FETAL TERATOGENS Flashcards

1
Q

any factor, chemical or physical, that adversely affects the fertilized ovum, embryo, or fetus.

A

TERATOGENS

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2
Q

FETAL TERATOGENS

A
  1. Maternal Infections/Diseases
  2. Potentially Teratogenic Vaccines
  3. Teratogenic Drugs
  4. Alcohol
  5. Cigarettes
  6. Environmental Teratogens
  7. Maternal Stress
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3
Q

Factors influence the amount of damage a teratogen can cause:

A
  1. Strength of the teratogen
  2. The timing of the teratogenic insult
  3. Teratogen’s affinity for specific tissue
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4
Q

TORCH SCREEN

A

Toxoplasmosis
Other infections (Hep.B & HIV)
Rubella
Cytomegalovirus
Herpes Simples Virus

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5
Q

a protozoan infection, is spread most commonly through contact with uncooked meat, although it may also be contracted through handling cat stool in soil or cat litter.

A

Toxoplasmosis

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6
Q

o Women can help prevent exposure by thorough handwashing before eating and
avoiding crowds of young children at daycare or nursery settings.
• transmitted from person to person by droplet infection

A

Cytomegalovirus (CMV)

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7
Q

• The virus in the mother’s bloodstream (viremia) crosses the placenta to the fetus IF genital lesions are present at the time of birth, however, a fetus may contract the virus from direct exposure during birth.

A

Herpes Simplex Virus (Genital Herpes Infection)

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8
Q

Several infections are not teratogenic to a fetus during pregnancy but are harmful if they are present at the time of birth.

A

– Gonorrhea,
– candidiasis,
– Chlamydia,
– Streptococcus B
– hepatitis B infections

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9
Q

– once liberally prescribed for morning sickness
– causes amelia or phocomelia (total or partial absence of extremities) in 100% of instances when taken between the 34th and 45th day of pregnancy.

A

Thalidomide

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10
Q

– a drug taken by both men and women to restore hair growth
– can cause fetal deformities

A

Minoxidil (Rogaine)

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11
Q

causing intrauterine growth restriction (IUGR)

A

Narcotics

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12
Q

• craniofacial deformity including short palpebral fissures,
• thin upper lip
• upturned nose

A

Fetal Alcohol Syndrome (FAS)

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13
Q

• cause fetal growth restriction.
• fetus may be at greater risk for being stillborn
• after birth, may be at greater risk than others for sudden infant death syndrome.
• Low birth weight in infants

A

Teratogenicity of Cigarette

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14
Q

washing children’s hair with a shampoo such as lindane (Kwell) to remove lice should be limited to two exposures because of potential toxicity.

A

Environmental Teratogens

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