Final-Lecture Flashcards
Important toxin in Pseudomonas?
T3 Secretion Exotoxin A
What does Exotoxin A do for pseudomonas
Inhibits protein synthesis
What does pseudomonas cause in dogs and cats?
Otitis externa, UTI, (pyoderma)
What does pseudomonas cause in horses?
Metritis, Keratitis, Conjunctivitis
What species is very susceptible to pseudomonas?
Farmed mink
What does pseudomonas cause in cows?
Mastitis
Bacteria that can cause botromycosis?
Pseudomonas and Staphylococcus
Fleece rot of sheep?
Pseudomonas
What is important to remember about Burkholderia?
Biosafety level 3! REPORT
Causative agent of Glanders?
Burkholderia mallei
Secretion system of Burkholderia?
T3 and T4
Reservoir of b. mallei?
Horses
Cutaneous glanders?
Farcy (B. mallei)
Symptoms of glanders?
fever, nasal discharge, lymphadenitit. Chronic form will also have Farcy
Causative agent of Melioidosis?
B. pseudomallei
Alternative name for Melioidosis in horses?
Pseudoglanders
The great imitator?
B. pseudomallei
Infective agent of B. pseudomallei
saprophyte
Differentiating lab characteristic between the two Burkholderias?
Pseudomallei-Motile
Mallei-Non motile
Is Burkholderia zoonotic?
Yes! Both
Symptoms of Melioidosis?
systemic, chronic nodular, purulent, pyogranulomatous
Melioidosis in humans?
Whittier’s Disease, Vietnamese time bomb
What does. B. pseudomallei cause in equine?
Pseudoglanders
Official test for Burkholderia in horses?
Complement fixation
Does Burkholderia have lifelong immunity?
No!
Treatment of Bukrholderia in equine?
Kill!!!
Contagious Equine Metitis?
Taylorella equigenitalis
Country with T. equigenitalis?
Europe
Transmission of T. equigenitalis?
STI
Only sign of T. equigenitalis?
Failure to conceive
Infectious Bovine Keratoconjunctivitis
Moraxella Bovis
most common ocular disease in cattle?
M. bovis
Virulence factors for M. bovis?
Cytotoxin and Fimbriae
Difference with Moraxella LPS?
No O-repeat
M. bovis toxin?
Mbx
What does Mbx do?
pore forming
Pink eye?
M. bovis
New forest disease?
M. bovis
Age group predisposed to M. bovis?
Under 2y
Porcine atrophic rhinitis
B. bronchiseptica, P. multocida
Canine kennel cough?
B. bronchiseptica
Turkey Coryza?
B. avium
Adhesion that allows for attachment of Bordatella?
BvsAS
Virulence factor in Bordatella that leads to hemagglutination?
FHA
Virulence factor in Bordatella leading to damage of epithelial cells releasing IL-1
Tracheal cytotoxin
Virulence factor in Bordatella that inhibits osteoblast differentiation in atrophic rhinitis?
Dermonecrotic toxin
Pore forming toxin in Bordatella?
Adenylyl cyclase toxin
Toxin in Bordatella leading to loss of fluids?
Pertussis toxin
Type of vaccine for Bordatella?
Live attenuated
Agar for francisella?
Glucose-Cysteine Blood
Francisella in most animals?
tularensis
Francisella in fish?
noatunensis
Franciscella in NA?
tularensis tularensis
Francisella in Europe?
tularensis holarctica
Important receptor in Francisella capsule?
Mannose-for phagocytosis
Francisella factor that suppresses respiratory burst?
Acp
Vector of Francisella?
Dermacentor and Amblyomma
Most affected domestic animal for Francisella?
Cats
Most common form of Francisella?
Ulceroglandular
Liver lesions for Francisella can be confused with what other bacteria?
TB
Immune response to francisella?
CMI
What agar does Francisella not grow on?
MacConkey
What fish are affected by Francisella
warm, cold, marine, fresh
Growing conditions for francisella?
20-30C
What is unique about brucella’s capsule?
No capsule
No flagella
No spores
What organ systems does brucella affect?
Reticuloendothelial system
Genital tract
What is the main symptom for brucella?
Abortion
Brucella in sheep and goats?
B. melitensis
Brucella in cows and humans?
B. abortus
Brucella in swine?
B. suis
Transmission of brucella?
Ingestion
Transmission of brucella in dogs?
Urine