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Biochem I Study Questions > Final Exam > Flashcards

Final Exam Flashcards

1
Q

Von Gierke’s disease is synomymous with a glucose 6-phosphatase deficiency.
True or False.

A

True

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2
Q

Rate limiting enzyme in the pentose phosphate pathway ____.

A

G6P dehydrogenase

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3
Q

Insulin is secreted by alpha cells from the pancreas.

True or False

A

False

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4
Q

Insulin has the following effects:

A

Increase storage of high energy fuels

Increase glycogenesis

Decrease GNG

Decrease glycogenolysis

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5
Q

Cori disease is synonymous with glycogen debranching enzyme.

True or False

A

True

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6
Q

Most common cause of type-2 diabetes

A

Obesity

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7
Q

G6P is converted into G1P via

A

Phosphoglutomutase

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8
Q

Isomers denoted as alpha and beta forms are

A

Anomers and diastereomers

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9
Q

The final products of digestion are

A

Glucose, galactose, fructose

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10
Q

Provides electrons to antioxidant enzymes

A

NADPH

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11
Q

Functions of cytochrome P450 mono-oxygenase include

A

Biosynth steroid hormones, detox toxins inside smooth ER, and detox drugs inside the smooth ER

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12
Q

The unpaired electron in nitrogen monoxide is

A

A free radical

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13
Q

The primary product of the pentose shunt pathway is

A

Sugars

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14
Q

The pathway that is a primary source of ribose in the body is

A

Pentose shunt pathway

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15
Q

2 hormones released in concert with epinephrine and norepinephrine to regulate metabolism

A

Insulin and glucagon

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16
Q

The primary enzyme for glycogen synthesis is

A

Glycogen synthase

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17
Q

The following are products of the pentose phosphate pathway

A

NADPH, ribose 5-P, CO2

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18
Q

NADPH uses include

A

Phagocytosis by WBCs, cytochrome P40 mono-oxygenase system, and reductive biosynthesis

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19
Q

G-protein coupled receptor is associated with

A

Glucagon and epinephrine

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20
Q

Glycogen synthase is active when it is

A

Dephosphyrolyated by insulin

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21
Q

Glycogenolysis occurs in the

A

Cytosome

22
Q

Processing of preproinsulin to proinsulin occurs in the

A

Smooth ER

23
Q

Insulin resistance can cause the following effects

A

Increase adipose lipolysis, increase hepatic gluconeogenesis, increase blood glucose

24
Q

Transport protein associated with skeletal muscle and adipose tissue

A

Glut-4

25
Q

Catalyzes reaction for the conversion of citrate to isocitrate

A

Aconitase

26
Q

Nitric oxide is

A

A vasodilator of smooth muscle

27
Q

Km is unaffected, Vmax is lower with

A

Non-competitive inhibition

28
Q

If keq < 1 and delta G > 1

A

The reaction favors the reactants

29
Q

Product of pyruvate oxidation that enters the Krebs Cycle

A

Acetyl-CoA

30
Q

Monosaccharides can form cyclical structures.

True or False

A

True

31
Q

What class of enzymes forms C-S, C-O, and C-N bonds between subunits?

A

Ligase

32
Q

Unique to gluconeogenesis

A

Oxaloacetate to PEP

33
Q

Enzyme that uses water to remove the phosphoryl group

A

Phosphatase

34
Q

Pair of mobile electron carriers in the ETC

A

CoQ and cytochrome C

35
Q

A positive delta G is

A

A net gain of energy; products have more free energy than reactants

36
Q

The following are components of complex IV of the ETC

A

Water released, Cyt A3 component, and electrons transferred to molecular oxygen

37
Q

Glycogen synthase is

A

The enzyme responsible for linking glucose, makes alpha 1-4 linkages, and cannot link free glucose of G1P

38
Q

Amino acid containing a disulfide bond

A

Cysteine

39
Q

The final processing of proinsulin to insulin takes place in the

A

Golgi

40
Q

The Krebs cycle takes place in the

A

Mitochondria

41
Q

The Kreb’s Cycle produces how many ATP for 1 molecule of acetyle-CoA?

A

24

42
Q

2 vitamins associated with NADH and FADH2

A

Riboflavin and Niacin

43
Q

Functions as a cofactor that aids in the transfer of CO2 groups

A

Biotin

44
Q

Product of glycolysis under anaerobic conditions

A

Lactate

45
Q

Amount of ATP technically made from the TCA cycle

A

0

46
Q

If keq=1 and delta G=0

A

A system is in equilibrium

47
Q

Sucrose is a combination of

A

Fructose + Glucose

48
Q

Glycine is special because

A

It is achiral, it doesn’t have 4 different bonding sites

49
Q

Allosteric regulation changes

A

Activity of enzyme by binding an effector

50
Q

Max buffering capacity occurs when

A

pH=pKa

Biochem I Study Questions (3 decks)

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