Fentanyl Citrate (Sublimaze)

Question 1

Fentanyl
Classification

Answer 1

Narcotic analgesic

Question 2

Fentanyl
Mechanism of Action

Answer 2

Opiate R agonist-hyperpolarization of interneurons and decreased release of neurotransmitters responsible for the transmission of pain impulses to the thalamus and cerebral cortex

Question 3

Fentanyl
Onset of Action

Answer 3

Immediate

Question 4

Fentanyl
Peak Effects

Answer 4

3-5 min IV

Question 5

Fentanyl
Duration of Effect

Answer 5

30-60 min

Question 6

Fentanyl
Half-life

Answer 6

6-8 hrs

Question 7

Fentanyl
Indications/Field Use

Answer 7

Pain management
Adjunct for RSI

Question 8

Fentanyl
Contraindications

Answer 8

Respiratory depression or insufficiency
Incorrected hypotension
Known hypersensitivity

Question 9

Fentanyl
Side Effect

Answer 9

Bradycardia
Respiratory depression
Apnea
Chest wall rigidity

Question 10

Fentanyl
Adult Dose

Answer 10

-1mcg/kg slow IV/IO/IN (max single dose 100mcg)
-Repeat q 5min to max dose 300mcg
->65y/o 0.5mcg/kg slow IV/IO/IN (max single dose 50mcg)

Question 11

Fentanyl
Pedi Dose

Answer 11

-1mcg/kg IV/IO/IM/IN (max single dose 100mcg)
-may repeat 0.5mcg/kg (max dose 50mcg) q 5min to a total of 3 doses

Question 12

Fentanyl
Precautions

Answer 12

Caution in patients with kidney and liver dysfunction

Question 13

Fentanyl
Drug-drug Interactions

Answer 13

-Additive effects w/ CNS depressants
-Should not be given with patients using MAOI in the last 14 days, may cause Serotonin Syndrom