Exam 4: Cytokines Flashcards

1
Q

Interleukin-2

A
Activates lymphocytes
Autocrine activity (activates T-cells to activate other T-cells)
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2
Q

Interleukin-4

A

Antibody production

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3
Q

Interleukin-17

A

Amplifies inflammation

Autoimmunity

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4
Q

Interferon y

A

Activation of macrophages

Up regulation of HLA I and II expression

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5
Q

Tumor necrosis factor a

A

Mediates inflammation

Prothrombic activity

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6
Q

Interferon b

A

Immunomodulation (decrease IFNy production/T-cell proliferation/BBB permeability)

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7
Q

Interleukin-1

A

Fever

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