Fertility Control Flashcards

1
Q

These are locally active devices preventing entry of sperm in through the cervix, thus preventing pregnancy.

A

BARRIER-SPERMICIDAL METHODS

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2
Q

BARRIER-SPERMICIDAL METHODS Advanatges

A

Barrier methods become increasingly effective with advancing age and the associated natural decline in fertility.

They do protect against some STDs.

They do not have systemic
side effects.

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3
Q

Failure rate of BARRIER-SPERMICIDAL METHODS

A

approaches 20%.

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4
Q

They are the most common barrier contraceptive method used.

A

Condoms

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5
Q

This is a dome-shaped device placed in the anterior and posterior vaginal fornices holding spermicidal jelly against the cervix. It can be placed an hour before intercourse.

A

Vaginal diaphragm

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6
Q

Disadv of Vaginal diaphragm

A

Individual fitting is required. If too large a size is used, it can result in urinary retention.

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7
Q

The active ingredient is nonoxynol-9, a surface-active agent that disrupts
cell membranes, thus the possible side effect of genital membrane irritation

A

Spermicides.

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8
Q

These include inhibition of the midcycle luteinizing hormone (LH) surge, thus preventing ovulation;

alteration of cervical mucus making it thick and viscid, thus retarding sperm penetration; and alteration of endometrium inhibiting blastocyst implantation

A

STEROID CONTRACEPTION

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9
Q

Mechanism of Action of Steroid Contraception

Pituitary _____
Ovary_______
Endometrium_____
Cervix ______

A

↓ LH surge

↓ ovulation

Atrophy

Hostile mucus

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10
Q

Estrogen effect of steroid hormones

 1
2
3
4
5
A

fluid retention from decreased sodium
excretion;

accelerated development of cholelithiasis;

increase in hepatic protein production

healthy lipid profile changes

and increased venous and arterial thrombosis

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11
Q

What hepatic proteins are increased with estrogenic effects of steroid hormones

A

(e.g., coagulation factors, carrier proteins, angiotensinogen);

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12
Q

Lipid changes of estrogen

A

(increase in high-density lipoproteins [HDL]; decrease in low-density lipoproteins [LDL]);

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13
Q

Progestin-Mediated Metabolic Effects of steroid hormones

A

These include mood changes and depression from decreased serotonin levels; androgenic effects (e.g., weight gain, acne); and unhealthy lipid profile changes (decreased HDL, increased LDL).

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14
Q

Absolute Contraindications of steroid hormones

A

acute liver disease; history of vascular
disease cerebrovascular accident
[CVA], systemic lupus erythematosus [SLE]); hormonally dependent cancer (e.g., breast);
smoker ≥35; uncontrolled hypertension; migraines with aura; diabetes mellitus with vascular disease; and known thrombophilias

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15
Q

Relative Contraindications of steroid hormones.

A

These include migraine headaches, depression, diabetes mellitus,
chronic hypertension, and hyperlipidemia

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16
Q

Noncontraceptive Benefits of steroid hormones

A

These include decreased ovarian and endometrial cancer; decreased dysmenorrhea and dysfunctional uterine bleeding; and decreased PID and ectopic
pregnancy.

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17
Q

Noncontraceptive Benefits of steroid hormones usually from what component

A

Mostly Progestin Component

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18
Q

These contain both an estrogen and a progestin. They are administered
most commonly in one of two ways: daily with 21 days on and 7 days off or daily 24 days on
and 4 days off

A

Combination OCPs

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19
Q

COCP

When “off” the hormones, _____will occur

A

withdrawal bleeding

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20
Q

COCP failure rate

A

Failure rate is 2% with ideal use.

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21
Q

A unique combination of OCP (YAZ) reduces severe PMDD symptoms by 50%. It contains______ and a new progestin, _____. The dosing is 24 days of active pills then 4 days of placebo, rather than the traditional 21 days

A

ethynyl estradiol

drospirenone

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22
Q

Marketed under the trade name of NuvaRing, this device, inserted into the vagina, contains both an estrogen and a progestin. It is removed after 3 weeks for 1 week to allow for a withdrawal bleed.

A

Combination Vaginal Ring

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23
Q

Combination Vaginal Ring failure rate

A

2%

24
Q

Marketed under the trade name of Ortho Evra, this patch contains both an estrogen and a progestin. A patch is replaced every week for 3 weeks then removed for 1
week to allow for a withdrawal bleed.

A

Transdermal Skin Patch

25
Q

They contain only progestins and are sometimes called the “minipill.”

They need to be taken daily and continuously.

A frequent side effect is break-through bleeding.

A

POP

26
Q

POP failure rate

A

Failure rate is 3% with ideal use.

