Final 2 Flashcards

1
Q

Mycoplasma diagnosis

A

IgM serology

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2
Q

Lancet shaped diplococci

A

Strep pneumoniae

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3
Q

What is HPIV-1 and HPIV-2 associated with?

A

croup

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4
Q

What is HPIV-3 associated with?

A

bronchiolitis & pneumonia

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5
Q

Orthomyxovirus v. Paramyxovirus

A

Ortho - flu

paramyxovirus - HPIV & RSV

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6
Q

Antiviral activity of ribavirin

A

RSV & Hep C

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7
Q

Adverse reactions of ribavirin

A

aerosolized form –> bronchospasm & reversible pulmonary deterioration
Systemic form –> bone marrow toxicity, hemolysis, anemia

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8
Q

What are the 3 CMV drugs?

A

Ganciclovir
Cidofovir
Foscarnet

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9
Q

Causes of transudative pleural effusion

A

CHF (most common total cause of pleural effusion)
Hypoalbuminemia (cirrhosis)
nephrotic syndrome
protein losing enteropathy

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10
Q

Adverse effects of tetracyclines

A

Skin
bone & teeth –> avoid in children
GI, liver, renal
vertigo, esp with minocycline

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11
Q

Mechanism of action of quinolones:

A

inhibit DNA gyrase & topoisomerase IV

bactericidal

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12
Q

Common toxicity of all 2nd gen quinolones

A

Prolonged QT interval

use with caution with agents that prolong the QT interval

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13
Q

Linezolid adverse effects

A

thrombocytopenia
neutropenia
abnormal LFTs
serotonin syndrome with hyperpyrexia

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14
Q

Symptoms for lobar v. interstital pneumonia

A

Lobar - cough productive of colored sputum

Interstitial - Dry, nonproductive cough

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