Final Flashcards
1
Q
Anaphylaxis- intraop
A
- SS: HoTN, tachycardia, bronchospasm, pulmonary edema
- Tx= recognize SS, maintain airway, 100% O2, epinephrine IV, maintain BP with fluids or meds, Benadryl IV
2
Q
malignant hyperthermia - intraop
A
-SS early: tachycardia, rising BP, tachypnea, muscle rigidity
-SS late- increased temp, increased metabolic rate, HoTN, muscle rigidity, cyanosis
Tx- stop procedure, 100% O2, cool PT
Med- dantrolene sodium, diuretics, bicarb
3
Q
metabolic syndrome
A
- cluster of 5 components:
1. elevated glucose levels
2. abdominal obesity
3. increased triglycerides
4. Decreased HDLs
5. HTN
4
Q
T1DM 3 Ps
A
- polydipsia, polyuria, polyphagia (hungry)
5
Q
3 methods of diagnosis for DM
A
- fasting plasma glucose level > 126 mg/dl
- random or casual plasma glucose measurement ≥ 200 mg/dl + SS ( 3 Ps or others)
- Two-hour OGTT level≥ 200 mg/dl using glucose load of 75 g
6
Q
rapid acting insulin
A
- basal, bolus-
- Lispro , aspart, glulisine
- injected 0 -15 minutes before meal
- onset : 15 min
- Peak: 60-90 min
- Duration- 3-4 hrs
7
Q
Short-acting bolus insulin
A
- reg
- injected 30-45 min before meal
- Action: 30-60 min
- 2-3 hrs
- duration: 3-6 hrs
8
Q
intermediate acting insulin
A
- NPH or Lente
- injected 1 or 2 X a day
- onset : 2-4 hrs
- peak: 4-10
- duration: 10-16
9
Q
long-acting basal
A
- Lantus or Levimir
- injected once a day at bedtime or in morning
- released steadily and continuously
- onset: 1-2 hrs
- no peak action
- duration: 24 + hrs
- cannot be mixes with any other insulin
10
Q
Storage of insulin
A
- do not heat/freeze
- in-use vial may be left at room temp up to 4 weeks
- extra insulin should be refridgerated
- avoid exposure to direct sunlight
- prefilled syringes stable for 30 days when refridgerated
11
Q
sulfonylureas
A
- T2DM
- increase insulin production in the pancreas
- 10% experience decreased effectiveness after prolonged use
- ex. Glipizide, Glimepiride
12
Q
Meglitinides
A
- increase insulin production from pancreas
- taken 30 min before meal , don’t take if meal skipped
- ex. Repaglinide, Nateglinide
13
Q
Biguanides
A
- reduce glucose production by liver
- enhance insulin sensitivity at tissues
- improve glucose transport into cells
- do not promote weight gain
- Metformin: hold 24 hrs before/after use of IV contrast
14
Q
a-glucosidase inhibitors
A
- starch blockers
- slow down absorption of carbs in sm intestine
- Acarbose, Miglitol
15
Q
Meds that impact BGM
A
- B-adrenergic blockers- mask SS of hypoglycemia or prolong effects
- thiazide/loop diuretics- potentiate hyperglycemia by inducing K+
- corticosteroids- can potentiate hyperglycemia
16
Q
Hypoglycemia
A
-BGM < 70 CMs: -confusion, irritability, pale and diaphoretic -weakness -tremors -hunger -visual disturbances -unTreated: Loss of C. seizures, coma, death