Final Flashcards
What embryonic layer is the neural plate a thickening of?
Ectoderm
What is formed after the neural plate and then after that intermediate?
Neural plate - neural groove - neural tube
What are the primary vesicles in the 3 week embryo?
Prosencephalon
Mesencephalon
Rhombencephalon
What are the secondary brain vesicles that form from the primary vesicles?
Telencephalon
Diencephalon
Mesencephalon
Metencehpalon
Myelencephalon
What are the 4 major brain regions?
Cerebrum
Diencephalon
Brain stem
Cerebellum
What 2 structures are included in the diencephalon?
Thalamus
Hypothalamus
What 3 structures make up the brain stem?
Mesencephalon
Pons
Medulla oblongata
Gray matter forms ___ whereas white matter forms ___
Nuclei; tracts
What structures protect the brain? 4
Cranium
Meninges
CSF
BBB
What is the function of the cranial meninges?
Protect the brain
Framework for blood vessels
Circulate CSF
Is the epidural space of the skull a real space?
No, it is a potential space existing under pathological conditions
Is the subdural space a real space?
No, potential space only existing under pathological conditions
What does the subarachnoid space contain? 3
Actual space containing CSF, arteries, and veins
What are the 4 cranial dural septa?
Falx cerebri
Tentorium cerebelli
Falx cerebelli
Diaphragma selae
Where is the falx cerebri found and what does it separate?
In the longitudinal fissure; separates the R and L hemispheres
What 2 major veins are found within the falx cerebri?
Superior sagittal sinus
Inferior sagittal sinus
What shape does the tentorium cerebelli resemble and what structures does it separate?
Resembles a tent; separates the cerebrum from the cerebellum
What major blood vessels are found within the tentorium cerebelli?
Transverse sinuses
What does the diphragma selae separate?
Separates the pituitary and the hypothalamus
What is the purpose of the brain ventricles?
Buoyancy
Protection
Environmental stability
Where are the 2 lateral ventricles found?
One in each hemisphere
Where is the 3rd ventricle found?
In the diencephalon
Where is the 4th ventricle found?
Between the pons and the cerebellum
How does the 3rd ventricle communicate with the lateral ventricles and the 4th ventricle?
Lateral ventricles: interventricular foramen
4th ventricle: cerebral aqueduct
How much CSF is produced a day by the choroid plexuses?
500ml/day
What 2 structures allow CSF to flow into the subarachnoid space?
Lateral and median apertures
General function of the left and right hemispheres:
Left: speech, writing, language, math
Right: spatial visualization, touch analysis
What is the function of the precentral gyrus?
Voluntary movement via somatic motor neuron control in the brain stem and spinal cord; AKA primary motor cortex
What is the function of the postcentral gyrus?
Receive somatic sensory info for:
- touch
- pressure
- pain
- taste
- temp
All from the dorsal columns and spinothalamic tracts
What is another name for the precentral gyrus and postcentral gyrus?
Primary motor cortex; primary sensory cortex
Where is the insula found and what is its function?
Found folded within the lateral sulcus
Emotion, empathy, taste, self-awareness
What are the specific nuclei within the basal ganglia?
Caudate nucleus
Lentiform nucleus (putamen and globus pallidus)
Claustrum
Amygdaloid body
Function of caudate nucleus
Coordinate walking
Function of amygdaloid body
Emotional expression
Function of lentiform nucleus
Movement and muscle tone
Function of claustrum
Subconscious visual processing
What partially forms the roof of the diencephalon? What are its 2 components?
Epithalamus
- pineal gland
- habenular nuclei
What is the function of the habenular nuclei? 2
Relays info from limbic system to midbrain; visceral and emotional response to door
What is the only sense that the thalamus does not receive input from?
Olfaction
What functions does the hypothalamus control?
Autonomic functions, endocrine, temp, emotional behaviour, sleep-wake rhythms
What structure connects the hypothalamus to the pituitary gland?
Infundibulum
Where are the nuclei of many cranial nerves found?
Brainstem
What is the function of the midbrain?
Processes visual, auditory, and motor info - generates reflex response
What makes up the corpora quadrigemina?
2 pairs of sensory nuclei: superior and inferior colliculus x2
What does the superior colliculus process and what does the inferior colliculus process?
Superior colliculus: visual stimuli
Inferior colliculus: auditory stimuli
What are the cerebral peduncles?
Motor tracts
What other major structures are found in the brainstem?
Nuclei of the reticular formation
Red nucleus
Substantia nigra
What is the function of the reticular formation?
Maintaining alertness
What is the function of the red nucleus? 2
Involuntary motor commands
- muscle tone & limb position
What is the function of the substantia nigra?
DA production
- motor control
- emotion
- pleasure
- pain
What is the main function of the pons?
Contains autonomic nuclei that regulate breathing
What cranial nerve nuclei are found within the pons? 3
Trigeminal (V)
Abducens (VI)
Facial (VII)
What are the name of the tracts that are found in the medulla oblongata pyramids?
Corticospinal tracts
What cranial nerves are associated with the medulla oblongata?
VIII, IX, X, XI, XII
What is the purpose of the inferior olivary nucleus and where are they found?
Relays proprioceptive info to cerebellum; found in medulla oblongata
What major autonomic centres are found in the medulla oblongata?
Cardiovascular and respiratory
What is the function of the cerebellum? 4
Coordinates and fine-tunes skeletal movements
Stores movement patterns
Equilibrium and posture
Receives feedback
Where is arbor vitae found?
White matter in the cerebellum
What does the superior cerebellar peduncle connect? Middle? Inferior?
