Final-Lecture Flashcards
Important toxin in Pseudomonas?
T3 Secretion Exotoxin A
What does Exotoxin A do for pseudomonas
Inhibits protein synthesis
What does pseudomonas cause in dogs and cats?
Otitis externa, UTI, (pyoderma)
What does pseudomonas cause in horses?
Metritis, Keratitis, Conjunctivitis
What species is very susceptible to pseudomonas?
Farmed mink
What does pseudomonas cause in cows?
Mastitis
Bacteria that can cause botromycosis?
Pseudomonas and Staphylococcus
Fleece rot of sheep?
Pseudomonas
What is important to remember about Burkholderia?
Biosafety level 3! REPORT
Causative agent of Glanders?
Burkholderia mallei
Secretion system of Burkholderia?
T3 and T4
Reservoir of b. mallei?
Horses
Cutaneous glanders?
Farcy (B. mallei)
Symptoms of glanders?
fever, nasal discharge, lymphadenitit. Chronic form will also have Farcy
Causative agent of Melioidosis?
B. pseudomallei
Alternative name for Melioidosis in horses?
Pseudoglanders
The great imitator?
B. pseudomallei
Infective agent of B. pseudomallei
saprophyte
Differentiating lab characteristic between the two Burkholderias?
Pseudomallei-Motile
Mallei-Non motile
Is Burkholderia zoonotic?
Yes! Both
Symptoms of Melioidosis?
systemic, chronic nodular, purulent, pyogranulomatous
Melioidosis in humans?
Whittier’s Disease, Vietnamese time bomb
What does. B. pseudomallei cause in equine?
Pseudoglanders
Official test for Burkholderia in horses?
Complement fixation
Does Burkholderia have lifelong immunity?
No!
Treatment of Bukrholderia in equine?
Kill!!!
Contagious Equine Metitis?
Taylorella equigenitalis
Country with T. equigenitalis?
Europe
Transmission of T. equigenitalis?
STI
Only sign of T. equigenitalis?
Failure to conceive
Infectious Bovine Keratoconjunctivitis
Moraxella Bovis
most common ocular disease in cattle?
M. bovis
Virulence factors for M. bovis?
Cytotoxin and Fimbriae
Difference with Moraxella LPS?
No O-repeat
M. bovis toxin?
Mbx
What does Mbx do?
pore forming
Pink eye?
M. bovis
New forest disease?
M. bovis
Age group predisposed to M. bovis?
Under 2y
Porcine atrophic rhinitis
B. bronchiseptica, P. multocida
Canine kennel cough?
B. bronchiseptica
Turkey Coryza?
B. avium
Adhesion that allows for attachment of Bordatella?
BvsAS
Virulence factor in Bordatella that leads to hemagglutination?
FHA
Virulence factor in Bordatella leading to damage of epithelial cells releasing IL-1
Tracheal cytotoxin
Virulence factor in Bordatella that inhibits osteoblast differentiation in atrophic rhinitis?
Dermonecrotic toxin
Pore forming toxin in Bordatella?
Adenylyl cyclase toxin
Toxin in Bordatella leading to loss of fluids?
Pertussis toxin
Type of vaccine for Bordatella?
Live attenuated
Agar for francisella?
Glucose-Cysteine Blood
Francisella in most animals?
tularensis
Francisella in fish?
noatunensis
Franciscella in NA?
tularensis tularensis
Francisella in Europe?
tularensis holarctica
Important receptor in Francisella capsule?
Mannose-for phagocytosis
Francisella factor that suppresses respiratory burst?
Acp
Vector of Francisella?
Dermacentor and Amblyomma
Most affected domestic animal for Francisella?
Cats
Most common form of Francisella?
Ulceroglandular
Liver lesions for Francisella can be confused with what other bacteria?
TB
Immune response to francisella?
CMI
What agar does Francisella not grow on?
MacConkey
What fish are affected by Francisella
warm, cold, marine, fresh
Growing conditions for francisella?
20-30C
What is unique about brucella’s capsule?
No capsule
No flagella
No spores
What organ systems does brucella affect?
Reticuloendothelial system
Genital tract
What is the main symptom for brucella?
Abortion
Brucella in sheep and goats?
B. melitensis
Brucella in cows and humans?
B. abortus
Brucella in swine?
B. suis
Transmission of brucella?
Ingestion
Transmission of brucella in dogs?
Urine
What cell does Brucella infect?
Macrophages
What does Brucella cause in cattle other than genital issues?
Hygromas
What does Brucella cause in horses other than genital issues?
Poll evil
What does Brucella cause in humans other than genital issues?
Undulant/Malta Fever
Brucella cattle vaccine that required two doses?
B. abortus 45/20
Brucella cattle vaccine that only requires one dose?
B abortus 19 and RB51
Treatment for brucella in livestock?
None
Treatment for brucella in dogs?
Neuter and antibiotics
Gull wing bacteria shape?
Campylobacter
What organ systems does Campylobacter affect?
Reproductive
Intestinal
Leading cause of human food poisoning?
C. jejuni, C. coli
Which campylobacter has LOS?
C. jejuni
Adhesin for C. jejuni and C. coli?
CadF
Important toxin in Campylobacter?
Cytolethal Distending Toxin
Reservoir for C. fetus venerealis?
preputial crypts, vagina
Reservoir for C. fetus fetus?
Intestine, gall bladder (ruminants)
Reservoir for C. jejuni?
Intestine, gall bladder
Which campylobacter is transmitted by ingestion?
C. fetus fetus, C. jejuni jejuni
Transmission of C. fetus venerealis
Venereal
Pathognomic for campylobacter (jejuni or fetus fetus)?
