Final-Infections During Pregnancy Flashcards
Bartholin’s cyst
Blockage of bartholin’s gland due to congenital stenosis, thickened mucous at the outlet, mechanical trauma, neoplasm
-When fluid is infected an abcess will form
What should you expect if bartholin’s cysts are present bilaterally?
GC
DDx bartholin’s cyst
cyst, abcess, neoplasm, STI, sebaceous cyst
Management of bartholin’s cyst
- small asx = no tx
- draining abcess: culture and r/o STI and treat
- CBC if extended inflammation
- Uninfected bartholin’s cyst postpone tx in preg
- Refer to OB if rapid enlargement, increasing pain, abcess formation, hemorrhage into the cyst
Bartholin’s cyst tx
- sitz baths
- broad spectrum antibiotics
- surgical procedures
- excision (only recommended w/ a huge abcess, multiocular or recurrent abcess)
ND tx of bartholin’s cyst
- sitz baths w/ drawing herbs (echinacea, clay, charcoal)
- drawing poultice
- Hp hepar sulph to help ripen abcess
- NO GOLDENSEAL
- Iummune support
PID
Infxn of uterus, fallopia tube and adjacent pelvic structures not associated with pregnancy or abdominal surgery
Organisms associated with PID
Upper genital tract: usu GC or CT
G. vaginialis, H. influenzae, enteric gram- rods, strep agalactiae, CMV, mycoplasma hominis, urea urealyticum
Ssx PID
Variable, can include:
- lower abd pain
- adnexal tenderness
- Chandelier’s sign
- Fever
- purulent vaginal d/c
- possible palpable mass
Most serious complication of PID
TOA (Tubo-ovarian abcess)
PID complications
- hydrosalpinx
- TOA
- poor pregnancy outcome
- infant pneumonia
- neonatal death
- infertility
- chronic pelvic pain
- ectopic preg
- Increased risk of CA of reproductive tract
- Vulnerability to HIV
Predisposing factors to PID
- trichomonas
- douching
- STI exposure
- lower socioeconomic group
- no use of contraception
- multiple sex partners
- PID hx
- IUD use
- cigarette smoking
- sexual activity at a young age
- invasive genital medical procedures
- adolescence
PID dx
- clinical sxs and culture confirmed w/ rapid improvement w/ abx therapy
- wet prep >30 WBC/hpf
- elevated ESR, CRP
- endometritis w/ endometrial biopsy
- US or other imaging showing fluid-filled, thickened tubes, TOA, free pelvic fluid or laparoscopic evidence
Gold standard for PID dx
Laparoscopy
PID ddx
- ectopic preg
- endometritis
- ovarian cysts
- cancer
- myoma
- appendicitis
- pancreatitis
- septic abortion
- acute cholecystitis
- GC vs. nongonorrheal PID
- Mesenteric lymphadenitis
PID during pregnancy
High risk for maternal morbidity, fetal wastage, preterm delivery
HIV and PID
HIV + woman will respond to antibiotics but may have a more severe dz course and more likely to require surgical tx
PID management
- Pt education
- Hx, LMP, pregnancy
- Cultures and wet mount
- Tx sexual partners if sexual contact w/ woman within 60 days of sxs
- Instruct woman to complete tx
- Surgical tx
Toxoplasmosis sources
- cats who have eaten infected birds or rodents who have contacted the feces of infected cats
- humans can contract it from dirty sandboxes or playgrounds where cats have left feces
- raw meat of inadequately cooked esp pork or mutton
- water contaminated by cat feces
- milk from infected animals
- organ transplants or transfusions
Toxoplasmosis sxs
- usu subclinical
2. rash, lymphadenopathy, fever, malaise, generally mildly sick, can be similar to mono
Toxoplasmosis dx
- elevated IgG = past infxn
- elevated IgM = current or recent infxn
- infant: rising IgG titers
Toxoplasmosis tx
Toxic antimicrobials –> cannot use in preg
Toxoplasmosis prevention
- Avoid cat feces
- Cook meat well
- Wash hands after handling raw meat and cats
- Avoid raw milk and eggs
Rubella sxs
Fine rash, posterior cervical or occipital lymph node enlargement, malaise, mild fever
Rubella dx
Rubella titer (elevated IgM = current or recent exposure)
Rubella risk to fetus
- Malformations: deafness, cardiac defects, cataracts
- Congenital rubella syndrome: low birth weight, bone marrow damage, hepatitis, myocarditis, pneumonitis, encephalitis, chromosomal abnormalities
- at 1-8 wks PG, 40-80% risk fetal defects
- 9-12 wks, 20% risk
- 13-16 wks 5% risk
- 17-20 wks, 1% risk
Rubella management
- consider TAB in 1st and 2nd trimesters
2. Immunize non-immune women immediately after delivery
CMV Transmission
Transplacentally, from cervix, from breast milk
CMV Risk to Infant
- Subclinical and mild maternal infxn: jaundic, petechiae, feeding difficulty, irritability, muscle weakness, hepatosplenomegaly
- Maternal severe infxn: SGA, microcephaly, meningoencephalitis, chorioretinits, mental retardation