final exam terms Flashcards
an atom or group of atoms that has an unpaired (extra) electron and is therefore unstable and highly reactive
free radical
chemically relative molecules containing oxygen
reactive oxygen species (ROS)
an imbalance between the production of reactive oxygen species and the bodies ability to detoxify the free radicals or repair damage
oxidative stress
enzyme that is part of the detoxification of reactive oxygen species
Superoxide dismutase (SOD)
Alzheimer’s disease
Amyloid Beta 42 peptide in amyloid plaques
neurofibrillary tangles
hyperphosphorylated tau
Lewy bodies
Alpha-synuclein
Alzheimer’s disease affects which region of the brain?
hippocampus, cortical and limbic structures
Parkinson’s disease affects which region of the brain?
substantia nigra (and linked cortical regions)
ALS affects which region of the brain?
Spinal cord (and precentral gyrus- part of the primary motor cortex)
subcortical brain structures that are crucial in planning, organizing and executing movement, addiction
basal ganglia
a nucleus in the basal ganglia involved in initiating voluntary movement. Contain a lot of dopaminergic neurons
substantia nigra
one of the three major classes of glia in nervous system, controls the ionic environment of neurons and can be involved in neurotransmitter reuptake
astrocyte
a stimulus that produces a natural, automatic reaction
unconditioned stimulus
a previously neutral stimulus that, after repeated association with an unconditioned stimulus, elicits the response produced by the unconditioned stimulus itself.
conditioned stimulus