Fertilisation Of The Egg Flashcards
0
Q
What is the factor that “wakes up” the egg?
A
Calcium elevation
1
Q
What stage is the egg arrested in prior to activation?
A
Metaphase 2
2
Q
What are the roles of calcium elevation?
A
- Block polyspermy
2. Meitoic resumption
3
Q
What is the factor in the sperm that activates calcium oscillations in the egg?
A
Phospholipase C zeta
4
Q
How many times bigger is the egg in volume than the sperm?
A
500,000
5
Q
What’s the key indicator that fertilization has occurred?
A
2 pro nuclei
6
Q
What drives the first day of development?
A
Maternal mRNA and proteins already present in the embryo
7
Q
What happens at the 2 cell stage?
A
Zygotic genome activation
8
Q
How is a “good” egg picked in IVF?
A
It’s appearance
9
Q
What are the 2 features to look for when picking a “good” embryo?
A
- symmetry
2. Timing
