final exam Flashcards
what are carbohydrates made of?
carbon and water
are carbohydrates soluble in water?
yes, since they are polar (they have oxygen)
which macromolecules are polymers?
carbohydrates, proteins, nucleic acids
are lipids soluble in water?
no, since they are nonpolar. Nonpolar molecules don’t mix with polar (water).
what are lipids made up of?
C and H
are proteins soluble in water?
some are, some are not. It depends on the type of amino acids and R-groups that make the amino acid.
which types of amino acids add reactivity to the protein?
charged ones
are nucleic acids soluble in water?
yes, they are polar molecules
what are nucleic acids made of?
- a nitrogenous base
- a five carbon ring shaped sugar
- one to three phosphate groups
what are the 4 polysaccharides?
- chitin and cellulose
- glycogen and starch
what is the function of chitin?
support and rigidity
what is the function of cellulose?
support and rigidity
what is the function of glycogen?
energy storage (in animals)
what is the function of starch?
energy storage
what are the 4 groups of amino acids?
- nonpolar
- uncharged polar
- negatively charged polar
- positively charged polar
what are uncharged amino acids?
uncharged but have oxygen so polar
which types of amino acids are polar?
uncharged, negative, positive
how do amino acids affect the function of the protein?
- the type of R-group (soluble or not, polar or not)
- the type of amino acid (soluble or not, polar or not)
- the way they are folded
- different combinations of amino acids
what are some similarities between archea and bacteria?
- no nucleus
- single chromosome
- no organelles
- ribosomes
what are some differences between archea and bacteria?
- archea have histones, not bacteria
- bacteria have peptidoglycan, not archea
- archea has multiple RNA polymerase
what are some similarities between bacteria and eukarya?
ribosomes
what are some similarities between archea and eukaryotes?
- histones
- multiple RNA polymerase
- ribosomes
what are some differences between prokaryotes and eukaryotes?
- eukarya has a nucleus
- eukarya has more than 1 chromosome
- eukarya have organelles
what are the unique characteristics of eukaryotes?
- seperation of DNA and cytoplasm by a nuclear envelope (nucleus)
- presence of organelles (membrane bound compartments with specialized function) in the cytoplasm
what are the characteristics of protists?
- mostly unicellular
- nucleus and multiple linear chromosomes
- organelles (mitochondria, chloroplast, microtubules; motility and cytoskeletal support)
what are the characteristics of fungi?
- they have a cell wall made of chitin
- they can release enzymes and produce antibacterial compounds
what are the characteristics of animals?
- muticellular
- no cell wall
- heterotrophs
- use O to metabolize food
- store excess energy as glycogen
- motile at some point in their lives
- reproduce asexually or sexually
what are the characteristics of plants?
- have a cell wall made of cellulose
- produce chlorophyll as a photosynthesic pigment
- store excess sugar as starch
- have 2 multicellular phases
- multicellular
how are chromosomes during G1?
unreplicated, 2 pairs of each chromosomes (2n)
how are chromosomes during G2?
each chromosome is doubled (2 sister chromatids) (2N)
how are the chromosomes during prophase?
they condense into threads that become visible under the microscope. They are still double (2N)
how are the chromosomes during prometaphase?
the microtubules attach to kinetichores of each chromosome. (2N)
how are the chromosomes during metaphase?
they align at the spindle midpoint (metaphase plate) (2N)
how are the chromosomes during anaphase?
- now 92 chromosomes
- now 4n : 4 unreplicated chromosomes
- spindle separate the 2 sister chromatids and move them to opposite spindle poles creating daughter chromosomes
how are chromosomes during telophase?
they unfold and return to interphase state (4n)
how many chromatids are there per chromosome?
2
what does diploid mean?
there are 2 copies of each chromosome (2n)
what does haploid mean?
there is one copy of each chromosome (1n)
what is mitosis?
a process in which a cell replicates its chromosomes, segregate them, producing 2 identical nuclei in peparation for cell division. It creates another identical cell.
what is meiosis?
a process to create gametes (sex cells) - 1n
what phases are in interphase?
