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Parasitology > Filarial Worms > Flashcards

Filarial Worms Flashcards

1
Q

Secretory cells of C. philippinensis

A

Stichocyte

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2
Q

Esophageal structure of C. philippinensis

A

Stichosome

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3
Q

C. philippinensis

Adult male

A

Chitinized spicule protected by unspined sheath, caudal alae

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4
Q

C. philippinensis

Adult typical female

A

Oviparous

Uterus with 8-10 eggs arranged in a single row

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5
Q

C. philippinensis

Adult atypical female

A

Oviviparous

Uterus with 40-45 eggs arranged in 2-3 rows

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6
Q

C. philippinensis

MOT

A

Ingestion of infected fish

Autoinfection

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7
Q

C. philippinensis

Typical egg

A

Segmented with thick striated shell and flattened bipolar plugs
Peanut / guitar shaped

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8
Q

C. philippinensis

Atypical egg

A

Multisegmented or embryonated with thin shell and NO polo plugs

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9
Q

C. philippinensis

Pathology

A

MYSTERY DISEASE
Borborygmus (gurgling sound of stomach)
Malabsorption syndrome of fats and sugars
Diarrhea: protein loss, electrolyte loss, dehydration, weight loss
High IgE level

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10
Q

C. philippinensis

IS

A

Larva

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11
Q

C. philippinensis

IH

A

“Ipon” (Sicyopterus sp.)
“Bagsang” (Ambassis miops)
“Birut” (Eliotris melanosoma)
“Buctu” (Chonoporus melanocephalus)

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12
Q

C. philippinensis

Habitat

A

Small intestine

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13
Q

C. philippinensis

Morphology

A

Threadlike worm

Relative of trichuris

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14
Q

C. philippinensis

Lab diagnosis

A
  1. Stool exam- eggs or larva
    a. DFS
    b. AECT, FECT, MIFCT
  2. Dupdenal aspiration
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15
Q

C. philippinensis

Treatment

A

ALBENDAZOLE
Mebendazole
Electrolyte replacement
High protein test

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16
Q

Filarial worm

FH

A

Man

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17
Q

Filarial worm

DS

A

Microfilaria

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18
Q

Filarial worm

IS

A 
Filiform larva (L3) / 
Filariform larva
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19
Q

Filarial worm

MOT

A

Arthropod-borne

Bite of an infected vector

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20
Q

Filarial worm

Morphology

A

Threadlike worms

21
Q

Filarial worm

Adult male

A

Two spicules

22
Q

Filarial worm

Adult female

A

Viviparous

Narrow tail end and pointed

23
Q

Filarial worm

Pathology 1

A

LYMPHATIC FILARIASIS
(Caused mainly by adult worms)
Elephantiasis

24
Q

Filarial worm

Pathology 2

A

MEYERS-KOUWENAAR’S SYNDROME

Lymphadenopathy + hypereosinophilia

25
Q

Filarial worm

Pathology 3

A

WEINGARTEN’S SYNDROME

Tropical Pulmonary Eosinophilia resembling bronchial asthma

26
Q

Filarial worm

Pathology 4

A

EXPATRIATE SYNDROME

Immunologic hypersensitivity to mature worms

27
Q

Filarial worm

Lab dignosis

A
  1. BLOOD SMEAR (wet or thick)
  2. MEMBRANE FILTRATION TECHNIQUE
    - heparinized blood
    - nucleopore filter (5 um) in a Swinney adapter
  3. KNOTT’S CONCENTRATION TECHNIQUE
    - 1 mL blood + 10 mL 2% formalin (lyses RBCS)
28
Q

Filarial worm
Lab Diagnosis
Miscellaneous

A

Immunochromatography
Antigen detection for circulating filarial antigen (CFA)
PCR
Ultrasonography

29
Q

Filarial worm

Treatment

A

Diethyl Carbamazine (DEC)
Ivermectin (Stromeclol)
Albendazole

30
Q

Wuchereria bancrofti

Common name

A

Bancroft’s filarial worm

31
Q

Wuchereria bancrofti

Vector

A

Anopheles minimus flavirostris
Aedes poecilus
Culex quiquefasciatus

32
Q

Wuchereria bancrofti

Habitat

A

Lower lymph gland

33
Q

Wuchereria bancrofti

Periodicity

A

Nocturnal
10pm-2pm (peak time)
8pm-4am

34
Q

Wuchereria bancrofti
Sheated Microfilaria
Cephalic space : breadth ratio

A

1:1

35
Q

Wuchereria bancrofti
Sheated Microfilaria
Sheath affinity to giemsa

A

Unstained

36
Q

Wuchereria bancrofti
Sheated Microfilaria
Body nuclei

A

Discrete and separate

37
Q

Wuchereria bancrofti
Sheated Microfilaria
Nucleus on tail end

A

None

38
Q

Wuchereria bancrofti
Sheated Microfilaria
Appearance in blood film

A

Graceful / smooth curve

39
Q

Brugia malayi

Common name

A

Malayan filarial worm

40
Q

Brugia malayi

Vector

A

Mansonia bonnae

Mansonia uniformis

41
Q

Brugia malayi

Habitat

A

Upper lymph gland

42
Q

Brugia malayi

Periodicity

A

Nocturnal

Subperiodic

43
Q

Brugia malayi
Sheathed microfilaria
Cephalic space : breadth ratio

A

2:1

44
Q

Brugia malayi
Sheathed microfilaria
Sheath affinity to giemsa

A

Pink

45
Q

Brugia malayi
Sheathed microfilaria
Body nuclei

A

Big and overlapping /

Confluent

46
Q

Brugia malayi
Sheathed microfilaria
Nucleus on tail end

A

Two

47
Q

Brugia malayi
Sheathed microfilaria
Appearance in blood film

A

Kinky and angular curve

48
Q

Capillaria philippinensis

common name

A

Pudoc worm

Parasitology (8 decks)

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