Final: Cellular Respiration Flashcards
What are the four stages of CR?
- Glycolysis
- Pyruvate Oxidation
- Kreb Cycle
- Oxidative Phosphorylation
What is the goal of CR?
To make ATP
Locations of the steps of CR?
- Cytoplasm
- Translocation from cytoplasm to mito matrix
- Mito Matrix
- Across inner membrane
What is a negative feedback loop? example?
loop where the end product is able to influence the activity
principle of homeostatic regulation
example- PFK and ATP
What are energy carrier molecules in CR?
NADH
ATP
Which molecules are low/high energy?
Low:
NAD+
FAD
GAP
High:
NADH
FADH
GTP/ATP
What are thermodynamically linked chemical reactions?
The product og one reaction become the reactants of the next reaction
What is the structure of mitochondria and how does it enable cellular respiration?
mito has double membrane
allows for compartmentalization. aerobic respiration
What evidence do we have that the Kreb Cycle is a cycle?
measured amounts of acids after manipulating specific parts of the pathway
measuring outputs
How do electron carrier feed into oxidative phosphorylation?
NADH binds to PC1 and makes 3 H+
FADH binds to PC 2 and pumps 2 H+
How does ATP synthase work
Powered by H+ ion gradient
When H+ ions move through ATP synthase down the concentration gradient they power a turning of a wheel at the bottom of ATP synthase that sticks ADP and Pi together (Which makes ATP)
How does the pH of the matrix compare to the pH of intermembrane space?
the pH of the matric is high then the intermem space
matric has lower H+ concentration
pH of intermem space is lower
intermem space has higher H+ concentration
What does the H+ gradient contribute to ATP synthsis
H+ gives it the energy and power that it needs to run
Inputs and outputs of Glycolysis
ins: 2 ATPs, Glucose
outs: 2 ATPs, 2 NADH, 2 3-C Pyruvates
Inputs and outputs of pyruvate oxidation
ins: Pyruvate
outs: Acetyl Co-A, Carbon Dioxide
