Female 2: Ovarian cycle

Question 1

define ovularian cycle

Answer 1

period of time between 2 successive ovulations

Question 2

Describe follicular phase

Answer 2

it begins on day 1 of the cycle, corresponding to first day of menses:
* it occurs under the effect of increased levels of FSH more than LH
* At the beginning, granulosa cells have receptor for FSH only, and theca cells for LH
* At the end, accumulation of FSH induced cAMP in Granulosa cells —> have LH receptor as well
* LH then acts as surogate for FSH

Question 3

Effects of FSH in ovulation

Answer 3

• Proliferation of granulosa cells
• Increase estrogen production from granulosa cells
• formation of follicular fliud
• Formation of theca cells, differentiate into —> glandular theca interna & fibrous theca externa
• Formation of Zona pellucida
• Increase gap junction between cells for transportation of nutreints