FINAL Flashcards

1
Q

What is nociceptive pain?

A

Pain resulting from nociceptor activation due to tissue injury and resultant inflammation

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2
Q

What is neuropathic pain?

A

Pain resulting from direct insult to the nerve

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3
Q

How is fast sharp pricking pain transmitted to the spinal cord?

A

Fast sharp pricking pain is transmitted to the spinal cord via myelinated A-delta fibers

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4
Q

How is slow dull pain transmitted to the spinal cord?

A

Slow dull pain is transmitted to the spinal cord via unmyelinated C fibers

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5
Q

Primary Hyperalgesia

A

Sensitization of primary nociceptors after injury/inflammation

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6
Q

Central Hyperalgesia

A

Sensitization of Dorsal Horn Cells after injury

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7
Q

A-delta and C primary afferents synapse with these 3 things:

A
  1. Nucleus Proprius
  2. Pericornual Cells
  3. Substantia Gelitanosa
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8
Q

What are nociceptors?

A

Receptors that respond to noxious stimuli from skin/soft tissue injury

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9
Q

Preganglionic Sympathetics release __________, mediated by

___________ ?

A

Preganglionic Sympathetics release ACETYLCHOLINE, mediated by ACH NICOTONIC RECEPTORS

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10
Q

Preganglionic Parasympathetics release __________, mediated by
___________ ?

A

Preganglionic Parasympathetics release ACH mediated by NICOTONIC ACH RECEPTORS

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11
Q

Postganglionic Sympathetics release ______________, mediated by ____________ ?

A

Postganglionic Sympathetics release NOREPINEPHRINE , mediated by NORADRENERGIC RECEPTORS (alpha 1,2 ; beta 1,2,3)

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12
Q

Postganglionic Parasympathetics release ____________ , mediated by _____________ ?

A
Postganglionic Parasympathetics release ACH, mediated by
MUSCARINIC RECEPTORS (m1, m2, m3)
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13
Q

The Sympathetic and Parasympathetic systems innervate:

A
  1. Cardiac Muscle
  2. Smooth Muscle
  3. Glandular Tissue
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14
Q

Enteric division has greater _________ , mediates ____________ ?

A

Enteric division has greater AUTONOMY , mediates DIGESTIVE REFLEXES

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15
Q

Preganglionic Sympathetics are in the __________ of __________ ?

A

Preganglionic Sympathetics are in the INTERMEDIOLATERAL GRAY of T1-L2

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16
Q

Preganglionic Fibers exit through the __________ ?

A

Ventral Root

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17
Q

Preganglionic Fibers form the ____________ and enter the

____________ ?

A

Preganglionic Fibers form the WHITE RAMI COMMUNICANTES and enter the PARAVERTEBRAL SYMPATHETIC GANGLIA

18
Q

Preganglionic Sympathetic Fibers synapse with the sympathetic chain ganglia at what levels?

A

Same, Lower, and Higher

19
Q

Postganglionic Fibers form the ____________, and enter ______ ?

A

Postganglionic Fibers form the GRAY RAMI COMMUNICANTES and enter SPINAL NERVES

20
Q

How do Postganglionic Sympathetic Fibers from the Cervical, Thoracic, and Lumbar ganglia reach their target?

A

Via Spinal Nerves

21
Q

_____________ Sympathetic Fibers innervate peripheral blood vessels, sweat glands, and arrectores pilorum muscles.

A

Postganglionic Sympathetic Fibers

22
Q

Preganglionic Parasympathetic Cells are found in the __________ , and these Cranial Nerves __________ ?

A

Preganglionic Parasympathetic Cells are found in the INTERMEDIOLATERAL GRAY OF S2-4 and in CN III, VII, IX, X

23
Q

Preganglionic Cells in the brainstem are:

A
  1. Edinger-Westphal Nucleus (III)
  2. Superior Salivatory Nucleus (VII)
  3. Inferior Salivatory Nucleus (IX)
  4. Dorsal Motor Nucleus (X)
24
Q
  • Edinger-Westphal Nucleus will synapse with _____________
  • Superior Salivatory Nucleus will synapse with _____and _____
  • Inferior Salivatory Nucleus will synapse with ___________
A

Edinger-Westphal = Ciliary Ganglion
Superior Salivatory Nucleus = Pterygopalatine and Submandibular Ganglia
Inferior Salivatory Nucleus = OTIC Ganglion

25
Q

The Anterior Nucleus functions in __________ and __________ ?

A

The Anterior Nucleus functions in MEMORY and EMOTIONS

26
Q

The Medial Group of Nuclei functions in __________ and ________ ?

A

The Medial Group of Nuclei functions in MEMORY and BEHAVIOR

27
Q

Lesion of Medial Group of Nuclei?

A

Frontal Lobotomy

28
Q

Lesion of Ventral Posterior Nucleus?

A
  • Anesthesia

- Thalamic Syndrome

29
Q

_______________ Tracts carry proprioception from lower extremities

A

Spinocerebellar Tracts

30
Q

Lesion of Nucleus of Spinal Tract of Trigeminal?

A

Ipsilateral loss of P and T from face

31
Q

Lesion of Chief Sensory Nucleus?

A

Ipsilateral loss of touch from face

32
Q

Lesion of Mesencephalic Nucleus?

A

Ipsilateral loss of proprioception from face

33
Q

Ratio of Pre-Post Ganglionic Fibers is 1:10 for ____________ and
1:3 for ____________ ?

A

1: 10 = Sympathetics
1: 3 = Parasympathetics

34
Q

Primary Motor Cortex is the _____________ Gyrus, Area ___ ?

A

Primary Motor Cortex is the PRECENTRAL GYRUS, AREA 4

35
Q

Motor Homunculus refers to ________ Gyrus and ______ Lobule?

A

Motor Homunculus refers to PRECENTRAL GYRUS and PARACENTRAL LOBULE

36
Q

Where is Broca’s Area?

A

Posterior Portion of Inferior Frontal Gyrus

37
Q

The Dorsal Spinocerebellar Tract detects _______________ from the __________ extremities, eventually will synapse with ____________ ?

A

The Dorsal Spinocerebellar Tract detects CONSCIOUS AND UNCONSCIOUS PROPRIOCEPTION from the LOWER EXTREMITIES, eventually will synapse with NUCLEUS DORSALIS

38
Q

In the Dorsal Spinocerebellar Tract, __________ Fibers synapse with Nucleus Z, and _____________ Fibers enter the Cerebellum via the Inferior Cerebellar Peduncle

A

In the Dorsal Spinocerebellar Tract, CONSCIOUS PROPRIOCEPTION FIBERS synapse with Nucleus Z, and UNCONSCIOUS PROPRIOCEPTION FIBERS enter the Cerebellum via the Inferior Cerebellar Peduncle

39
Q

The Ventral Spinocerebellar Tract detects ______________ from the __________ extremities ; and synapse with ___________

A

The Ventral Spinocerebellar Tract detects UNCONSCIOUS PROPRIOCEPTION from the LOWER EXTREMITIES ; and synapse with NUCLEUS PROPRIUS

40
Q

The Nucleus Proprius gives rise to the ___________________ which enters the cerebellum via the ____________________ after it crosses for a second time

A

The Nucleus Proprius gives rise to the CONTRALATERAL VENTRAL SPINOCEREBELLAR TRACT which enters the Cerebellum via the SUPERIOR CEREBELLAR PEDUNCLES after it crosses for a second time