Blastocyst And Its Lineages Flashcards
What is the outer cell mass called?
Trophoblast
What is the first cell fate decision?
ICM OR OCM
What cells come from the trophoblast?
Trophoblast stem cells
What cells come from the hypoblast?
XEN cells
What cells come from the epiblast?
Embryonic stem cells
What germ layer gives rise to brain, skin, nails, eyes and hair?
Ectoderm
What germ layer gives rise to muscles, bone, heart, vasculature, kidneys?
Mesoderm
What germ layer gives rise to the gut, lungs, liver, pancreas and bladder?
Endoderm
What are the 2 Cardinal properties of a stem cell?
- The ability to self renew (immortal)
2. The ability to differentiate into multiple cell types
What cells are important for organizing the early embryo and appear shiny, round and ciliated?
XEN cells
What cells have huge nuclei with gaps around them?
TS cells
What cells are responsible for giving rise to the entire embryo?
Embryonic stem cells
What name is given to the process in which one X chromosome is inactivated?
Imprinting
What gene costs chromosomes for inactivation?
Xist
In what cell type is the imprinting random?
ES cells