27
Q

Marketed under the trade name of Depo-Provera, this is an IM injection of depo-medroxyprogesterone acetate (DMPA). The slow release allows administration
only every 3 months.

A

Progestin-Only Injectable

28
Q

SE of DMPA

A

A frequent side effect is break-through bleeding. Other side effects are prolonged time for fertility return and decreased bone mineral density

29
Q

Failure rate of DMPA

A

Failure rate is <1%.

30
Q

Progestin-Only Subcutaneous Implant. Marketed under the trade name of Nexplanon, this uses _______ as the active ingredient

A

etonogestrel

31
Q

Progestin-Only Subcutaneous Implant contains small amount of _____ making
it visible on x-ray.

A

barium,

32
Q

Progestin-Only Subcutaneous Implant

The continuous release continues for ____

A

3 years

33
Q

Progestin-Only Subcutaneous Implant

failure rate

A

Failure rate is <1%.

34
Q

“Morning-After” Pill. Marketed under the trade name of “Plan B,” it uses ______

A

levonorgestrel tablets.

35
Q

“Morning-After” Pill failure rate

A

Failure rate is <1%.

36
Q
Mechanisms of Action of IUD
1
2
3
4
5
A

inhibition of sperm transport;

increased tubal motility causing failure of implantation of immature zygote;

inhibition of implantation secondary to
endometrial inflammation;

phagocytic destruction of sperm and blastocyst;

and alteration of cervical mucus

37
Q

alteration of cervical mucus only for

A

only progesterone IUSs).

38
Q

Absolute Contraindications for IUD include a
1
2
3

A

confirmed or suspected pregnancy;

known or suspected pelvic malignancy;

undiagnosed vaginal bleeding; and

known or suspected salpingitis

39
Q

Relative Contraindications for IUD

A

abnormal uterine size or shape; medical condition (e.g., corticosteroid
therapy, valvular heart disease, or any instance of immune suppression increasing the risk of infection); nulligravidity; abnormal Pap smears; and history of ectopic pregnancy

40
Q

IUD

The LNG-containing IUS is effective for ______years, the copper T-380A is effective for ____ years, making it potentially the
least expensive contraceptive available.

A

5

10

41
Q

This patient’s recent _______ is a significant risk factor for IUS use. Most of the increased risk of infection actually attributable to IUS use is within 20 days after infection

A

chlamydia infection

42
Q

_______ could also be a relative contraindication because they
alter the shape of the endometrial cavity or cause heavy bleeding

A

Uterine fibroids

43
Q

Ectopic pregnancy in IUD

A

The IUS does not increase ectopic pregnancies. However, with
pregnancy from failed IUS, the likelihood of it being ectopic is higher because primarily,
intrauterine pregnancies are prevente

44
Q

A levonorgestrel-impregnated (LNG) IUS that releases the hormone gradually over 5 years.

Bleeding and cramping may be decreased. Failure rate is <1%.

A

“Mirena.”

45
Q

______. A smaller (LNG) IUS similar to Mirena but effective for only 3 years. Failure rate
is <1%.

A

Skyla

46
Q

________ Marketed under the trade name “Paraguard,” this copper-banded
IUS releases copper gradually over 10 years. Bleeding and cramping may be increased

A

Copper T-380A IUS.

47
Q

Disadv of coitus interuptus

A

High failure rates. No protection against STDs. High degree of discipline
required. Semen can enter vagina and cervical mucus prior to ejaculation.

48
Q

plain water, vinegar and other products are used immediately after
orgasm to theoretically flush semen out of the vagina. It has a long history of use in the
United States.

A

With vaginal douche,

49
Q

With lactation, elevated_____ with exclusive breastfeeding inhibit pulsatile secretion
of GnRH from the hypothalamus

A

prolactin levels

50
Q

Effectiveness of LAM

A

Effectiveness is dependent on the frequency (at least every 4-6 hours day & night) and intensity (infant suckling rather than pumping) of milk removal.

51
Q

Disadvantages of LAM:

A

High failure rate if not exclusively breastfeeding. Reliable for only up to
6 months. No protection against STDs.

52
Q

Tubal Ligation

Destruction or removal of a segment of the oviduct is performed in an operating
room through a transabdominal approach usually using a

A

laparoscopy or minilaparotom

53
Q

Failure rate of Tubal Ligation

A

Failure rate is 1 in 200

54
Q

Destruction or removal of a segment of vas deferens is performed as an outpatient
procedure using local anesthesia

A

Vasectomy.

55
Q

Vasectomy failure rate

A

Failure rate is 1 in 500

56
Q

A successful Vasectomy can be

confirmed by

A

absence of sperm on a semen specimen obtained 12 ejaculations after the surgery.

57
Q

Sperm antibodies can be found in _____ of vasectomized patients.

A

50%