Donut shaped liver lesions
Growth differences between Arcobacter and Campylobacter?
A is aerotolerant
A grows at lower temps
A grows on MacConkey
Swine dysentery?
Bracyspira hyodysenteriae
Which Brachyspira is very hemolytic?
B. hyodysenteriae (ring phenomenon)
What part of the GIT does Bracyspira affect?
Colon
Proliferative Enteropathy?
Lawsonia intracellularis
Vent disease of rabbits, Rabbit syphilis?
Treponema paraluiscuiculi
Important enzyme in Helicobacter?
Urease- neutralizes gastric acid
Important toxin in Helicobacter?
Cytolethal Distending Toxin (like C. jejuni)
Where is the reservoir for Helicobacter?
Gastric mucus layer
What does Helicobacter cause?
Chronic inflammation
Hallmark symptom for Lepto?
late term abortion
What does Lepto cause in horses?
Moon Blindness
Recurrent Uveitis
Where is the reservoir for Lepto?
Kidney Tubules (rodents)
How is Lepto transmitted?
Bodies of water
Most important serovar for Lepto in dogs?
Grippotyphosa
What form of canine lepto will not have icterus?
Acute
What is the most common form of canine lepto?
Uremic form
Most common serovars in bovine lepto?
Hardjo, Pomona
Which serovar of lepto causes weak calf syndrome?
Hardjo
Most common swine serovar for lepto?
Pomona
Which species is very resistant to lepto?
Cats
Which serovar of lepto causes fatal liver or renal disease in humans?
Icterohemorrhagiae
What is the most common way to diagnose Lepto?
Serology
What can develop in cattle with persistent Lepto?
biofilm
Fowl spirochetosis?
Borrelia anserina
Lyme disease?
Borrelia burgdorferi
Vector of Borrelia?
Ticks
What species is most commonly afed by B. anserina?
Chickens
What tick transmits B. anserina?
Argas
What does B. theileri cause in cattle?
Mild febrile anemia
Where is B. theileri?
Africa, Australia
Lyme disease in NA?
B. burgdorferi sensu stricto
Tick vector for Lyme?
Ixodes
What does lyme disease cause in dogs?
Polyarthritis, fever, anorexia
What species is uncommonly affected by Lyme?
Cats
What is distinct about Mollicutes form?
No cell wall!
Which type of mollicutes cause anemia?
Hemotrophic
Which type of mollicutes cause RT, UT infections?
Non-Hemotrophic
What helps Mollicutes have osmotic stability with no cell wall?
Cholesterol
What are the mollicutes?
Mycoplasma, Ureaplasma
Reservoir of mollicutes?
Mucosal surfaces
Infectious sinusitis in turkeys?
Mycoplasma gallisepticum
What does M. gallisepticum cause?
Respiratory disease
Contagious bovine pleuropneumonia?
Mycoplasma mycoides mycoides
Which colony virulent causes contagious bovine pleuropneumonia?
Small Colony Variant
Most common Mycoplasma in cows?
M. mycoides mycoides
Mycoplasma mastitis?
M. bovis
Contagious caprine pleuropneumoniae?
M. capicolum capripneumoniae
Contagious agalctia of sheep and goats?
M. agalactiae, M. putrefaciens
Porcine enzootic pneumonia?
M. hyopneumoniae
Porcine polyserositis?
M. hyorhinis
Most common way to diagnose Mycoplasma?
Sero and Molec
Feline infectious anemia?
M. haemolfelis
Infective form of Chlamydia?
Elementary body
Metabolically active form of Chlamydia?
Reticulate body
Which Chlamydia are zoonotic?
C. abortus
C. felis
C. pneumoniae
What species does C. abortus affect?
Sheep, goats, cattle
What species does C. pneumoniae affect?
Horses, dogs
What Chylamydia has a carrier state?
C. abortus
What does C. felis cause?
conjunctivitis, rhinitis, pneumonitis
Ricketssiales that survives in RBCs, phagocytes, platelets?
Anaplasma
Ricketssiales that survives in phagocytic cells?
Ehrlichia
Ricketssiales that survives in MO?
Neorikettsia
Ricketssiales that survives in vascular epithelium?
Rickettsiae
Anaplasma found on the periphery of RBCs?
Anaplasma marginale
Anaplasma found in dog’s platelets?
A. platys
Anaplasma found in NOs of dogs, horses and humans?
A. phagocytophilum
Vector of A. marginale?
Boophilus
Anaplasma affecting ruminants?
A. marginale
Stain for Anaplasma?
GIEMSA
Tick borne fever?
A. phagocytophilum
Reservoir for A. phagocytophilum?
Rodents, mice, deer
Vector of A. phagocytophilum?
Ixodes
What part of the blood cell does A. phagocytophilum?
WITHIN neutrophils
Infectious canine cyclic thrombocytopenia?
Anaplasma platys
Rocky mountain spotted fever?
Rickettsia rickettsii
Vector of Ricketssia?
Dermacentor
Reservoir of Ricketssia?
Small animals
Ricketsialles that can be transmitted by air?
Coxiella burnetii
Bioweapon Ricketsialles?
Coxiella burnetti
Canine monocytic ehrlichiosis?
e. canis
Vector of ehrlichia?
Rhipicephalus sanguineus
African heartwater?
E. ruminatum
Where is African heartwater other than Africa?
Carib
Vector of African heartwater?
Amblyomma
Hallmark sign of african heartwater?
Pericardial effusion
Salmon poisoning disease is caused by what?
Neorickettsia helminthoeca
Elokomin fluke fever?
mild form of Neorickettsia helminthoeca
Potomac horse fever?
Neorickettsia
Vector of Aegyptianellosis?
Argus
