Final Complete Revision Flashcards
What is bedrest an accelerated model of
Aging
What is bedrest most commonly used for
Injury and recovery
What does bedrest decrease
1) Blood flow to the brain
2) Brain glucose
What do bedrest studies help us understand
What happens in the body as we age
After 5-10 days how much muscle strength is loss
10%
How long does it take to regain the muscle mass loss after 14 days of bedrest
One year
After how many days of bedrest does your body adapt
40 days
How many year’s of cardiovascular changes happen in astronauts after 6 months in space
20 years
What blood volume is loss by astronauts in the first 24-48H
20%
What are astronauts at a higher risk of getting
Diabetes because they don’t need to contract muscles as they don’t have gravity which increase the sugar in the blood.
What new tool has been innovated to help astronauts contract their muscles
ARED
What situation is a simulation of space
6 degree head tilt bedrest
Name all the negative aspects of astronauts
1) Increase Aging
2) Decrease Blood volume
3) Loose lean mass
4) Fat mass gain
How long was the 6 degree headown tilt study overall
26 days
How long was the test actually performed and after how many days of adaptation did it start
The test began for a 14 days duration after a 5 days adaptation period.
In the 6 degree study, both groups (exercise and control) equally lost what
Muscle strength
VO2max was enhanced in what group in comparison to the other group whom significantly decreased
Exercise
The number of mitochondrias was loss in what group
Control
The 6 degree headown tilt is a reproduction of what
Weightlessness on earth
What is glycogen
Stored glucose
Where is glycogen found in
Liver and Muscle
What is the primary energy source
Muscle glucose
What is needed to allow glucose to enter or exit the cells of the liver and muscle?
Glut2 and Glut-4
What are the ONLY two ways to activate Glut2 and 4
1) Insulin
2) Muscle Contraction
What is glucose utilization
Process of how we use glucose as energy
What two enzymes are needed to complete the reaction related to glucose utilization
1) Glucose 6-phosphate
2) Hexokinase
Which of the two enzymes involved in glucose utilisation is the only one needed if glucose is already in the cell
Glucose -phosphate