Superior: midbrain to cerebellum
Middle: pons to cerebellum
Inferior: medulla oblongata to cerebellum
What are the components of the limbic system? 7
Cingulate gyrus
Parahippocampal gyrus
Hippocampus
Amygdaloid body
Fornix
Mamillary body
Olfactory bulb
How does the limbic system affect memory formation?
Integration of past memories of physical sensation with emotional states
What does the fornix connect?
White matter connecting the hippocampus to the hypothalamus
List all 12 cranial nerves in order (anterior to posterior)
Olfactory (I)
Optic (II)
Oculomotor (III)
Trochlear (IV)
Trigeminal (V)
Abducens (VI)
Facial (VII)
Vestibulocochlear (VIII)
Glossopharyngeal (IX)
Vagus (X)
Hypoglossal (XII)
Accessory (XI)
What is the function and pathway of the olfactory (CN I) nerve?
Function: sensory (smell)
Pathway: cribriform plate of ethmoid
What is the function, pathway, and destination of the optic (CN II) nerve?
Function: sensory (vision)
Pathway: optical canal of sphenoid
Destination: occipital lobe, diencephalon
What is the function, origin, and pathway of the oculomotor (CN III) nerve?
Function: motor; extra-ocular and pupillae muscles
Origin: midbrain
Pathway: superior orbital fissure of sphenoid
What is the function and origin of the trigeminal (CN V) nerve?
Function: mixed function
- Sensory: touch, temp, pain
- Motor: muscles of mastication
Origin: pons
What is the function, origin, and pathway of the abducens (CN VI) nerve?
Function: motor, muscles of eye
Origin: pons
Pathway: superior orbital fissure
What is the function, pathway, and origin of the facial (CN VII) nerve?
Function: mixed
Pathway:
- sensory: taste (anterior 2/3)
- motor: muscles of facial expression, salivary glands
Origin: pons
What is the function and pathway of the vestibulocochlear (CN VIII) nerve?
Function: sensory - balance and hearing
Pathway: internal acoustic meatus
What is the function, pathway, and origin of the glossopharyngeal (CN IX) nerve?
Function: mixed
Pathway: jugular foramen
- sensory: taste (posterior 1/3)
- motor: muscles that assist swallowing; parotid salivary gland
Origin: medulla oblongata
What is the function, pathway, and origin of the vagus (CN X) nerve?
Function: mixed
Pathway: jugular foramen
- sensory: tongue, throat, heart, esophagus, abdominal viscera, and intestine
- motor: muscles of the throat, heart, lungs, larynx, trachea, and most abdominal organs
Origin: medulla oblongata
What is the function, origin, and pathway of the accessory (CN XI) nerve?
Function: motor, controls SCM, traps, some pharynx muscles
Origin: medulla oblongata
Pathway: jugular foramen
What is the function, pathway, and origin of the hypoglossal (CN XII) nerve?
Function: motor (controls tongue muscles)
Pathway: hypoglossal canal of occipital bone
Origin: medulla oblongata
What is the overall function of the somatic nervous system? 2
Sensory info of vision, hearing, touch, proprioception, etc
Motor info to control skeletal muscles
How are the parasympathetic and sympathetic preganglionic axons different?
Parasympathetic: long preganglionic axons
Sympathetic: short preganglionic axons
What is different between the parasympathetic and sympathetic branches of the autonomic nervous system in relation to the number of preganglionic branches?
Parasympathetic: preganglionic axons have few branches
Sympathetic: preganglionic axons have many branches
What branch of the ANS has ganglia very close, or on the effector?
Parasympathetic division
What is another term for the parasympathetic division and why is it named as such?
Craniosacral division; because preganglionic neurons are found within the brainstem and the sacral region of the spinal cord
What kind of activation is seen in the parasympathetic division of the ANS? Widespread, local, etc
Discreet and local activation for rest and digest
What are the 4 nerves that carry parasympathetic fibres?
CN III
CN VII
CN IX
CN X
At what level(s) do the 3 nerves from the sacrum exit in the parasympathetic system? What do they innervate?
S2, S3, S4
Innervate visceral organs of inferior abdominopelvic region
What is another term for the sympathetic division of the ANS and why is it named as such?
Thoracolumbar division; preganglionic cell bodies are found in T1-L2 segments of spinal cord
Where are the 2 locations of sympathetic ganglia found?
Paravertebral ganglia (sympathetic trunk): either side of vertebral column
Prevertebral column: anterior to the vertebral column
In the sympathetic trunk ganglia, which section of the ganglia exclusively have white rammus communicantes?
Ganglia of T1-L2
What are the 3 pathways to exit the sympathetic chain?
Spinal nerve
Sympathetic nerve
Splanchnic nerve
What fibres are carried in the thoracic and abdominopelvic cavities of the autonomic plexuses?
Mix fibres (SN & PN)
What are 4 exceptions to dual innervation of the ANS?
- blood vessels
- sweat glands
- arrector pili m
- adrenal medulla
All SNS only
What is the function of the pericardium?
Restricts movement, decreases friction
What are the names of the 2 walls of the pericardium?
Parietal pericardium (outer)
Visceral pericardium (inner)
What type of connective tissue is on the parietal layer and what is its name?
Dense irregular CT
Fibrous pericardium
How much fluid does the pericardial cavity contain?
10-20mL of fluid
What is the fibrous pericardium attached to?
Inferiorly to diaphragm
Superiorly to great vessels
What 2 areas is the pericardial fat found in?
Pericardial fat (visceral)
Paracardial fat (parietal)
What is the function of the pericardial fat?
- immune barrier
- mechanical protection
- source of energy
What are the external boundaries of the heart?
Atrioventricular groove
Interventricular groove (anterior & posterior)
What is another name for the auricles? What is their purpose?
Atrial appendage
Allows for slight atrial expansion