Enzyme Inducers/inhibitors Flashcards

1
Q

Carbamazepine

A

Induces Pgp, CYP 1A2/2C/3A, UGTs

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2
Q

Phenytoin

A

Induces Pgp, CYP 1A2/2C/3A, UGTs

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3
Q

Rifampin

A

Induces Pgp, CYP 1A2/2C/3A, UGTs

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4
Q

St. John’s Wort

A

Induces Pgp, CYP 3A

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5
Q

Ritonavir

A

Induces Pgp

Inhibits CYP 2D6/3A4

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6
Q

Tipanavir

A

Induces Pgp

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7
Q

Avasimbe

A

Induces Pgp

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8
Q

Phenobarbital

A

Induces CYP 1A2/2C/3A, UGTs

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9
Q

Felbamate

A

Induces CYP3A

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10
Q

Topiramate

A

Induces CYP3A

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11
Q

Oxcarbazepine

A

Induces CYP3A, UGTs

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12
Q

Griseofulvin

A

Induces CYP3A

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13
Q

Nevirapine

A

Induces CYP3A

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14
Q

Smoking

A

Induces CYP1A2

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15
Q

Alcohol

A

Induces CYP2E1

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16
Q

Lamotrigine

A

Induces UGTs

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17
Q

Oral contraceptives

A

Induces UGTs

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18
Q

Cyclosporin

A

Inhibits Pgp

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19
Q

Quinidine

A

Inhibits Pgp, CYP2D6

20
Q

Verapamil

A

Inhibits Pgp

21
Q

Amiodarone

A

Inhibits Pgp, CYP 1A2/2C9/2D6/3A4

22
Q

Erythromycin

A

Inhibits Pgp, CYP3A4

23
Q

Clarithromycin

A

Inhibits Pgp, CYP3A4

24
Q

Azithromycin

A

Inhibits Pgp

25
Q

Diltiazem

A

Inhibits Pgp, CYP3A4

26
Q

Ciproflaxacin

A

Inhibits CYP1A2

27
Q

Cimetidine

A

Inhibits CYP 1A2/2D6

28
Q

Ticlopidine

A

Inhibits CYP1A2

29
Q

Fluvoxamine

A

Inhibits CYP 1A2/3A4

30
Q

Fluconazole

A

Inhibits CYP 2C9/3A4

31
Q

Ketoconazole

A

Inhibits CYP 2C9/3A4

32
Q

Sulfamethoxazol

A

Inhibits CYP2C9

33
Q

Isoniazid

A

Inhibits CYP2C9

34
Q

Paroxetine

A

Inhibits CYP2D6

35
Q

Sertraline

A

Inhibits CYP2D6

36
Q

Fluoxetine

A

Inhibits CYP 2D6/3A4

37
Q

Methadone

A

Inhibits CYP2D6

38
Q

Indinavir nelfinavir

A

Inhibits CYP3A4

39
Q

Amprenavir

A

Inhibits CYP3A4

40
Q

Atazanavir

A

Inhibits CYP3A4

41
Q

Saquinavir

A

Inhibits CYP3A4

42
Q

Delavirdine

A

Inhibits CYP3A4

43
Q

Nefazodone

A

Inhibits CYP3A4

44
Q

Grapefruit juice

A

Inhibits CYP3A4

45
Q

Seville orange juice

A

Inhibits CYP3A4