Final exam Flashcards
Know topics 1-8
Parts of a Neuron
- Dendrites 2. Axon Hillock 3. Axon 4. Synapse
Function of Dendrite
Input
Function of Axon Hillcock
Integrative
Function of Axon
Conductive
Function of Synapse
Output
The type of neuron connection we focus on
Axodendritic Synapse (Synapses on dendrites)
What is the synaptic cleft
Gap between synapse between two neurons
What do cell membranes do?
Prevent flow of ions, proteins, and other water soluble molecules
What is a membranes resting potential
- 70 mV
Two main types of conduits across the membrane
Ion channels and Ion pumps
Ion channel characteristics
Passive transport, selective permeability, and can be gated. (It allows Na+, K+, Ca2+, Cl-)
Ion pump characteristics
Active transport, and requires energy (ATP) (it allows Na+, K+, Ca2+)
What forces push ions through channels
Electrical gradient (in) and Concentration gradient (out)
What happens when gradients are equally opposite
Electrochemical equilibrium
According to the Nernst Equation what does not help determine equilibrium
The Permeability of other ions
Why is there a diffusional force for potassium ions from inside to outside the cell membrane?
Due to greater concentration of potassium ions inside the membrane compared to the outside
What voltage dependent process initiates an action potential
Voltage-gated sodium channel open, letting more sodium ions into the neuron
Why do action potentials only go one way down an axon
Refractoriness: after a action potential that piece of membrane has a cooldown period before it can go again
What happens when Hyperpolarization occurs
An inhibitory Postsynaptic Potential (IPSPs)
What happens when Depolarization occurs
Excitatory Postsynaptic Potential (EPSPs)
What happens when a Action potential occurs (Spike)
Rapid depolarization and repolarization
What threshold does a Action potential occurs
-55 mV
What does All or non mean
an action either occurs to a full 100 mV or it does not occur, it lasts 1 ms, and has a refractory period of 5 ms
Characteristics of Electronic conduction
- Passive
- Relatively fast
- Exponentially attenuating
- Travels short distances
Characteristics of self-regenerating propagation
- Active
- Relatively slow
- Self-regenerating
- Travels long distances
What are two components of Saltatory conduction
Nodes of Ranvier and Myelinated sections
What are the 3 parts of neural coding
- Rate 2. Duration 3. Timing
What do Postsynaptic Potentials depend on
Neurotransmitters (from the presynaptic cell)
Receptors (on the postsynaptic cell)
What CNS neurotransmitter is the primary excitatory neurotransmitter
Glutamate
What Major CNS neurotransmitter is the primary inhibitory neurotransmitter
GABA
What are some other Major CNS neurotransmitters
Acetylcholine, Dopamine, Serotonin, Noradrenaline, Histamine
Neurotransmitter Biochemical classifications
- Amino acids (Glutamate, GABA)
- Monoamines (Dopamine, Norepinephrine, Histamine, Serotonin)
- Peptides (Oxytocin, Endorphin, Somatostatin)
- Gases (Nitric oxide, Carbon monoxide)
- other (Acetylcholine)
Topic 2 Part 1 Foundation: Brain
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What are Glia
Non-neuronal cells in the nervous system
What are Glia functions
- Support neurons physically
- Supply neurons with nutrients and oxygen
- Insulate neurons from eachother
- Protect neurons from pathogens and clean out dead neurons
- Modulate and regulate neural activity
How many Glia celss are there
100 BILLION (1/2 OF CNS volume)
Function of Astrocytes (CNS) and Satellite Cells (PNS)
- support neurons structure
- Help create blood brain barrier
- Provide nutrients
- Modulate neural activity through reuptake in neurotransmitters and regulates ion concertation
Function of Oligodendrocytes (CNS) and Schwann cells (PNS)
Provide the myeline for axons
Ependymal cells (CNS)
Help produce and circulate cerebrospinal fluid
Microglia (CNS)
Macrophages that devour and digest cellular debris
What are the body centric direction terminology
- Dorsal= back
- Ventral=belly
- Rostral= nose
- Caudal= tail
Space centric direction terminology
- Superior=above
- Inferior=below
- Anterior= before (in front)
- Inferior=after (behind)
Side to side direction terminology, same or different side terminology
1. Ipsilateral
2. Contralateral
- Same side
- Opposite side
One or both
1. Unilateral
2. Bilateral
- one side
- both sides
Left or right
left or right lateralized
near or far
Proximal= near
Distal= far
What are the 2 divisions of the PNS
Somatic ( Voluntary control)
Autonomic (regulation of involuntary functions eg organs)
Autonomous nervous system
Autonomic motor neuron steps
- Brain stem/ Spinal cord
- Sympathetic and parasympathetic ganglia cells
- Effector cells (Smooth muscle cells, gland cells, Cardiac muscle cells)
Why do sympathetic and parasympathetic functions work against each other
To achieve homeostasis
Sympathetic functions
- Fight or flight
- quick response
- increase blood flow to skeletal muscle
- increased heart rate
inhibits digestion - pupils dilate
Parasympathetic
- Rest and digest
- increase blood flow to gut
- Facilitates digestion
- Constricts pupils for near vision
CNS Protection
Meninges: covering
Cerebrospinal fluid (CFS): cushioning
Ventricles: fluid filled spaces
3 Layers of Meninges
- Dura Mater
- Arachnoid mater
- Pia Mater
Ventricles (4)
Left lateral
right lateral
third
fourth
Cerebrospinal Fluid functions
Buancy and protection
Chemical stability
clearing of waste
Types of matter in spinal cord and what they are (2)
White Matter: Myelinated axons
Grey Matter: Cell bodies of neurons
Afferents
Signals coming in from the peripheral come in through the dorsal side (Senses)
Efferent
Signals coming out of the Ventral side are sent to the peripherals (muscles)
Major Development Divisions of Brain
Telencephalon, Diencephalon (Forebrain)
Mesencephalon (Mid Brain)
Metencephalon, Myelencephalon ( hind brain )
What are the parts of the Mid brain (mesencephalon)
- Superior colliculus
- Inferior colliculus
- Motor Nuclei
what are the parts of the Hind brain
Pons (Metencephalon)
Medulla (Myelencephalon)
Medulla Functions
Breathing, heart rate, blood pressure
Pons
Balance, taste, Swallowing
Subcortical Structures
Hippocampus
Basal Ganglia
Hypothalamus
Thalamus
Cerebellum
Basal Ganglia Components
Caudate
Putamen
Globus pallidus
Nucleus acumbens
What is an important function of the Amygdala and Hippocampus
Episodic long term memory
Lobes of the Cerebral cortex
Frontal
Parietal
Occipital
Temporal
What are sulci and fissures
Folds/clefts in the cortex
Important sulci and fissures for class
Sylvian Fissure (separates temporal lobe from frontal lobe)
Central sulcus (separates Frontal lobe from Parietal lobe)
Longitudinal fissure (Separates left and right hemisphere)
Sulci hidden inside the midbrain
Cingulate sulcus (
Calcarine sulcus (primary visual cortex sits on top of it)