Feline Infectious Diseases

Question 1

What kind of virus is Feline Panleukopenia Virus

Answer 1

Parvovirus- Very infectious
Feline Infectious Enteritis

Question 2

FPV: Clinical Syndromes for foetus

Answer 2

Foetus (< 21d)- Abortion
Foetus (>21d)- Cerebellar hypoplasia

Question 3

FPV: Clinical Syndromes for young and older kittens/cats

Answer 3

Young kittens- Sudden death
Older kittens / cats- Intestinal disease (FIE), Severe panleukopaenia

Question 4

Feline Infectious Enteritis C/S

Answer 4

Fever
Inappetence
Anorexia
Vomiting
Severe watery diarrhoea in later stages
Secondary bacterial infection important in determining severity of disease

Question 5

Mortality rate of FPV

Answer 5

25-75%

Question 6

FIE/FPV- Dx

Answer 6

Viral isolation - Faeces, oropharyngeal swab, PCR, canine parvo detection kits

Serology- Acute and convalescent

Question 7

FIE/FPV- Treatment

Answer 7

ISOLATION
Nursing- Warmth, rest, cleanliness, palatable food
IV fluids
Anti-emetics
SC maropitant, IV metoclopramide
IV antibiotics
Interferon ?

Question 8

FIE/FPV Control

Answer 8

Vaccinations effective

Question 9

2 most common cat flu

Answer 9

Feline calicivirus
Feline herpesvirus

Question 10

Feline Herpesvirus (FHV) C/S

Answer 10

URT disease + ocular signs

Question 11

Does Feline Herpes Virus have a latent stage?

Answer 11

Yes. Latent state important

Question 12

Treatment of herpetic ulcers

Answer 12

Topical Interferons
Anti-virals - Aciclovir (5 x daily), Famciclovir
Lysine
Lubrication
Secondary infections

Question 13

Feline Calicivirus- C/S

Answer 13

URT disease Oral ulceration
Viral arthritis
Gingivitis/stomatitis

Question 14

FHV / FCV Diagnosis

Answer 14

Clinical signs are not reliable for DDx
Specific diagnosis important for control, but not for treatment
Oropharyngeal swabs
FHV only after reactivation

Question 15

Chlamydophila felis- C/S

Answer 15

Highly specialised bacterium
Asymptomatic carriers common
Conjunctivitis
+/- mild rhinitis

Question 16

Chlamydophila felis- Tx

Answer 16

tetracyclines for at least 2 weeks after signs have resolved
parenterally in severe cases

Question 17

Is chlamydophilia felis zoonotic

Answer 17

No

Question 18

Feline Infectious Peritonitis FIP is caused by?

Answer 18

Feline Coronavirus

Question 19

Feline Infectious Peritonitis FIP- C/S

Answer 19

Most infections are benign
mild diarrhoea 2-3 days
predominantly in kittens

Question 20

When do cats normally get infected by FCOV

Answer 20

Cats normally infected when kittens by other cats
particularly kittens from other litters
also non-parental adults

Question 21

Describe the two types of FIP

Answer 21

Wet (effusive) FIP
Dry (non-effusive) FIP

Question 22

FIP: Diagnosis

Answer 22

The only definitive way to diagnose FIP is by immunohistopathological examination of a biopsy specimen

Question 23

Wet FIP- C/S

Answer 23

Effusive lesions
Peritoneal - ascites
Pleural - dyspnoea

Question 24

Dry FIP- C/S

Answer 24

Granulomatous lesions
Neurological signs- Ataxia, paresis, nystagmus etc.
Liver and kidney dysfunction
jaundice, PU/PD
Ocular lesions

Question 25

General age of which cat with FIP shows clinical sign

Answer 25

<2 y.o., occasionally >11 y.o.

Question 26

FIP: Clinical Pathology (Blood test results) (4)

Answer 26

Hyperglobulinaemia
Lymphopaenia
Neutrophilia
Anaemia

Question 27

FIP: Treatment

Answer 27

Prognosis WAS hopeless
some cases improve for a while
a few very rare cases have recovered

Now
Nucleoside analogues
Remdesivir

Question 28

Drug given to cats with FIP

Answer 28

Nucleoside analogues
Remdesivir

Question 29

FIP: Control

Answer 29

Vaccination can make disease worse
Either eliminate all coronaviruses by serology Or separate infected cats and tolerate occasional outbreaks

One available vaccine in USA
Intranasal but not widely reccomended