant
5) GROUND GLASS OPACITIES
1) Eosinophilic hyalin lining the bronchioles, alveolar ducts, & alveoli (necrotic type 2 pneumocytes & fibrin)
2) increase pulmonary vascular permeability
3) leaking plasma into hyaline
4) decreased surfactant
5) GROUND GLASS OPACITIES
neonatalrespiratory distress syndrome
Describe the condition
Capillary hemangioma
1) Disappear by age 6
2) No stroma in-between BV
3) Face, neck, chest, butt
4) decreased vision (amblyopia) & droopy eye
1) Disappear by age 6
2) No stroma in-between BV
3) Face, neck, chest, butt
4) decreased vision (amblyopia) & droopy eye
Capillary hemangioma
Describe the features of hemangiomas
Dilated vascular channels filled with alot of RBCs
Describe the condition
Cavernous hemangioma
1) Persist
2) STROMA inbetween BV
3) Brain & liver
4) neurodeficits, seizures, speech & memory loss
5) remove with surgery
1) Persist
2) STROMA inbetween BV
3) Brain & liver
4) neurodeficits, seizures, speech & memory loss
5) remove with surgery
Cavernous hemangioma
