Final Flashcards
what are adrenal glands?
cresent shaped hypoechoic structures surrounded by echogenic fat
what are the regions of adrenal glands?
- medulla=inner portion
- cortex=outer portion
what percent of the medulla comprises the gland?
10%
what percent of the cortex comprises the gland?
90%
where is the adrenal gland located in the body?
gerota’s fascia within the perinephric space
where is the adrenal gland located to the kidney?
- anterior
- medial
- superior
where is the right adrenal located?
posterolateral to the IVC
where is the left adrenal located?
- lateral to aorta
- posteromedial to splenic artery and tail of the pancreas
what is the vascular supply of the adrenal glands?
- superior suprarenal artery
- middle suprarenal artery
- inferior suprarenal artery
- Rt suprarenal vein
- left suprarenal vein
where does the superior suprarenal artery arise from?
inferior phrenic artery
where does the middle suprarenal artery arise from?
lateraal aspect of the aorta
where does the inferior suprarenal artery arise from?
renal artery
where does the right suprarenal vein drain?
IVC
where does the left suprarenal vein drain?
left renal vein
what are the adrenal functions?
- endocrine glands
- produce hormones
- medulla secretes epinephrine and norepinephrine
- corte secretes glutocorticoids, gonadal hormones, and mineral corticoids
what are some indications for scanning the adrenal glands?
- abnormal lab values
- increase in abdoinal girth
- chronic liver disease
- congestive heart failure
- etc
what are adrenal lab values?
- decreased hematocrit is suspicious for internal bleeding
- leukocytosis is suspicious for infection
- ACTH
- aldosterone
- potassium
- sodium
- glucocorticoids
where is adrenocorticotrophic (ACTH) produced?
pituitary gland
what is elevation of ACTH associated with?
- adrenal tumor
- cushing disease
- lung tumor
where is aldosterone secreted?
cortex
what is the funtion of aldosterone?
regulates sodium and water levels which affects blood volume and pressure
what is elevation of aldosterone associated with?
hyperaldosteronism
what is decrease in aldosterone associated with?
hypoaldosteronism
addison disease
what is essential to normal function of every organ system?
potassium
what is the elevation of potassium associated with?
addison disease
what is the decrease of potassium associated with?
cushing disease
hyperaldosteronism
what is the major component in determining blood volume?
sodium
what is the decrease in sodium associated with?
addison disease
Glutocorticoids
Regulation of the metabolism of glucose
Cortisol
It is released in response to stress and a low level of blood glucose
how is the left adrenal best visualized?
right lateral decubitus
how ia the right adrenal best visualized?
left lateral decubitus
what is the most commone adrenal tumor?
incidentalomas
-adenomas
where may benign adrenal neoplasms be in?
- increases with age
- hypertensive people
- diabetics
- hyperthyroidism
- RCC
- hereditary colorectal adenomatosis
Adrenal myelipoma
A rare benign neoplasm composed of mature adipose tissue and a variable amount of hematopoietic elements
Nonhyperfunctioning adenomas
more common
asymtomatic
Hyperfunctioning adenomas
Present clinically with symptoms related to excess hormone production
- cushing’s syndrome
- conn’s disease
Cushing’s syndrome
Excessive cortisol excretion
Hyperplastic glands
Cushing’s syndrome characterized by?
Truncal obesity Hirsutism Amenorrhea Hypertension Weakness
Conn’s disease
excessive aldosterone excretion
Conn’s disease characterized by
Hypertension
Muscular weakness
Tetany(muscle spasms)
ECG abnormalities
Pheochromocytoma
Neuroendocrine tumor of the medulla
hyperfunctioning Pheochromocytoma
Secrete norepinephrine and epinephrine into blood
clinical manifestations hyperfunctioning Pheochromocytoma?
Hypertension Severe headache Palpitations Tachycardia Excessive perspiration
who is Pheochromocytoma most frequently seen in?
40-60 years
is Pheochromocytoma curable?
rare but curable cause of hypertension
Pheochromocytoma sonographically
- 5-6cm in diameter-easily seen
- More often in right gland
- Well marginated
- May be calcified
- Heterogenous or homogenously solid
- May have areas of necrosis or hemorrhage
how do you diagnose rare benign adrenal tumors?
diagnosis must be made histologically
is Primary Adrenocortical cancer benign or malignant?
highly malignant
what does Primary Adrenocortical cancer show in hyperfunctioning?
Clinical manifestations of excess hormone production in hyperfunctioning tumors are apparent
what does Primary Adrenocortical cancer invade?
adrenal vein
IVC
lymphatics
when does Primary Adrenocortical cancer recur?
after surgical excision