FINAL Flashcards
What is nociceptive pain?
Pain resulting from nociceptor activation due to tissue injury and resultant inflammation
What is neuropathic pain?
Pain resulting from direct insult to the nerve
How is fast sharp pricking pain transmitted to the spinal cord?
Fast sharp pricking pain is transmitted to the spinal cord via myelinated A-delta fibers
How is slow dull pain transmitted to the spinal cord?
Slow dull pain is transmitted to the spinal cord via unmyelinated C fibers
Primary Hyperalgesia
Sensitization of primary nociceptors after injury/inflammation
Central Hyperalgesia
Sensitization of Dorsal Horn Cells after injury
A-delta and C primary afferents synapse with these 3 things:
- Nucleus Proprius
- Pericornual Cells
- Substantia Gelitanosa
What are nociceptors?
Receptors that respond to noxious stimuli from skin/soft tissue injury
Preganglionic Sympathetics release __________, mediated by
___________ ?
Preganglionic Sympathetics release ACETYLCHOLINE, mediated by ACH NICOTONIC RECEPTORS
Preganglionic Parasympathetics release __________, mediated by
___________ ?
Preganglionic Parasympathetics release ACH mediated by NICOTONIC ACH RECEPTORS
Postganglionic Sympathetics release ______________, mediated by ____________ ?
Postganglionic Sympathetics release NOREPINEPHRINE , mediated by NORADRENERGIC RECEPTORS (alpha 1,2 ; beta 1,2,3)
Postganglionic Parasympathetics release ____________ , mediated by _____________ ?
Postganglionic Parasympathetics release ACH, mediated by MUSCARINIC RECEPTORS (m1, m2, m3)
The Sympathetic and Parasympathetic systems innervate:
- Cardiac Muscle
- Smooth Muscle
- Glandular Tissue
Enteric division has greater _________ , mediates ____________ ?
Enteric division has greater AUTONOMY , mediates DIGESTIVE REFLEXES
Preganglionic Sympathetics are in the __________ of __________ ?
Preganglionic Sympathetics are in the INTERMEDIOLATERAL GRAY of T1-L2
Preganglionic Fibers exit through the __________ ?
Ventral Root
Preganglionic Fibers form the ____________ and enter the
____________ ?
Preganglionic Fibers form the WHITE RAMI COMMUNICANTES and enter the PARAVERTEBRAL SYMPATHETIC GANGLIA
Preganglionic Sympathetic Fibers synapse with the sympathetic chain ganglia at what levels?
Same, Lower, and Higher
Postganglionic Fibers form the ____________, and enter ______ ?
Postganglionic Fibers form the GRAY RAMI COMMUNICANTES and enter SPINAL NERVES
How do Postganglionic Sympathetic Fibers from the Cervical, Thoracic, and Lumbar ganglia reach their target?
Via Spinal Nerves
_____________ Sympathetic Fibers innervate peripheral blood vessels, sweat glands, and arrectores pilorum muscles.
Postganglionic Sympathetic Fibers
Preganglionic Parasympathetic Cells are found in the __________ , and these Cranial Nerves __________ ?
Preganglionic Parasympathetic Cells are found in the INTERMEDIOLATERAL GRAY OF S2-4 and in CN III, VII, IX, X
Preganglionic Cells in the brainstem are:
- Edinger-Westphal Nucleus (III)
- Superior Salivatory Nucleus (VII)
- Inferior Salivatory Nucleus (IX)
- Dorsal Motor Nucleus (X)
- Edinger-Westphal Nucleus will synapse with _____________
- Superior Salivatory Nucleus will synapse with _____and _____
- Inferior Salivatory Nucleus will synapse with ___________
Edinger-Westphal = Ciliary Ganglion
Superior Salivatory Nucleus = Pterygopalatine and Submandibular Ganglia
Inferior Salivatory Nucleus = OTIC Ganglion