Blastocyst And Its Lineages Flashcards

0
Q

What is the outer cell mass called?

A

Trophoblast

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1
Q

What is the first cell fate decision?

A

ICM OR OCM

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2
Q

What cells come from the trophoblast?

A

Trophoblast stem cells

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3
Q

What cells come from the hypoblast?

A

XEN cells

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4
Q

What cells come from the epiblast?

A

Embryonic stem cells

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5
Q

What germ layer gives rise to brain, skin, nails, eyes and hair?

A

Ectoderm

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6
Q

What germ layer gives rise to muscles, bone, heart, vasculature, kidneys?

A

Mesoderm

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7
Q

What germ layer gives rise to the gut, lungs, liver, pancreas and bladder?

A

Endoderm

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8
Q

What are the 2 Cardinal properties of a stem cell?

A
  1. The ability to self renew (immortal)

2. The ability to differentiate into multiple cell types

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9
Q

What cells are important for organizing the early embryo and appear shiny, round and ciliated?

A

XEN cells

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10
Q

What cells have huge nuclei with gaps around them?

A

TS cells

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11
Q

What cells are responsible for giving rise to the entire embryo?

A

Embryonic stem cells

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12
Q

What name is given to the process in which one X chromosome is inactivated?

A

Imprinting

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13
Q

What gene costs chromosomes for inactivation?

A

Xist

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14
Q

In what cell type is the imprinting random?

A

ES cells

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15
Q

In what cell types is the paternal X chromosome ALWAYS inactivated?

A

TS cells and XEN cells