Final Flashcards
Chronic transmural inflammatory disease of the distal ileum & colon. Rectum is not involved. Pt has perianal fistulas or abscesses & non-bloody diarrhea. Smoking increases the likelihood
Crohn’s Disease AKA Regional Enteritis; Granulomatous Ileitis, Ileocolitis
Discontinuous lesions assoc. w/ Crohn’s Disease are AKA?
Skip lesions
Chronic inflammatory disease arising in the mucosa & submucosa of the colon. Smoking decreases risk.
Ulcerative colitis
What is the M/C clinical presentation of Ulcerative colitis?
Bloody Diarrhea
Diverticula M/C’ly occur in what part of the colon?
Sigmoid colon
Diverticula that contain all layers of the affected area are called what?
True diverticula
False or pseudo diverticula have mucosa only going through what layer?
Muscular layer
Multiple diverticula in the colon is called what? Typically asymptomatic but can become inflamed & bleed
Diverticulosis
What individuals are typically affected by diverticulosis?
> 40 yr old. Individuals w/ a low fiber diet
Inflammation of the diverticula is called what?
Diverticulitis
What % of diverticula that become inflamed resolve on their own?
75%
This is a congenital anomaly in distal ileum w/i 100cm (3ft) of ileocecal valve that occurs M/C’ly in older children. Represents persistent prox. end of yolk sac, sometimes becomes attached to inside of umbilicus. M/C diverticulum in the small bowel
Meckel’s Diverticulum
Acute longitudinal tear or ulcer in squamous epithelium of anal canal from large stool passage w/ secondary infection
Anal fissures
Anorectal abscesses are M/C’ly caused by what?
Bacterial infection
Tube-like tract w/ one opening in the anal canal & the other usually in the perianal skin. Assoc. w/ Crohns
Anorectal Fistula
Episodic rectal pain lasting <20mins d/t spasm of levator ani muscle
Levator Syndrome
Acute abscess or chronic drainage sinus in the sacrococcygeal region (cyst formation under skin)
Pilonidal Disease
Inflammation of anus & the distal rectal mucosa from infection (STD or bacterial), IBD or radiation
Proctitis
What is the M/C etiology of proctitis?
STD’s
Proctitis may develop d/t long term use of what type of medication?
Antibiotics
Painless protrusion of rectum thru the anus
Rectal prolapse
What is the M/C benign tumor of the esophagus?
Leiomyoma (excellent prognosis for recovery)
What are the 2 M/C malignant tumors of the esophagus?
Squamous cell carcinoma (M/C)
Adenocarcinoma (2nd M/C)
What are features of squamous cell carcinoma?
Caused by alcohol/tobacco
M/C occurrence in Asia & South Africa
M/C in African Americans
What are features of adenocarcinoma?
Caused by smoking (but not alcohol)
Seen in distal esophagus (Barrett’s)
50% Caucasian esophageal cancers
M/C’ly affects males
What is the 2nd M/C cancer worldwide?
Stomach cancer
What bacteria plays a significant role in stomach cancer?
H. pylori
Type of cancer that makes up 95% of all stomach cancers?
Gastric adenocarcinoma
What sign is not commonly assoc. w/ small bowel tumors?
Polyps
Polyps of the colon & the rectum are M/C’ly seen in what part?
Sigmoid area
Any mass of tissue that arises from the bowel wall & protrudes into the lumen is known as what?
Polyps
Primary adenocarcinoma of the pancreas M/C’ly occurs in what part of the pancreas?
Pancreatic head (80%)
What two things ARE NOT risk factors for primary adenocarcinoma in the pancreas?
Alcohol
Caffeine
Gastrin-producing tumor located in pancreas or duodenal walls. Gastric acid hyper-secretion leads to peptic ulcer
Zollinger-Ellison Syndrome AKA Z-E syndrome, Gastrinoma
What is the most metabolically complex organ in the body?
Liver
Free fluid in the peritoneal cavity M/C’ly caused by portal hypertension from liver disease is called what?
Ascites
Yellowing of the skin, sclera & other tissues caused by excess circulating hyperbilirubinemia
Jaundice
What are s/s assoc. w/ jaundice?
Nausea
Vomiting
Dark urine
Conjugation (4th step) during bilirubin metabolism allows what to happen to bilirubin?
Becomes water soluble and can pass through kidneys
Syndrome that causes impaired excretion of bilirubin. Liver itself is healthy but dark
Dubin-Johnson Syndrome
Rare & severe unconjugated hyperbilirubinemia. Most pts die before 1 yr of age
Crigler-Najjar Syndrome
What is consider normal pressure in the portal system?
5-10mmHg
What are the 2 M/C etiologies for portal hypertension?
Liver cirrhosis
Hepatic Vascular Abnormalities (increased resistance to blood flow from ds w/i liver)
Alcohol causes liver injury that can progress to what 3 pathologies?
Fatty liver
Alcoholic hepatitis
Cirrhosis of liver