fibroids Flashcards

1
Q

what are fibroids?

A

benign tumours of smooth muscle of uterus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what is another name for fibroids?

A
  • Also called uterine leiomyomas
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what do fibroids grow in response to?

A
  • Oestrogen sensitive and grow in response to oestrogen
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what is the prevalance of fibroids?

A

very common in older reproductive years
- More common in black women

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what are the 4 types of fibroids?

A

intramural
subserosal
submucosal
pedunculated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

where is an intramural fibroid located?

A

within myometrium and change shape and distort uterus as they grow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

where is subserosal fibroids located?

A

just below outer layer and grow outwards  grow very large and fill abdo cavity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

where are submucosal fibroids located?

A

just below lining of uterus – endometrium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

how would fibroids present?

A

often asymptomatic
- Menorrhagia – most frequent symptom
- Prolonged menstruation - >7days
- Abdo pain – worse during menstruation
- Bloating/ feeling full due to pelvic pressure
- Deep dyspareunia – pain during intercourse

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what can be seen within abdo/ bimanual exam for fibroids?

A

reveal palpable pelvic mass/ enlarged firm non-tender uterus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what is first line investigations for fibroids?

A

assessing for submucosal fibroids in those presenting with heavy bleeding

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

when would pelvic US be indicated for investigating fibroids?

A

: for larger fibroids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

when would MRI be indicated for investigating fibroids?

A

maybe used prior to surgery for gain more info

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

how would you manage <3cm fibroids?

A

same management as menorrhagia
mirena
symptomatic
COCP
cyclical oral progesterone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

when could a mirena coil be used within fibroids?

A

if no distortion of uterus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what symptomatic management can be used in fibroids

A

NSAID and tranexamic acid

17
Q

what medical pills can be used to help smaller fibroids?

A
  • Combined oral contraceptive
  • Cyclical oral progesterone’s
18
Q

name a cyclical progesterone?

A

norethisterone

19
Q

what surgical management can be put in place for smaller fibroids that cause excessive bleeding?

A
  • Endometrial ablation
  • Resection of submucosal fibroids during hysteroscopy
  • Hysterectomy
20
Q

when should fibroids be referred to gynae?

A

excessive bleeeding - not PC controlled
>3cm

21
Q

what medical management can be used to help with larger fibroids?

A
  • Medical: Mirena coil: if no distortion of uterus
  • Symptomatic : NSAID and tranexamic acid
  • Combined oral contraceptive
  • Cyclical oral progesterone’s
22
Q

what surgical options are there for larger fibroids >3cm?

A

uterine artery embolisation
- Myomectomy
- Hysterectomy

23
Q

what is a uterine artery embolisation?

A

starves fibroid of oxygen causing it to shrink

24
Q

what medical management can be given prior to fibroid surgery?

A

GnRH agonists eg goserelin

25
how does GnRH agonists help within fibroid surgery manangement?
may help shrink fibroids prior to surgery - Reduce amount of oestrogen - Only short term
26
what complications can be seen within fibroids?
- Heave bleeding  IDA - Reduced fertility - Pregnancy complications – miscarriages, premature labour, obstructive delivery - Constipation - Urinary outflow obstruction and UTI - Red generation of fibroid - Torsion - Malignant change to leiomyosarcoma  very rare <1%
27
what is red generation of fibroid?
ischaemia, infarction and necrosis of fibroid likely to disrupted blood supply
28
when are red generation fibroids most likely?
- More likely in big fibroids >5cm in 2nd/3rd trimester - Pregnancy: fibroids grow  outgrows its blood supply and becomes ischaemic , may be due to uterus changing shape
29
how would red generation fibroids present?
pregnant women: severe abdo pain, low grade fever, tachycardia, vomiting
30
how do you manage red generation fibroids?
supportive, rest, fluids and analgesia
31