Fever DSA Flashcards

1
Q

Range for fever Dx

A

Above 100.9 F or 37.8 C

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2
Q

Night sweats are caused by…

A

Exaggeration of normal circadian temperature rhythm

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3
Q

What molecules are responsible for fever? Where do they act? What does it produce?

A

Endogenous pyrogens act at the hypothalamus and lead to an increase in local PGE2, monoamines, Na+, Ca++, etc.

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4
Q

3 endogenous pyrogens causing fever

A

IL-1
TNF
INF-alpha

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5
Q

What is different between TNF and IL-1?

A

TNF does NOT activate WBCs

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6
Q

Hyperthermia definition

A

An elevation in body temperature due to loss of homeostatic mechanisms and inability to increase heat loss in response to environmental heat, as in heat stroke.

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7
Q

Fever of unknown origin (FUO)

A

Fever lasting 3 wks or more with temps exceeding 38.3 C (100.9 F) with no Dx despite 1 wk of clinical investigation

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8
Q

Most common cause of fever in older patients…

A

Infection in RT, UT with skin and soft tissue

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9
Q

4 common causes of fever

A

Infection
AI dz
CNS dz
Malignancy

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10
Q

Drug fever definition

A

Fever coinciding w/ administration of a drug and disappearing after d/c of the drug, when no other cause for the fever is evident after careful exam/workup

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11
Q

Best tools for determining body temp (2)

Greatest variability is with what tool?

A

Electronic and infrared thermometers

Tympanic thermometer

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12
Q

In patients with fever, the best predictors of bacteremia are the patient’s…

A

Underlying diseases (renal failure, trauma, etc.)

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13
Q

Presence of shaking in a pt. w/ fever increases the probability of…

A

Bacteremia

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14
Q

Most common infectious causes of FUO (2)

A

Tb

Intra-abdominal abscesses

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15
Q

Most common malignancies causing FUO (2)

A

Hodgkin’s or non-Hodgkin’s lymphoma

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16
Q

Alarm symptoms associated with fever; if present, consider:

Fever > 105.8 F
Rash
Mental status change
Dizziness/LHness
Recent chemo
SOB/CP
A

Fever > 105.8 F: CNS infection, NMS, heat stroke
Rash: Meningitis, sepsis, Rickettsia, endocarditis
Mental status change: same as rash
Dizziness/LHness: Septic shock, adrenal insufficiency, PE
Recent chemo: nosocomial infection w/ neutrophils
SOB/CP: PE, pneumonia, empyema

17
Q

Causes of IE

A

Historically, been associated w/ heart valve damaged by RHD

Currently, healthcare contact and IVD is most common

18
Q

To Dx IE, the cornerstone of diagnosis of endocarditis is…

What else is helpful?

A

Blood cultures

Transesophageal echo

19
Q

Presenttation of endocarditis is…

When pts. who present ill, toxic or septic demand…

A

Vast in variability

Urgent treatment and workup

20
Q

Most common cause of HF with reduced EF is…

A

CAD (reduced EF -> LV dilation)

21
Q

Most common cause of HF with preserved EF is…

A

HTN w/ LVH

22
Q

S3 and S4 gallops are associated with which parts of the cardiac cycle?

A

S3 - systolic HF

S4 - diastolic HF

23
Q

What is the primary cause of myocarditis?

What causes secondary myocarditis?

A

Acute viral infection or post-viral immune respsone

Inflamation from non-viral pathogens, meds, chemicals, inflammatory diseases, etc.

24
Q

What kind of CP is common in myocarditis?

A

Pleural-pericardial CP

25
Q

Exam of myocarditis reveals…

A

Tachycardia
Gallop rhythm
Other evidence of HF or conduction defects

26
Q

ECG of myocarditis shows…

It might mimic…

ECG features that suggest a higher rate of death or cardiac transplantations…

A

Sinus tachycardia
Intraventricular conduction abnormalities

Might mimic acute MI w/ ST changes, positive cardiac markers and regional wall motion abnormalities

Q waves or LBBB

27
Q

Confirmation of myocarditis requires:

What is insensitive?

A

Histology/Bx

Labs (troponins, CK-MB)

28
Q

Presenting SX of microscopic polyangiitis

A
Purpura
Macules
Vesicles
Bullae
Urticaria