Final Exam Flashcards
What is sperm capacitation?
When a sperm undergoes changes in the female reproductive tract to become able to fertilize egg
What occurs during capacitation?
Sperm head made more fragile and Ca2+ enters it, activation of acrosomal enzymes
B protein used to attach sperm to ovum
Attach to membrane
Alpha proteins used to attach sperm to ovum
Insert through membrane
What happens when the sperm enters the ovum?
Digests hole through zona pellucida, detaches tail, disrupts cortical granules
Fast block to polyspermy
Influx of Na+ and release of Ca2+ from cortical granules to depolarize membrane
Slow block to polyspermy
Release of sperm from protein B, downregulate protein B, cleave protein A using zonal inhibiting proteins
Normal pH
7.35 - 7.45
What do syncytiotrophoblasts do?
Active invasion of the endometrium, release of digestive enzymes to break down uterine vessels and endometrial glands
How does blastocyst differentiate?
Cytotrophoblast and syncytiotrophoblast
Umbilical arteries = ________
Deoxygenated fetal blood
Umbilical veins = ________
Oxygenated fetal blood
What does HCG (human chorionic gonadotropin) do?
Maintain corpus luteum hormone production until placenta fully formed
hPL
Human placental lactogen
Stages of childbirth
Early dilation, rupture of amniotic sac, late dilation, expulsion, afterbirth