Final Flashcards
Drugs that decrease lithium levels
Caffeine
Drugs that keep lithium levels u changed
Aspirin, acetaminophen
Drugs that increase lithium levels
Thiazides, NSAIDs, ACE-I, loop diuretics, salt restriction, dehydration
MAOI drug interactions
Other antidepressants, buspirone, dextromethorphan, Sympathomimetics
Phenytoin metabolism
CYP 2C9 and 2C19
VPA metabolism
Glucuronidation, beta-oxidation
Lamotrigine metabolism
Glucuronidation
AEDs that decrease lamotrigine levels
Carbamazepine, phenytoin, phenobarbital
What AED drug increases the Lamotrigine levels?
VPA
Lacosamide metabolism
CYP 2C19
Drugs that increases levels of Lacosamide
VPA
Which CYP does Oxcarbazepine inhibit?
CYP 2C19
Which enzymes do Oxcarbazepine stimulate?
CYP3A4 l, UGT
Topiramate drug interactions
Inhibits CYP 2C19
Induces CYP 3A4
Zonisamide metabolism
CYP 3A4
What drugs increase hormonal contraceptive levels?
Enzyme-inducing AEDs
Fomepizole
Antizol
Deferoxamine
Desferal
Naloxone
Narcan, Evzio
Assessing pain
P: provocative/palliate Q: quality R: region S: severity/scale T: time/triggers U: how does it affect u?
Hydrocodone products
Vicodin, Norcor, Lortab
Hydromorphone
Dilaudid