Female Repro Flashcards
What is dicloxacillin used for?
acute mastitis tx (staph. aureus)
What is the tx for acute mastitis?
dicloxacillin and continued breastfeeding
What is tamoxifen used for?
breast CA (E agonist)
What is the tx for Lobular Carcinoma in Situ (LCIS)?
tamoxifen and watchful waiting
What is trastuzumab used for?
Her2/neu breast CA
What is the tx for Her2/neu (+) breast CA?
trastuzumab
What is leuprolide used for?
GnRH analog = agonist when pulsatile, antagonish when continuous
“LEUprolide can be used in LEU of GnRH”
What is the tx for uterine fibroids?
leuprolide
What is are ethinyl estradiol/DES/mestranol used for?
hypogonadism/ovarian failure
menstrual ab.
HRT
androgen-dependent prostate CA
What is the tx for female infertility?
leuprolide (pulsatile)
What is Clomiphene used for?
infertility due to anovulation (PCOS)
What is the tx for precocious puberty?
leuprolide (continuous)
What is the tx for infertility due to anovulation (PCOS)?
Clomiphene (a SERM)
What are the SEs for leuprolide?
antiandrogen, n/v
What is the tx for hypogonadism/ovarian failure?
ethinyl estradiol/DES/mestranol
What is the tx for menstrual abnormalities?
ethinyl estradiol/DES/mestranol
progestins
What is the tx for menopause symptoms?
ethinyl estradiol/DES/mestranol
What is Raloxifene used for?
osteoporosis
What is the tx for osteoporosis?
Raloxifene
What is anastrozole used for?
postmenopausal breast CA
What is exemestane used for?
postmenopausal breast CA
Name 2 drugs for postmenopausal breast CA.
anastrozole
exemestane
What are progestins used for?
oral contraception
endometrial CA
abnormal uterine bleeding
Name a tx for endometrial CA.
progestins
What is RU-486?
mifepristone
What is mifepristone used for?
abortions (with misoprostal)
What medication induces abortion?
mifepristone (with misoprostal)
What are the contraindications for oral contraceptives?
smokers > 35yo
pts with hx of thromboembolism/stroke
hx of E-dependent tumor
What is terbutaline used for?
to decrease uterine contraction frequency in labor
This drug is used to decrease uterine contraction frequency in labor.
terbutaline
At what receptor does terbutaline work?
beta-2 (agonist)
What is danazol used for?
endometriosis
hereditary angioedema
What is a tx for both endometriosis and hereditary angioedema?
danazol
What are the SEs for danazol?
weight gain, edema, acne, hirsutism, masculinization, decreased HDL, hepatotox
What is used in PCOS to prevent hirsutism?
ketoconazole
spironolactone