FINAL Flashcards
What is nociceptive pain?
Pain resulting from nociceptor activation due to tissue injury and resultant inflammation
What is neuropathic pain?
Pain resulting from direct insult to the nerve
How is fast sharp pricking pain transmitted to the spinal cord?
Fast sharp pricking pain is transmitted to the spinal cord via myelinated A-delta fibers
How is slow dull pain transmitted to the spinal cord?
Slow dull pain is transmitted to the spinal cord via unmyelinated C fibers
Primary Hyperalgesia
Sensitization of primary nociceptors after injury/inflammation
Central Hyperalgesia
Sensitization of Dorsal Horn Cells after injury
A-delta and C primary afferents synapse with these 3 things:
- Nucleus Proprius
- Pericornual Cells
- Substantia Gelitanosa
What are nociceptors?
Receptors that respond to noxious stimuli from skin/soft tissue injury
Preganglionic Sympathetics release __________, mediated by
___________ ?
Preganglionic Sympathetics release ACETYLCHOLINE, mediated by ACH NICOTONIC RECEPTORS
Preganglionic Parasympathetics release __________, mediated by
___________ ?
Preganglionic Parasympathetics release ACH mediated by NICOTONIC ACH RECEPTORS
Postganglionic Sympathetics release ______________, mediated by ____________ ?
Postganglionic Sympathetics release NOREPINEPHRINE , mediated by NORADRENERGIC RECEPTORS (alpha 1,2 ; beta 1,2,3)
Postganglionic Parasympathetics release ____________ , mediated by _____________ ?
Postganglionic Parasympathetics release ACH, mediated by MUSCARINIC RECEPTORS (m1, m2, m3)
The Sympathetic and Parasympathetic systems innervate:
- Cardiac Muscle
- Smooth Muscle
- Glandular Tissue
Enteric division has greater _________ , mediates ____________ ?
Enteric division has greater AUTONOMY , mediates DIGESTIVE REFLEXES
Preganglionic Sympathetics are in the __________ of __________ ?
Preganglionic Sympathetics are in the INTERMEDIOLATERAL GRAY of T1-L2
Preganglionic Fibers exit through the __________ ?
Ventral Root