Female Repro

Question 1

What is dicloxacillin used for?

Answer 1

acute mastitis tx (staph. aureus)

Question 2

What is the tx for acute mastitis?

Answer 2

dicloxacillin and continued breastfeeding

Question 3

What is tamoxifen used for?

Answer 3

breast CA (E agonist)

Question 4

What is the tx for Lobular Carcinoma in Situ (LCIS)?

Answer 4

tamoxifen and watchful waiting

Question 5

What is trastuzumab used for?

Answer 5

Her2/neu breast CA

Question 6

What is the tx for Her2/neu (+) breast CA?

Answer 6

trastuzumab

Question 7

What is leuprolide used for?

Answer 7

GnRH analog = agonist when pulsatile, antagonish when continuous

“LEUprolide can be used in LEU of GnRH”

Question 8

What is the tx for uterine fibroids?

Answer 8

leuprolide

Question 9

What is are ethinyl estradiol/DES/mestranol used for?

Answer 9

hypogonadism/ovarian failure
menstrual ab.
HRT
androgen-dependent prostate CA

Question 10

What is the tx for female infertility?

Answer 10

leuprolide (pulsatile)

Question 11

What is Clomiphene used for?

Answer 11

infertility due to anovulation (PCOS)

Question 12

What is the tx for precocious puberty?

Answer 12

leuprolide (continuous)

Question 13

What is the tx for infertility due to anovulation (PCOS)?

Answer 13

Clomiphene (a SERM)

Question 14

What are the SEs for leuprolide?

Answer 14

antiandrogen, n/v

Question 15

What is the tx for hypogonadism/ovarian failure?

Answer 15

ethinyl estradiol/DES/mestranol

Question 16

What is the tx for menstrual abnormalities?

Answer 16

ethinyl estradiol/DES/mestranol

progestins

Question 17

What is the tx for menopause symptoms?

Answer 17

ethinyl estradiol/DES/mestranol

Question 18

What is Raloxifene used for?

Answer 18

osteoporosis

Question 19

What is the tx for osteoporosis?

Answer 19

Raloxifene

Question 20

What is anastrozole used for?

Answer 20

postmenopausal breast CA

Question 21

What is exemestane used for?

Answer 21

postmenopausal breast CA

Question 22

Name 2 drugs for postmenopausal breast CA.

Answer 22

anastrozole

exemestane

Question 23

What are progestins used for?

Answer 23

oral contraception
endometrial CA
abnormal uterine bleeding

Question 24

Name a tx for endometrial CA.

Answer 24

progestins

Question 25

What is RU-486?

Answer 25

mifepristone

Question 26

What is mifepristone used for?

Answer 26

abortions (with misoprostal)

Question 27

What medication induces abortion?

Answer 27

mifepristone (with misoprostal)

Question 28

What are the contraindications for oral contraceptives?

Answer 28

smokers > 35yo pts with hx of thromboembolism/stroke hx of E-dependent tumor

Question 29

What is terbutaline used for?

Answer 29

to decrease uterine contraction frequency in labor

Question 30

This drug is used to decrease uterine contraction frequency in labor.

Answer 30

terbutaline

Question 31

At what receptor does terbutaline work?

Answer 31

beta-2 (agonist)

Question 32

What is danazol used for?

Answer 32

endometriosis | hereditary angioedema

Question 33

What is a tx for both endometriosis and hereditary angioedema?

Answer 33

danazol

Question 34

What are the SEs for danazol?

Answer 34

weight gain, edema, acne, hirsutism, masculinization, decreased HDL, hepatotox

Question 35

What is used in PCOS to prevent hirsutism?

Answer 35

ketoconazole | spironolactone