Final 2 Flashcards
Mycoplasma diagnosis
IgM serology
Lancet shaped diplococci
Strep pneumoniae
What is HPIV-1 and HPIV-2 associated with?
croup
What is HPIV-3 associated with?
bronchiolitis & pneumonia
Orthomyxovirus v. Paramyxovirus
Ortho - flu
paramyxovirus - HPIV & RSV
Antiviral activity of ribavirin
RSV & Hep C
Adverse reactions of ribavirin
aerosolized form –> bronchospasm & reversible pulmonary deterioration
Systemic form –> bone marrow toxicity, hemolysis, anemia
What are the 3 CMV drugs?
Ganciclovir
Cidofovir
Foscarnet
Causes of transudative pleural effusion
CHF (most common total cause of pleural effusion)
Hypoalbuminemia (cirrhosis)
nephrotic syndrome
protein losing enteropathy
Adverse effects of tetracyclines
Skin
bone & teeth –> avoid in children
GI, liver, renal
vertigo, esp with minocycline
Mechanism of action of quinolones:
inhibit DNA gyrase & topoisomerase IV
bactericidal
Common toxicity of all 2nd gen quinolones
Prolonged QT interval
use with caution with agents that prolong the QT interval
Linezolid adverse effects
thrombocytopenia
neutropenia
abnormal LFTs
serotonin syndrome with hyperpyrexia
Symptoms for lobar v. interstital pneumonia
Lobar - cough productive of colored sputum
Interstitial - Dry, nonproductive cough