Final- Lymphatic, Immune, Digestive, Urinary, and Reproductive Systems system Flashcards
What are the 4 components of the lymphatic system?
1) lymphatic vessels
2) lymphoid tissues
3) lymphoid organs
4) immune system
What are the lymphoid vessels in order from smallest to largest?
test q
1) capillaries
2) collecting vessels
3) trunks (regional)
3A) jugular
3B) subclavian
3C) broncho-mediastinal
3D) lumbar (R/L)
3E) intestinal
4) ducts (right lymphatic and left thoracic duct)
Cisterna chyli (“bowl of juice”) is at the same level of L2, and receives lymph fluid from….
test q
Lumbar and intestinal trunks
What does the right lymphatic duct drain?
Exam question
Lymph from the right half of head, right side of thorax, and right arm into the right subclavian vein
What does the left thoracic duct drain?
Exam q
Lymph from everything besides R half of head, R side of thorax, and R arm into the L subclavian vein
What is another name for lymphoid tissues?
Lymphoid nodules (follicles)
_____________________ are encapsulated bundles of lymphatic cells with lamina propria (CT) layer of mucous membranes
Lymphoid tissues
Where are lymphoid tissues found (think tracts and tissues)?
GI, respiratory, reproductive, and urinary tracts, and peyer’s patches of the SI
What are the lymphatic organs?
-BM
-lymph nodes
-thymus
-spleen
-liver
-tonsils
Within BM, there is hematopoietic stem cells (blood cell precursors) that produce _____________ which mature into B and T lymphocytes
test q
Lymphoblasts
What serves as lymph filters and activates the immune system to remove and destroy pathogens/debris?
test q
Lymph nodes
What are the 4 parts of a lymph node structurally?
test q
1) cortex
2) medulla
3) afferent lymph vessels
4) efferent lymph vessels
What portion of the lymph node is the outer portion that contains WBCs, dendritic cells, and B cells predominantly?
test q
Cortex
What portion of the lymph node is the inner portion that contains large lymph capillaries?
test q
Medulla
What vessel within the lymph node takes lymph fluid to the lymph node?
test q
Afferent lymph vessels
What vessel within the lymph node takes lymph fluid away from lymph nodes?
test q
Efferent lymph vessels
Which lymphoid organ is located deep to the manubrium of the sternum?
test q
Thymus
Which lymphoid organ is bilobed and undergoes involution with age (gets smaller and replaces by fat)?
test q
Thymus
Which lymphoid organ has thymocytes (immature T lymphocytes) that migrate here from BM?
test q
Thymus
Which lymphoid organ secretes thymic hormones to stimulate maturation of thymocytes to mature T cells (T lymphocytes)?
test q
Thymus
Where is the site of lymphatic proliferation?
test q
Spleen
Which lymphoid organ has immune surveillance and response?
test q
Spleen
Which lymphoid organ extracts aged RBCs and platelets to break them down?
Test q
Spleen
What are the immune functions of the liver?
test q
Remove pathogens and toxins entering the body via the GI tract (taken to liver by the portal system)
Which lymphoid organ is the major producer of anti-microbial proteins (complement proteins) for immune system responses?
test q
Liver
Which lymphoid organ is in the pharynx behind the nasal and oral cavities, and has crypts that trap microbes (pathogenic microorganisms)?
test q
Tonsils
What are the 4 paired tonsils?
test q
1) pharyngeal (also called adenoid, found behind nasopharynx)
2) tubal (near opening of Eustachian (auditory) tube in nasopharynx)
3) palatine (below soft palate)
4) lingual (behind tongue)
What is the difference between the lymphatic system and immune system?
Lymphatic system= consists of lymphatic vessels, tissues, and organs and the immune subsystem provides surveillance and defense against pathogens and foreign substances
Immune system= defense subsystem of lymphatic system comprised of chemicals, anti-microbial proteins and WBCs that protect against disease
What are the subsystems of the immune system?
