Female reproductive system- Vulva, Vagina, Cervix Flashcards
Viruses causing Vulvitis
1) HPV
2) HSV-1, HSV-2
Fungus causing Vulvitis
Candida Albicans
Bacteria causing Vulvitis
Neisseria Gonorrhoea
Parasit causing Vulvitis
Trichomonas Vaginalis
Complication of Vulvitis
Bartholin Gland Cyst
Cause of Bartholin Gland Cyst
Obstruction of the excretory ducts of Bartholin glands
Clinical presentation of Bartholin Gland Cyst
painful dilation of the glands
(Bartholin Cyst) and abscess formation
Microscopic findings:
– Most common lining: Transitional-type epithelium
– However, cuboid, columnar, ciliated, and squamous
cells may be also observed
– The cyst wall contains a variable number of chronic inflammatory cells and normal or atrophic acini
Macroscopic findings:
- Unilocular cyst filled with serous fluid
features of?
Bartholin Gland Cyst
patho of Lichen Scleroscus
Presence of activated T-cells in the subepithelial inflammatory infiltrate and the increased frequency of autoimmune disorders suggest an
autoimmune aetiology
Epi of Lichen Sclerosus
post-menopausal women
Clinical presentation of Lichen Sclerosus
White plaques (leukoplakia) or
papules
Microscopic findings:
1. Thinning of the epidermis
2. Disappearance of rete pegs
3. Hydropic degeneration of the basal cells
4. Dermal fibrosis
5. Scant perivascular mononuclear inflammatory cell
infiltrate
features of?
Lichen Sclerosus
DD of Lichen Sclerosus
Other causes of leukoplakia, such as Psoriasis, Lichen Planus and Squamous Cell Carcinoma (in situ or invasive)
Progression & Prognosis of Lichen Sclerosus
Benign, but slightly increased (1-5%) risk of SCC
patho of Lichen Simplex Chronicus
autoimmune aetiology
Clinical presentation of Lichen Simplex Chronicus
White plaques (leukoplakia) or
papules
Microscopic findings:
1. Epithelial thickening (particularly of the stratum granulosum)
2. Hyperkeratosis (thickening of the startum corneum, outer layer of skin)
3. Increased mitotic activity in the basal and suprabasal layers
4. No epithelial atypia
5. Leukocytic infiltration of the dermis
features of ?
Lichen Simplex Chronicus
DD of Lichen Simplex Chronicus:
Other causes of leukoplakia, such as Psoriasis, Lichen Planus and Squamous Cell Carcinoma (in situ or invasive)
progression & prognosis of Lichen Simplex Chronicus
Benign, isolated lesions, that do not have a risk of developing SCC
Which has a risk of developing SCC, Lichen Simplex Chronicus/ Lichen Sclerosus
Lichen sclerosus