Female Reproductive System and Breast Flashcards

1
Q

Lab confirmation of premature ovarian failure.

A

less than 40years with amenorhea for >3mo and elevated FSH levels

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2
Q

describe HELLP

A

severe HTN + proteinuria + labs

systemic inflammation and activation of coag systme and complement cascade. platelets consumed and MAHA –> hepatocellular necrosis

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3
Q

Acute abdominal/pelvic pain in women:
recurrent mild and unilateral mid-cycle pain prior to ovulation. pain lasts hours to days.

dx and U/s findings

A

mittelschmertz

no u/s findings

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4
Q

Acute abdominal/pelvic pain in women:
amenorrhea, abd/pelvic pain and vaginal bleeding. psotive beta-hCG

dx and U/s findings

A

ectopic pregnancy

no intrauterine pregnancy seen

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5
Q

Acute abdominal/pelvic pain in women:
sudden onset, severe, u/l lower abd pain; N/V.
u/l tender adnexal mass on exam

dx and U/s findings

A

ovarian torsion

enlarged ovary with decreased or absent blood flow

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6
Q

Acute abdominal/pelvic pain in women:
sudden onset, severe, u/l lower abd pain immediately following strenuous or sexual activity

dx and U/s findings

A

ruptured ovarian cyst

pelvic free fluid

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7
Q

Acute abdominal/pelvic pain in women:
fever, chills, vaginal discharge, lower abd pain and cervical motion tenderness

dx and U/s findings

A

PID

+/- tubo-ovarian abscess

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8
Q

HPI: intense pruritis, dyspareunia, pain with defecation
PE: pale thin tissue and perianal thickening with fissures, spares vagina

A

lichen sclerosus - vulvar premalignant lesion

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9
Q

possible lichen sclerosus dx - then what?

A

vulvar punch bx for definitive dx of vulvar SqCCa

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10
Q

HPI: vulvovaginal dryness
PE: decreased vaginal diameter, loss of vaginal elasticity/rugae, thinning vulvar skin/loss of minora

A

atrophic vaginitis

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11
Q

tx of lichen sclorosis v. atrophic vaginitis

A

lichen - high potency topical steroids

atrophic - low dose topical estrogen

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12
Q

Acute: SOB, obstipation/constipation with vomiting, abd distension
Subacute: pelvic/abd pain, loating, early satiety

A

epithelial ovarian Carcinoma

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13
Q

Tx of chlamydia +/- gonorrhea

Tx for PID

A

Empiric: azithro + ceftriaxone
Confirmed chlamydia: azithro
Confirmed gonorrhea: azithro + ceftriaxone

PID: ceftriaxone and doxycycline

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14
Q

four non-modifiable risk factors for breast cancer

A
  1. age
  2. genetics or first degree relative with breast cancer
  3. white race
  4. early menarche or later menopause
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15
Q

soft, mobile nontender cystic mass usually asx , found at 4 or 8 o’clock position at base of labium majora

dx
tx

A

bartholin duct cyst

tx: asx - no intervention
sx - i/d

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16
Q

name two competitive inhibitors of E binding.
Indications for each
AE for both

A

Tamoxifen - breast cancer treatment
Raloxifene - postmenopausal osteoporosis
AE - hot flashes, venous thormboembolism, endometrial hyperplasia and carcinoma (tamoxifen)

17
Q

complications of PID (four)

A

tuboovarian abscess
perihepatitis
ectopic pregnancy
infertility

18
Q

Absolute CI to combined hormonal contraceptives

A
Migraine WITH aura
BP >160/100
>15 cigs/day and >35y
Hx of VTE
Hx of stroke or ischemic heart disease
Breast cancer
Cirrhosis, liver cancer
maojor surgery with prolonged immobilization
<3wks postpartum
19
Q

best emergency contraception option for 0-120 hours

A

copper IUD

20
Q

Definition of infertility on <35 v >/=35

A

<35 is 12mo

>/=35 is 6mo

21
Q

U/S findings of hyperechoic nodules and calcifications in a premenopausal women with adnexal fullness on PE and otherwise asx.

A
dermoid cyst (mature cystic teratoma)
B9 germ cell tumor.
22
Q

modifiable breast cancer risk factors (4)

A

alcohol
HRT
nulliparity
increased age at first brith

23
Q

FSH in menopause

24
Q

T and E levels in PCOS

25
SOB, obstipation/constipation, vomiting, abd distention. askx adnexal mass
CA-125 incr Epithelial ovarian Ca
26
Multiparous >40y, dysmenorrhea, heavy menstrual bleeding. progression to chronic pelvic pain. PE: boggy, tender, uniformly enlarged uterus
adenomyosis
27
tx of endometriosis
NSAIDs +/- OCPs or Laparoscopy
28
At what age is optimal fertility?
18y
29
normal internal genetalia, ambiguous external/virilizaiton (clitoromegaly), undetectable serum estrogen levels Dx
congenital aromatase deficiency
30
HPI: postmenopausal bleeding Imaging: U/S = thickened endometrium Dx and path:
Dx: granulosa cell tumor of the ovary path: estrogen secreting = endometrial hyperplasia or carcinoma, which causes postmeno bleeding
31
tx for pts who desire lactation suppression
ice packs and ANALGESICs
32
PCOS who wants to have children.
weight loss first, then if unsuccessful --> clomiphene citrate to induce ovulation