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Surgical Oncology > Feline Specific Oncology > Flashcards

Feline Specific Oncology Flashcards

1
Q

Other than injections, what have been described to have caused Injection site sarcomas?

A

Non absorbable material

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2
Q

What type of biopsy is recommended for diagnosis of suspected ISS?

A

Incisional

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3
Q

Why are excisional biopsies contraindicated with ISS? (2)

A

Tumour recur
Decreased dx free interval

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4
Q

Why are FNA and trucut biopsies not advised for ISS? (1)

A

Extensive inflamm - misdiagnose as granuloma

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5
Q

What is the “321” rule with inject site sarcomas?

A

If the mass has been present for longer than 3 months.

If the mass is wider than 2 cm in diameter.

If the mass increases in size after 1 month.

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6
Q

What is the most important treatment component for ISS?

A

Surgery

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7
Q

What margins should be taken for ISS?

A

Aggressive, radical surgery is recommended. In practice, this means surgery with at least 3 cm (preferably 5 cm) margins peripherally and one (preferably two) fascial planes deep to the tumour.
month.

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8
Q

What should you do if ISS includes an adjacent bone?

A

part of these bone structures must be removed during surgery

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9
Q

Why is advanced imaging recommended prior to Sx and removal of ISS?

A

Because these tumours are poorly encapsulated and extend along and infiltrate fascial planes,

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10
Q

According to a roundtable convened by VAFSTF (Vaccine Associated feline sarcoma task force, 2005), what is the recommended treatment approach to ISS?

A

Wide surgical excision
Radiotherapy
Chemotherapy

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11
Q

Surgery alone with ISS - what is the recurrence rate?

A

70%

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12
Q

Radiation - Long term damage: (4)

A

Vascular damage
Neural damage
Fibrosis
Atrophy
Endocrine/growth effects

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13
Q

Radiation - Short term damage: (2)

A

GI disorders
Derm changes

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14
Q

What is the effectiveness of chemo in ISS?

A

Debatable

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15
Q

ISS:
A markedly longer remission time has been recorded in patients that were additionally treated with a)

A

Doxorubicin

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16
Q

Chemo drug of choice for ISS?

A

Doxorubicin

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17
Q

Side effects of doxorubicin in cats? (3)

A

Anaemia
Myelosupression
Nephrotoxicity

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18
Q

True or false:
A study showed a definite prolonged remission time in patients treated with doxorubicin.

A

True

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19
Q

True or false:
Administration of doxorubicin did prolong the disease-free survival time.

A

False

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20
Q

How many cancers in cats are mammary?

A

20%

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21
Q

What is the most common mammary tumour in cats?

A

Adenocarcinoma

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22
Q

Which breed is higher risk of mammary tumour?

A

Siamese

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23
Q

What is the increased risk of an entire having mammary tumour vs neutered?

A

7 x

24
Q

In order for ovariohysterectomy to have a protective role against mammary tumours, it must be performed early in life. The protective effects diminish quickly and there appears to be no benefit to this after what age in cats?

A

2 years

25
Q

What are the 3 areas to allow adequate staging of mammary tumours?

A
  1. Evaluating the size of the primary tumour
  2. Evaluating the involvement of the regional LN (axillary and inguinal)
  3. Identifying any distant mets (via 3 view thoracic radiographs or thoracic CT and abdominal ultrasound/CT)
26
Q

Mammary tumours - which chemo drug?

A

Doxorubicin +/- others

27
Q

Why is chemotherapy routinely needed in mammary tumours?

A

Neoplastic cells invade lymphatic system

28
Q

What does the survival time with mammary tumours depend on? (4)

A

Size of the tumour
Extent of surgery
The grade
Whether additional therapy is used

29
Q

What two target therapy drugs are used in veterinary?

A

Toceranib (palladia)
Matinib (Masivet)

30
Q

What type of MCT can show systemic signs? (2)

A

Visceral
Disseminated

31
Q

Surgery for disseminated MCT is not recommended - unless…

A

The spleen is involved

32
Q

Which drugs can reduce clinical signs of inflammation or stomach ulceration with MCT?

A

histamine receptors antagonist (such as cyproheptadine and famotidine)

33
Q

What drug can be used to reduce inflammation with MCT?

A

Steroids

34
Q

What is a major cause of SCC in cats?

A

sunlight

35
Q

Where to SCC most commonly form in cats?

A

Ears, eye ridges, eyelids, nose, or lips of cats that have white skin in these regions.

36
Q

What is the most common oral tumour in cats?

A

SCC

37
Q

Which of the following have been associated with a significantly increased risk of developing oral SCC?
A) Diet consisting of dry commercial food only

B) Exposure to household tobacco smoke

C) Exposure to plug in room fresheners

D) High intake of canned food (especially canned tuna fish)

E) The use of flea collars

A

B) Exposure to household tobacco smoke
D) High intake of canned food (especially canned tuna fish)

E) The use of flea collar

38
Q

SCC in cats - met rate?

A

low

39
Q

What tumour accounts for 15-26 % of all skin tumours in cats.

A

Basal cell

40
Q

Which breeds have a breed predisposition for basal cell tumour? (3)

A

DLH
himalayan
persian

41
Q

What colour do basal cell tumours TEND to be?

A

dark

42
Q

Haemangiosarcomas of the skin tend to effect which cats?

A

White/those than sunbathe

43
Q

Where do haemangiosarcomas spread? (2)

A

Lungs and liver

44
Q

A) skin lymphosarcoma is the most frequently recognised form of lymphoid skin tumours in cats. The disease tends to develop in older animals. Signs are often extremely subtle: tumours often appear initially as a crusty plaque that may B)

A

A) epitheliotropic
B) itch

45
Q

A) skin lymphosarcoma may occur as either single or multiple tumours that are most likely to develop on the B) of cats.

A

A) Non Epitheliotropic
B) Trunk

46
Q

How common are melanomas?

A

uncommon

47
Q

Where do melanocytic tumours more commonly devevlop?

A

head, digits, ear, and nose

48
Q

What is sebaceous gland hyperplasia?

A

a benign overgrowth of sebaceous gland cells.

49
Q

Which breed is predisposed to Sebaceous gland adenomas?

A

Persian

50
Q

What are the two types of sweat glands?

A

Apocrine
Eccrine

51
Q

Which breed is pre disposed to apocrine gland adenocarcinoma?

A

Siamese

52
Q

Where are eccrine glands found?

A

Footpads

53
Q

Neoplasia Cats with white coats/lighter pigmentation:
Predisposed to… (2)

A

Haemangiosarcoma
SCC

54
Q

Neoplasia Siamese are predisposed to.. (2)

A

Mammary gland tumours
Apocrine gland adenocarcinoma

55
Q

Neoplasia Persians are predisposed to.. (2)

A

Sebaceous gland adenoma
Basal cell tumour

Surgical Oncology (10 decks)

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