female repro part I Flashcards

1
Q

what part of the ovary contains the developing follicles?

A

cortex

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2
Q

where is the cortex located in the mare?

A

centrally

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3
Q

what is the edge of the cortex in the center of the ovary in the mare?

A

ovulation fossa

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4
Q

what is the tissue between the follicles referred to as?

A

stroma

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5
Q

what are the characteristics of the stromal cells

A
  1. fibroblast-like

2. with lipid droplets

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6
Q

what is the CT around the outer edge of the cortex

A

tunica albuginea

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7
Q

what is the covering over the ovary?

A

tunica serosa ( AKA mesovarium)

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8
Q

what kind of epithelium does the tunica serosa have?

A

simplie cuboidal (that gets more squamous with age)

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9
Q

what contains the blood vessels of the ovary?

A

ovarian medulla

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10
Q

what are the system of channels in the ovary that can for cysts and tumors?

A

rete ovarii

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11
Q

what are the stem cells that divide mitoically until birth, that give rise to primary oocytes (which become arrested in meiotic prophase I)

A

oogonia

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12
Q

when stimulated to divide, what type of division do primary oocytes complete/become?

A
  1. meiosis I

2. form secondary oocyte and the 1st polar body

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13
Q

when is the secondary oocyte formed in most species?

A

just prior to ovulation

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14
Q

what type of oocye do the mare and dog ovulate?

A

primary oocyte

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15
Q

regardless of stage of development of the follicle, all obserable follicles on slides of postnatal ovaries contain what kind of oocyte?

A

primary oocyte

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16
Q

when does the secondary ooctye undergo the 2nd meiotic division?

A

right after fertilization

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17
Q

what is formed by the secondary oocyte after meiosis II?

A
  1. ovum

2. 2nd polar body

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18
Q

female germ cells in most animals are arrested at what stage of development until the time of ovulation??

A

primary oocyte

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19
Q

what surrounds the oocyte inside the follicle, that is a capsule-like structure

A

zona pellucida

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20
Q

what is the layer of epithelial cells around the oocyte?

A

granulosa cells

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21
Q

what is the zona pellucida made of ?

A

a think glycoprotein layer

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22
Q

what secretes the zona pellucida?

A

both the oocyte and granulosa cells

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23
Q

what surrounds the follicular epithelial cells (granulosa cells)

A
  1. basement membrane

2. theca (interna/externa)

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24
Q

what are the stages of the follicle?

A
  1. primodial
  2. primary
  3. secondary
    4 tertiary (Graafian)
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25
what follicle has the oocyte surrounded by a single layer of squamous cells
primordial follicles
26
what type of follicle has the oocyte surrounded by cuboidal granulosa cells?
primary follicle
27
what type of follicle do small pockets of follicular fluid appear between granulosa cells?
secondary follicle
28
what type of follicle has one large fluid-filled cavity (antrum) with a layer of granulosa cells around the periphery (stratum granulosum)
tertiary follicle
29
in advanced follicles, the granulosa cells are divided into what specific areas? (most interior to exterior)
1. corona radiata 2. cumulus oophorus (surrounds oocyte) 3. stratum granulosum
30
what are the follicles that are degenerating?
atretic follicles
31
can a follicle become atretic at any stage?
yes
32
what cells are often ovulated with the oocyte?
cumulus oophorus
33
what cells are formed in the dog and cat from theca interna cells, which persist?
interstitial cells
34
what are the two general phases of the ovarian cycle?
follicular and luteal
35
what is the transient endocrine gland derived from an ovulated follicle?
corpus luteum
36
what does the CL produce?
progesterone
37
what hormone plays a large role in the establishment and maintenance of pregnancy?
progesterone
38
CL regression is an example of:
apoptosis
39
what hormone is involved in the regression of the CL?
PGF2alpha
40
what stage is the CL degenerating/regressing?
follicular stage
41
what stage is the follicle maturing toward ovulation?
follicular stage
42
what stage is estrogen being produced by the granulosa cells in response to FSH?
follicular stage
43
late in what stage does the LH surge trigger ovulation?
follicular stage
44
what stage is the endometrium in the uterus proliferating?
follicular stage
45
theca cells have what kind of receptors?
LH receptors
46
what do theca cells produce?
androgens
47
what type of receptors do granulosa cells have initially?
FSH receptors
48
what do granulosa cells produce?
estrogens
49
estrogen has what kind of feedback on granulosa cells?
positive
50
granulosa cells later develop what kind of receptors?
LH receptors
51
rising estrogen levels during the follicular phase stimulates what?
release of LH from pituitary (causes LH surge)
52
what does the LH surge stimulate?
1. primary oocyte to complete meiosis I 2. starts process of ovulation 3. induces formation of CL
53
what cells form the CL?
granulosa and theca cells
54
in what phase is P4 produces by the CL
luteal phase
55
in what phase are there several waves of follicles that become atretic?
luteal phase
56
in what phase are the uterine glands secreting?
luteal phase
57
LH secretion maintains what?
CL
58
P4 stimulates development of what?
uterine endometrium
59
P4 from the CL inhibit what?
FSH and LH release
60
what CL degenerates each cycle that there is no implantation?
CL cyclicum
61
what CL persists if there is implantation?
CL of pregnancy
62
what is the CL gradually replace by that is a CT scar?
corpus albicans
63
P4 has what type of feedback on LH secretion?
negative