Final 3 Flashcards

1
Q

What type of cells do you see in aspiration pneumonia?

A

Giant cells

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2
Q

Pontiac fever

A

Legionella

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3
Q

Foamy macrophages filling alveoli

A

Legionella

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4
Q

Hyponatremia, neurologic symptoms, & abdominal pain are suggestive of what?

A

Legionella

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5
Q

What is like a GNB but has no cell wall?

A

mycoplasma

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5
Q

Has reticulate body, elementary body life cycle

A

chlamydia

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6
Q

Cell mediated immunity is defective in what?

A

AIDS
Lymphomas
Organ transplant recipients
Pts on corticosteroid therapy

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7
Q

Bilateral infiltrates in perihilar region (butterfly)

A

Pneumocystis jirovecci

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8
Q

Modified acid fast stain

A

for Nocardia

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9
Q

2 types of humoral immune deficiency

A

Hypogammaglobulinemia

Asplenia

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10
Q

Humoral immune deficiency –> what pathogens?

A

Encapsulated bacteria:
Strep pneumoniae
Haemophilus influenzae
Neisseria meningiditis

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11
Q

Areas of innate immunity deficiency:

A

Neutrophils (deficiency or defect)
Complement
Antimicrobial peptides

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12
Q

What causes a neutrophil defect?

A

chronic granulomatous disease

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13
Q

Mycobacterium stain

A

Ziehl-Neelsen acid fast stain

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14
Q

Caridnal findings of leprosy

A

infiltrative skin lesions
hypoesthesia
peripheral neuropathy

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15
Q

Dimorphic fungi

A

yeasts at body temp

Hyphal form in nature

16
Q

3 most common causes of pleural effusion

A

CHF - 500k
Bacterial pneumonia - 300k
Cancer - 200k

17
Q

Pleural effusion physical exam findings

A

Reduced tactile fremitus
dull or flat note on percussion
diminished or absent breath sounds on ascultation

18
Q

SARS is caused by which virus?

A

Coronavirus

19
Q

What can resemble strep throat?

A

Viral pharyngitis with adenovrius

20
Q

Flu symptoms

A

Abrupt onset of fever
severe headache
muscle ache
extreme exhaustion

21
Q

Adamantane adverse reactions

A

Anticholinergic (dry mouth, pupillary dilation, toxic)

Central nervous system toxicity

22
Q

Acyclovir adverse reaction

A

generally well tolerated

reversible renal dysfuntino in 5% treated with high doses for HSV encephalitis due to tubular precipitation of acyclovir

22
Q

Cidofovir adverse effects

A

nephrotoxicity

drug is concentrated 100 fold in renal tubular cell

23
Q

Foscarnet adverse reactions

A

impaired renal function, generally reversible, is the most common dose limiting side effect
anemia is seen in 20-50% of pts

23
Q

Erythromycin adverse effects

A

GI
hearing loss
possible prolongation of QT & torsade de pointe
thrombophlebitis

24
Q

Tetracycline elimination

A

All kidney, except doxycycline

25
Q

Which are the anti-pseudomonal beta lactams?

A
piperacillin
aztreonam
carbapenem
cefipime
ceftazidime
26
Q

3 most common malignancies that cause pleural effusion

A

breast, lung, lymphoma

27
Q

Modified wells, levels:

A

0-1 –> low
2-6 –> moderate
7 & up –> high

28
Q

Wells criteria, levels

A

0 - low
1-2 - moderate
3 & up - high

29
Q

Which are the anti-pseudomonal beta lactams?

A
piperacillin
aztreonam
carbapenem
cefipime
ceftazidime
30
Q

3 most common malignancies that cause pleural effusion

A

breast, lung, lymphoma

31
Q

Modified wells, levels:

A

0-1 –> low
2-6 –> moderate
7 & up –> high

32
Q

Wells criteria, levels

A

0 - low
1-2 - moderate
3 & up - high