FIBRINOLYTICS Flashcards

1
Q

Indications for alteplase

A

Acute MI
Acute ischemic stroke
Pulmonary embolism

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2
Q

Mechanism of action of alteplase

A

Alteplase is a recombinant tissue plasminogen activator (rt-PA) that converts plasminogen to plasmin in a fibrin-dependent process.

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3
Q

Maximum dose of alteplase

A

MI- 100mg
Ischemic stroke- 90mg
Pulmonary embolism - 100mg

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