FIBRINOLYTICS Flashcards
1
Q
Indications for alteplase
A
Acute MI
Acute ischemic stroke
Pulmonary embolism
2
Q
Mechanism of action of alteplase
A
Alteplase is a recombinant tissue plasminogen activator (rt-PA) that converts plasminogen to plasmin in a fibrin-dependent process.
3
Q
Maximum dose of alteplase
A
MI- 100mg
Ischemic stroke- 90mg
Pulmonary embolism - 100mg