Innate (nonspecific) and acquired (specific/adaptive)
What is the first line of defense of the innate (nonspecific) immune system?
test q
surface barriers (skin and mucous membranes)
What is the 2nd line of defense of the innate (nonspecific) immune system?
test q
internal defenses (chemicals, anti-microbial proteins, and cells)
Which immune system recognizes and responds to pathogens in a generic way and may cause fever and inflammation?
innate immune system
Which immune system has no memory or long term immunity?
innate immune system
What is the 3rd line of defense?
test q
adaptive/acquired/specific immune system
-proteins (cytokines and complement proteins) and cells
-humoral (antibody-mediated immunity w/ B cells
-cellular (cell mediated) immunity with T cells
-recognize and respond to pathogens
-has memory and long term immunity (recognize subsequent infections)
-exists for years to life
B cells are also known as B lymphocytes and are a part of humoral (antibody-mediated) immunity. What do B cells produce and where are they derived from?
test q
B cells produce antibodies (Y shaped proteins that bind to microbes thereby disabling or killing them)
B cells are derived from lymphoblast cells in BM and mature there
T cells are also known as T lymphocytes and are a part of cell mediated immunity. What do they do and where are they derived from?
test q
T cells directly bind to microbes and perferate the cell membrane and injects enzymes to destroy them
T cells are derived from lymphoblast cells in BM, and migrate to mature in the thymus gland
What are the 4 layers of the digestive tract?
test q
1) serosa or adventita (outer layer of serous membrane/CT)
2)) muscularis externa
3) submucosa (CT containing blood lymph, and nerve fibers)
4) mucosa
How many layers is the muscularis externa?
test q
2 layers of smooth muscle (outer layer is longitudinal and the inner layer is circular)
The submucosa is a CT containing what?
test q
blood, lymph, and nerve fibers
What is the innermost epithelial lining of the digestive system?
test q
mucosa
What layer of the digestive system secretes mucus, absorbs nutrients, and protects against infection with lymphoid follicles?
test q
mucosa
The esophageal sphincter is made up of a smooth muscle ring that is voluntary or involuntary? Where is it located and what does it do?
test q
involuntary
located between the diaphragm, where esophagus meets the stomach
prevents reflux of stomach contents
What are the 4 parts of the stomach?
1) cardia
2) fundus
3) body
3) pylorus
What is the mucosa of the stomach called?
Gastric mucosa (mucous membrane)
What organ/region has folds/rugae, gastric pits, and glands, and is made up of simple columnar epithelium, lamina propria, and muscularis mucosae?
Mucosa of the stomach
What is another name for rugae?
Gastric folds
What are rugae and what does it allow?
Longitudinal wrinkles in gastric mucosa that allows for expansion of stomach
What are gastric pits? What do they contain?
test q
Indentations in the gastric mucosa that contains entrances to 3-5 gastric glands and is lined with surface mucous cells
Where are gastric glands (cells) found and what do they secrete?
test q
Found in gastric pits (lamina propria) and open into bases of gastric pits
Secretes HCl, digestive enzymes, and gastric hormones
What are the 3 parts of the small intestine?
test q
-duodenum
-jejunum
-ileum
What part of the small intestine surrounds the head of the pancreas?
Exam q
Duodenum
What part of the small intestine does most of the chemical digestion?
Test q
Duodenum
What is the shortest section of the small intestine (8 feet)?
test q
Jejunum
What section of the small intestine does the most absorption?
Test q
Jejunum
What section of the small intestine is the longest (12 feet)?
test q
Ileum
What section of the small intestine joins the large intestine at the ileocecal valve?
test q
Ileum
What is found within the mucosa of the small intestine?
-pilcae circulares
-villi
-mucosal cells (enterocytes)
-microvilli (brush border)
-crypts of Lieberkuhn
What are plicae circulares? Where is it found and what does it do?
test q
Circular folds (valvulae conniventes/valves of Kerkring) of the mucosa of small intestine
Mostly found in lower duodenum and jejunum
Increases SA for absorption
What are villi and what do they allow for?
test q
Finger like extensions of mucosa on surface of plicae and further increase SA for absorption
What are mucosal cells? Where are they found and what do they do?
