Female Reproductive Cycle- Lecture 6 Flashcards
Luteolysis
The CL regressing if their is no pregnancy. Progesterone falls. PGF2alpha is released from edometrium and causes CL destruction.
Anestrus
Anytime a female is not cycling. Can be due to: seasons, pregnancy, lactation, stress, or pathology.
Short-day breeders
Sheep and goats. Cyclicity occurs during fall months. Decreased daylight causes increased melatonin. Melatonin stimulates secretion of GnRH in short-day breeders.
PGF2alpha
Prostaglandin F2 alpha. Produced by endometrium. Destroys CL (luteolysis)
Estrous cycle
Reproductive cycle of non-primate species. Period from one estrus cycle to the next. Has a follicular phase and luteal phase.
FSH
Produced and released from anterior pituitary. Promotes follicular development in females. Stimulated by GnRH and inhibited by inhibin.
Metestrus
Period of transition from estrus to diestrus. Time when CL is forming. Estrogen begins to fall and progesterone rises. Female is no longer receptive.
LH
Produced and released from anterior pituitary. Causes follicular maturation and ovulation. Promotes development and maintenance of corpus luteum. Stimulated by GnRH and inhibited by progesterone.
Estrogen
Produced by ovarian follicles. Causes estrous behavior and inhibits FSH. Once it reaches high enough levels it causes a surge in GnRH.
Monoestrus
One estrus cycle a year. Wolves, foxes, bears, and dogs. Has an anestrus phase.
Estrus
Period of behavioral receptivity during the estrous cycle. “Heat” or season. Estrogen from dominant follicle is high. Progesterone is low. Ovulation occurs.
Polystrous
Repeated estrous cycles are uniformly distributed throughout the year. Cattle, swine, rodents.
Progesterone (P4)
Produced by CL. It is essential for pregnancy maintenance. Inhibits estrous behavior and GnRH secretion.
Diestrus
High progesterone. Uterus preparing for possible pregnancy. Female with refuse male. Follicles can develop but doesn’t ovulate.
Seasonally polyestrous
Repeated estrous cycles for a portion of the year. Horses, sheep, goats, cats.
GnRH
Synthesized and released from hypothalamus. Stimulates production and secretion of LH and FSH by the anterior pituitary.
Long-day breeders
Horses. Cyclicity occurs in spring&summer months. Increased daylight causes decreased melatonin. Melatonin secretion inhibits GnRH in long-day breeders.
Hypothalamic-pituitary-gonadal Axis
Hypothalamus (GnRH) –> Anterior Pituitary (LH and FSH) –> Ovary (inhibin, estrogen, progesterone)
Proestrous
Begins when progesterone declines following luteolysis. Follicles are recruited and estrogen increases as they develop. Repro tract prepares for estrus & mating. Female doesn’t allow mating yet.
Seasonal cyclicity
Seasonally polyestrous animals cycle only during a portion of the year. Give birth during environmental conditions that are favorable for neonatal survival. GnRH secretion is regulated by photoperiod and temperature. More darkness= more melatonin produced by pineal gland.
Phases of estrous cycle
Follicular phase: where ovulation occurs, estrogen peaks. 20 % of cycle. Subdivided into proestrous and estrus. Luteal phase: 80% of cycle. Estrogen levels low, dominated by progesterone. Subdivided into metestrus and diestrus.