G1, G2, S phase
what is G1 in mitosis?
- unreplicated chromosomes
- organelles grow
- RNA and proteins are synthesized
what is S-phase in mitosis?
DNA is replicated
what is G2 in mitosis?
-chromosomes are now 2 sister chromatids held together by a centromere
- DNA is checked for mistakes
- centrioles (in centrosome) have doubled in pairs
what is prometaphase in mitosis?
-microtubules generated by spindles attach to kinetochores of each chromosome
what is metaphase in mitosis?
- chromosomes align on metaphase plate
what is anaphase in mitosis?
- spindle seperates the 2 sister chromatids of each chromosome and move them to opposite spindle poles
- centromeres break
- 4 unreplicated chromosomes
what is telophase in mitosis?
- chromosomes decondense, unfold, and return to interphase state
- nucleus reforms (2)
- cytoplasm begins to divide
what is cytokinesis in mitosis?
cytoplasm cleaves and divides into 2 daughter cells
what is the interphase of meiosis?
same as mitosis (2n - 2N)
what happens during prophase I in meiosis?
- chromosomes begin to condense (2 sister chromatids per chromosome)
- synapsis: homologous chromosomes come together and pair (4 chromatids within 2 homologous chromosomes - tetrad)
- recombination: chromatids of homologous chromosomes undergo recombination and exchange segments
what ensures genetic diversity?
- recombination
- independant assortment of chromosomes in meiosis
ploidy prophase 1 meiosis
2N
what happens in prometaphase I of meiosis?
same as mitosis (2N)
what happens in metaphase I?
- homologous pairs of chromosomes align randomly on metaphase plate = independant assortment
ploidy metaphase I
2N
what happens in anaphase I?
- seperation of 2 chromosomes of each homologous pair and move to opposite spindle
- no break in centromeres
- poles now contain the haplooid number of chromosomes
Ploidy anaphase I
2N
what happens in telophase I?
- chromosomes undergo little to no change (don’t decondense)
- first spindle disassembles and 2 new ones are created
ploidy telophase I
1N (division of cell)
what happens after telophase I?
Prophase II
what happens in prophase II?
- chromosomes condense and a spindle forms
- no prometaphase since there is no nuclear membrane
ploidy prophase II
1N
what happens in metaphase II?
chromosomes align on metaphase plate
ploidy metaphase II
1N
what happens during anaphase II?
- microtubules seperate chromatids of each chromosome and go to opposite poles (2n)
ploidy anaphase II
2n
what happens in telophase II?
- chromosomes decondense
- new nuclear envelope
ploidy telophase II
4 times 1n cells
what is the effect of genetic recombination on chromosomes?
genetic recombination causes bits of genetic info to be exchanged to create new combinations of DNA in each chromosome
Explain the relationship between meiosis, the segregation of chromosomes, and the transmission of alleles from parent to offspring.
During prophase 1: recombination and exchange in segments between homologous chromosomes
During metaphase 1: homologous chromosomes align randomly on metaphase plate (maternal and paternal are randomly placed on a side of the metaphase plate (pole))
The way they line up determines how they segregate in the cell and how end up in daughter cells (some have more maternal, or more paternal, etc)
Since there are infinite possibilities of assortments, there are infinite possibilities of gametes
what is complete dominance?
the dominant allele completely masks the effect of the recessive
what is incomplete dominance?
a new phenotype that is the blend of the two
what is codominance?
- both phenotypes are expressed (not mixed)
- no new phenotype
what is a centromere?
holds sister chromatids together
lethal alleles
dont evolve, no phenotype
lethal recessive alleles
no phenotype for the recessive (3:0)
lethal dominant alleles
Rare, since it usually results in death before reproduction (0:1)