Also called enterocytes
Found on the surface of villi and line the lumen of SI
Absorb nutrients
What are microvilli (“brush border”) of the SI and what does it do?
test q
Tiny projections of plasma membrane of mucosal cells and increases SA of plasma membrane
What are crypts of Lieberkuhn?
test q
Vaults or pits between villi, lined by intestinal glands/cells
What are the 4 subdivisions of the large intestine?
test q
1) cecum
2) colon
3) rectum (in pelvis)
4) anus (in pelvis)
What are the features of the large intestine?
test q
-epiploic appendages (small fat filled appendages of visceral peritoneum)
-taeniae coli (muscularis externa reduced to 3 bands/ribbons)
-haustra (pocket like sacs, giving segmented appearance)
-Plicae semilunares (half moon shaped folds of colon walls formed by contraction)
What are epiploic appendages?
test q
Small fat filled appendages of visceral peritoneum in the large intestine
What are taeniae coli?
test q
Muscularis externa reduced to 3 bands/ribbons in the large intestine
What are haustra?
test q
Pocket like sacs giving segmental appearance in the large intestine
What are plicae semilunares?
test q
Half moon shaped folds of colon walls formed by contraction of the large intestine
What is the first part of the large intestine and is a blind pouch?
test q
Cecum
What quadrant is the cecum of the large intestine found in?
test q
RLQ
The appendix arises from the….
test q
Posteriomedial aspect of the cecum
The appendix is inferior to the….
test q
Ileocecal junction
What are the 4 parts of the colon?
test q
1) ascending colon
2) transverse colon
3) descending colon
4) sigmoid colon
What are the 2 flexures of the colon (large intestine)?
test q
-R colic flexure/hepatic flexure
-L colic flexure/splenic flexure
Where is the R colic flexure/hepatic flexure located?
test q
RUQ below liver, sharp bend between the ascending and transverse colon
Where is the L colic flexure/splenic flexure located?
test q
LUQ below spleen, sharp bend between transverse and descending colon
What are the accessory organs of the duodenum?
Exam question
Liver, gallbladder, and pancreas
Which accessory organ of the duodenum has the largest gland?
test q
The liver
Which accessory organ of the duodenum is in the RUQ, produces bile, receives nutrients from the GI tract except long chain fatty acids and cholesterol, and detoxifies blood?
test q
The liver
Who produces bile?
test q
Liver
What are the 4 lobes of the liver?
1) right
2) left
3) quadrate
4) caudal lobe
What is known as the port of the liver?
Porta hepatis
________________ is a deep fissure in the inferior surface of the liver and between the quadrate and caudate lobes
Porta hepatis
All blood vessels (except hepatic veins), nerves, and hepatic ducts (R and L) enter or leave the liver through here
Porta hepatis
What is the structural unit of the liver (hexagon shaped)?
Lobule (liver acinus)
What is composed of hepatocytes (liver cells) that produce bile (breaks down fats)?
Lobule (liver acinus)
What is the storage sac for bile?
test q
Gallbladder
What are the 3 parts of the gallbladder?
Fundus (head), body, and neck
What shape is the pancreas?
test q
Tadpole shaped
The pancreas is located primarily behind the….
test q
Stomach
The head of the pancreas is encircled by the…
test q
Duodenum
The tail of the pancreas abuts the…
test q
spleen
Does the pancreas have endocrine or exocrine functions? Or both
Both
What are the 4 exocrine functions of the pancreas?
1) carbohydrates (pancreatic amylase)
2) fats (pancreatic lipase)
3) proteins (pancreatic proteases- trypsin and chymotrypsin)
4) nucleic acids (pancreatic nucleases)
What are the endocrine functions of the pancreas?
Islets of langerhans (produce hormones) which consist of different cell types- alpha, beta, and delta cells
What are alpha cells? What do they do?
test q
Glucagon
-increase blood sugar (glycogenolysis and gluconeogenesis)
What are beta cells and what do they do?
test q
Insulin
-decrease blood sugar (enhance membrane transport of glucose into cells to glycogenesis, protein synthesis, and fat synthesis)
What are delta cells and what do they do?
test q
Somatostatin
-decrease GH secretion and all other hormones from the pancreas
In the hepatopancreatic duct system, the bile duct carries bile produced in the liver and stored in the gallbladder and unites with the pancreatic duct which carries digestive enzymes produced by the pancreas and empties these substances into the _______________ for chemical digestion
test q
duodenum
What is the hepato-pancreatic duct system?
test q
-bile from the liver and gallbladder mix with enzymes from the pancreas
-enter descending part of the duodenum
-reason that most chemical digestion occurs in the duodenum
The kidneys are surrounded by CT and fat and protected posteriorly by back muscles and….
Floating ribs 11 and 12