Final: Cellular Respiration Flashcards

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1
Q

What are the four stages of CR?

A
  1. Glycolysis
  2. Pyruvate Oxidation
  3. Kreb Cycle
  4. Oxidative Phosphorylation
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1
Q

What is the goal of CR?

A

To make ATP

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2
Q

Locations of the steps of CR?

A
  1. Cytoplasm
  2. Translocation from cytoplasm to mito matrix
  3. Mito Matrix
  4. Across inner membrane
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3
Q

What is a negative feedback loop? example?

A

loop where the end product is able to influence the activity
principle of homeostatic regulation
example- PFK and ATP

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4
Q

What are energy carrier molecules in CR?

A

NADH
ATP

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5
Q

Which molecules are low/high energy?

A

Low:
NAD+
FAD
GAP
High:
NADH
FADH
GTP/ATP

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6
Q

What are thermodynamically linked chemical reactions?

A

The product og one reaction become the reactants of the next reaction

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7
Q

What is the structure of mitochondria and how does it enable cellular respiration?

A

mito has double membrane
allows for compartmentalization. aerobic respiration

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8
Q

What evidence do we have that the Kreb Cycle is a cycle?

A

measured amounts of acids after manipulating specific parts of the pathway
measuring outputs

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9
Q

How do electron carrier feed into oxidative phosphorylation?

A

NADH binds to PC1 and makes 3 H+
FADH binds to PC 2 and pumps 2 H+

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10
Q

How does ATP synthase work

A

Powered by H+ ion gradient
When H+ ions move through ATP synthase down the concentration gradient they power a turning of a wheel at the bottom of ATP synthase that sticks ADP and Pi together (Which makes ATP)

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11
Q

How does the pH of the matrix compare to the pH of intermembrane space?

A

the pH of the matric is high then the intermem space
matric has lower H+ concentration
pH of intermem space is lower
intermem space has higher H+ concentration

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12
Q

What does the H+ gradient contribute to ATP synthsis

A

H+ gives it the energy and power that it needs to run

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13
Q

Inputs and outputs of Glycolysis

A

ins: 2 ATPs, Glucose
outs: 2 ATPs, 2 NADH, 2 3-C Pyruvates

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14
Q

Inputs and outputs of pyruvate oxidation

A

ins: Pyruvate
outs: Acetyl Co-A, Carbon Dioxide

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15
Q

Inouts and outputs of Kreb Cycle

A

ins: Acetyl Co-A
outs: 2 Co2, 1 FADH2, 1 GTP

16
Q

inputs and outputs of Oxidative Phosphorylation

A

ins: NADH, FADH2
outs: ATP

17
Q

Location of glycolysis?

A

Cytoplasm

18
Q

Location of Pyruvate Oxidation?

A

Translocates across the cytoplasm into the mito membrane

19
Q

Location of Kreb Cycle

A

Mito Membrane

20
Q

Location of Oxidative phosphorylation?

A

Across the inner membrane

21
Q

Purpose of glycolysis

A

To break down 6-carbon sugars into 3-c pyruvates

22
Q

Purpose of Pyruvate oxidation

A

1 chemical reaction
3-c pyruvate turn to 2-c Acetyl Co-A

23
Q

Purpose of Kreb Cycle

A

Acetyle Co- A

24
Q

Purpose of Oxidative phosphorylation

A

harvest energy from energy carrier molecules