Fertility Control Flashcards
These are locally active devices preventing entry of sperm in through the cervix, thus preventing pregnancy.
BARRIER-SPERMICIDAL METHODS
BARRIER-SPERMICIDAL METHODS Advanatges
Barrier methods become increasingly effective with advancing age and the associated natural decline in fertility.
They do protect against some STDs.
They do not have systemic
side effects.
Failure rate of BARRIER-SPERMICIDAL METHODS
approaches 20%.
They are the most common barrier contraceptive method used.
Condoms
This is a dome-shaped device placed in the anterior and posterior vaginal fornices holding spermicidal jelly against the cervix. It can be placed an hour before intercourse.
Vaginal diaphragm
Disadv of Vaginal diaphragm
Individual fitting is required. If too large a size is used, it can result in urinary retention.
The active ingredient is nonoxynol-9, a surface-active agent that disrupts
cell membranes, thus the possible side effect of genital membrane irritation
Spermicides.
These include inhibition of the midcycle luteinizing hormone (LH) surge, thus preventing ovulation;
alteration of cervical mucus making it thick and viscid, thus retarding sperm penetration; and alteration of endometrium inhibiting blastocyst implantation
STEROID CONTRACEPTION
Mechanism of Action of Steroid Contraception
Pituitary _____
Ovary_______
Endometrium_____
Cervix ______
↓ LH surge
↓ ovulation
Atrophy
Hostile mucus
Estrogen effect of steroid hormones
1 2 3 4 5
fluid retention from decreased sodium
excretion;
accelerated development of cholelithiasis;
increase in hepatic protein production
healthy lipid profile changes
and increased venous and arterial thrombosis
What hepatic proteins are increased with estrogenic effects of steroid hormones
(e.g., coagulation factors, carrier proteins, angiotensinogen);
Lipid changes of estrogen
(increase in high-density lipoproteins [HDL]; decrease in low-density lipoproteins [LDL]);
Progestin-Mediated Metabolic Effects of steroid hormones
These include mood changes and depression from decreased serotonin levels; androgenic effects (e.g., weight gain, acne); and unhealthy lipid profile changes (decreased HDL, increased LDL).
Absolute Contraindications of steroid hormones
acute liver disease; history of vascular
disease cerebrovascular accident
[CVA], systemic lupus erythematosus [SLE]); hormonally dependent cancer (e.g., breast);
smoker ≥35; uncontrolled hypertension; migraines with aura; diabetes mellitus with vascular disease; and known thrombophilias
Relative Contraindications of steroid hormones.
These include migraine headaches, depression, diabetes mellitus,
chronic hypertension, and hyperlipidemia
Noncontraceptive Benefits of steroid hormones
These include decreased ovarian and endometrial cancer; decreased dysmenorrhea and dysfunctional uterine bleeding; and decreased PID and ectopic
pregnancy.
Noncontraceptive Benefits of steroid hormones usually from what component
Mostly Progestin Component
These contain both an estrogen and a progestin. They are administered
most commonly in one of two ways: daily with 21 days on and 7 days off or daily 24 days on
and 4 days off
Combination OCPs
COCP
When “off” the hormones, _____will occur
withdrawal bleeding
COCP failure rate
Failure rate is 2% with ideal use.
A unique combination of OCP (YAZ) reduces severe PMDD symptoms by 50%. It contains______ and a new progestin, _____. The dosing is 24 days of active pills then 4 days of placebo, rather than the traditional 21 days
ethynyl estradiol
drospirenone
Marketed under the trade name of NuvaRing, this device, inserted into the vagina, contains both an estrogen and a progestin. It is removed after 3 weeks for 1 week to allow for a withdrawal bleed.
Combination Vaginal Ring