FINAL Flashcards

1
Q

What is nociceptive pain?

A

Pain resulting from nociceptor activation due to tissue injury and resultant inflammation

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2
Q

What is neuropathic pain?

A

Pain resulting from direct insult to the nerve

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3
Q

How is fast sharp pricking pain transmitted to the spinal cord?

A

Fast sharp pricking pain is transmitted to the spinal cord via myelinated A-delta fibers

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4
Q

How is slow dull pain transmitted to the spinal cord?

A

Slow dull pain is transmitted to the spinal cord via unmyelinated C fibers

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5
Q

Primary Hyperalgesia

A

Sensitization of primary nociceptors after injury/inflammation

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6
Q

Central Hyperalgesia

A

Sensitization of Dorsal Horn Cells after injury

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7
Q

A-delta and C primary afferents synapse with these 3 things:

A
  1. Nucleus Proprius
  2. Pericornual Cells
  3. Substantia Gelitanosa
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8
Q

What are nociceptors?

A

Receptors that respond to noxious stimuli from skin/soft tissue injury

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9
Q

Preganglionic Sympathetics release __________, mediated by

___________ ?

A

Preganglionic Sympathetics release ACETYLCHOLINE, mediated by ACH NICOTONIC RECEPTORS

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10
Q

Preganglionic Parasympathetics release __________, mediated by
___________ ?

A

Preganglionic Parasympathetics release ACH mediated by NICOTONIC ACH RECEPTORS

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11
Q

Postganglionic Sympathetics release ______________, mediated by ____________ ?

A

Postganglionic Sympathetics release NOREPINEPHRINE , mediated by NORADRENERGIC RECEPTORS (alpha 1,2 ; beta 1,2,3)

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12
Q

Postganglionic Parasympathetics release ____________ , mediated by _____________ ?

A
Postganglionic Parasympathetics release ACH, mediated by
MUSCARINIC RECEPTORS (m1, m2, m3)
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13
Q

The Sympathetic and Parasympathetic systems innervate:

A
  1. Cardiac Muscle
  2. Smooth Muscle
  3. Glandular Tissue
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14
Q

Enteric division has greater _________ , mediates ____________ ?

A

Enteric division has greater AUTONOMY , mediates DIGESTIVE REFLEXES

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15
Q

Preganglionic Sympathetics are in the __________ of __________ ?

A

Preganglionic Sympathetics are in the INTERMEDIOLATERAL GRAY of T1-L2

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16
Q

Preganglionic Fibers exit through the __________ ?

A

Ventral Root

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17
Q

Preganglionic Fibers form the ____________ and enter the

____________ ?

A

Preganglionic Fibers form the WHITE RAMI COMMUNICANTES and enter the PARAVERTEBRAL SYMPATHETIC GANGLIA

18
Q

Preganglionic Sympathetic Fibers synapse with the sympathetic chain ganglia at what levels?

A

Same, Lower, and Higher

19
Q

Postganglionic Fibers form the ____________, and enter ______ ?

A

Postganglionic Fibers form the GRAY RAMI COMMUNICANTES and enter SPINAL NERVES

20
Q

How do Postganglionic Sympathetic Fibers from the Cervical, Thoracic, and Lumbar ganglia reach their target?

A

Via Spinal Nerves

21
Q

_____________ Sympathetic Fibers innervate peripheral blood vessels, sweat glands, and arrectores pilorum muscles.

A

Postganglionic Sympathetic Fibers

22
Q

Preganglionic Parasympathetic Cells are found in the __________ , and these Cranial Nerves __________ ?

A

Preganglionic Parasympathetic Cells are found in the INTERMEDIOLATERAL GRAY OF S2-4 and in CN III, VII, IX, X

23
Q

Preganglionic Cells in the brainstem are:

A
  1. Edinger-Westphal Nucleus (III)
  2. Superior Salivatory Nucleus (VII)
  3. Inferior Salivatory Nucleus (IX)
  4. Dorsal Motor Nucleus (X)
24
Q
  • Edinger-Westphal Nucleus will synapse with _____________
  • Superior Salivatory Nucleus will synapse with _____and _____
  • Inferior Salivatory Nucleus will synapse with ___________
A

Edinger-Westphal = Ciliary Ganglion
Superior Salivatory Nucleus = Pterygopalatine and Submandibular Ganglia
Inferior Salivatory Nucleus = OTIC Ganglion

25
The Anterior Nucleus functions in __________ and __________ ?
The Anterior Nucleus functions in MEMORY and EMOTIONS
26
The Medial Group of Nuclei functions in __________ and ________ ?
The Medial Group of Nuclei functions in MEMORY and BEHAVIOR
27
Lesion of Medial Group of Nuclei?
Frontal Lobotomy
28
Lesion of Ventral Posterior Nucleus?
- Anesthesia | - Thalamic Syndrome
29
_______________ Tracts carry proprioception from lower extremities
Spinocerebellar Tracts
30
Lesion of Nucleus of Spinal Tract of Trigeminal?
Ipsilateral loss of P and T from face
31
Lesion of Chief Sensory Nucleus?
Ipsilateral loss of touch from face
32
Lesion of Mesencephalic Nucleus?
Ipsilateral loss of proprioception from face
33
Ratio of Pre-Post Ganglionic Fibers is 1:10 for ____________ and 1:3 for ____________ ?
1: 10 = Sympathetics 1: 3 = Parasympathetics
34
Primary Motor Cortex is the _____________ Gyrus, Area ___ ?
Primary Motor Cortex is the PRECENTRAL GYRUS, AREA 4
35
Motor Homunculus refers to ________ Gyrus and ______ Lobule?
Motor Homunculus refers to PRECENTRAL GYRUS and PARACENTRAL LOBULE
36
Where is Broca's Area?
Posterior Portion of Inferior Frontal Gyrus
37
The Dorsal Spinocerebellar Tract detects _______________ from the __________ extremities, eventually will synapse with ____________ ?
The Dorsal Spinocerebellar Tract detects CONSCIOUS AND UNCONSCIOUS PROPRIOCEPTION from the LOWER EXTREMITIES, eventually will synapse with NUCLEUS DORSALIS
38
In the Dorsal Spinocerebellar Tract, __________ Fibers synapse with Nucleus Z, and _____________ Fibers enter the Cerebellum via the Inferior Cerebellar Peduncle
In the Dorsal Spinocerebellar Tract, CONSCIOUS PROPRIOCEPTION FIBERS synapse with Nucleus Z, and UNCONSCIOUS PROPRIOCEPTION FIBERS enter the Cerebellum via the Inferior Cerebellar Peduncle
39
The Ventral Spinocerebellar Tract detects ______________ from the __________ extremities ; and synapse with ___________
The Ventral Spinocerebellar Tract detects UNCONSCIOUS PROPRIOCEPTION from the LOWER EXTREMITIES ; and synapse with NUCLEUS PROPRIUS
40
The Nucleus Proprius gives rise to the ___________________ which enters the cerebellum via the ____________________ after it crosses for a second time
The Nucleus Proprius gives rise to the CONTRALATERAL VENTRAL SPINOCEREBELLAR TRACT which enters the Cerebellum via the SUPERIOR CEREBELLAR PEDUNCLES after it crosses for a second time