Feline Chlamydophilosis, Mycoplasmosis Flashcards
What bacterium causes feline chlamydophila disease?
Chlamydophila felis
Which clinical signs are commonly observed in cats infected with C. felis?
a) Diarrhea and vomiting
b) Fever, ocular discharge, and sneezing
c) Skin lesions and alopecia
d) Cardiac arrhythmias
Fever, ocular discharge, and sneezing
What is the predominant feature of C. felis infection in cats?
Conjunctivitis
How does the dose of C. felis affect the severity of clinical signs?
Low doses produce unilateral signs, and higher doses produce bilateral illness.
Which tissues can C. felis colonize in infected cats?
Tonsil, lung, liver, spleen, and kidney
How long can C. felis be isolated from the conjunctiva after experimental infection?
up to 215 days
What form of C. felis has been identified in the joints of people with reactive arthritis?
Atypical reticulate bodies
When does shedding of C. felis from the reproductive tract typically occur in kittens?
At 4 to 6 months or older
What factor may influence the replication of C. felis in the reproductive tract?
Hormonal influences
Which site is considered a potential site of persistent C. felis infection in cats?
Intestinal tract
What is the typical involvement of the cornea in C. felis infection?
Corneal disease is rare
What is the relationship between rhinitis and ocular involvement in C. felis infection?
Rhinitis without ocular involvement is unlikely caused by C. felis
What is a common systemic sign observed in experimental C. felis infection?
Fever, lethargy, lameness, and weight loss
What human condition is the lameness observed in experimental feline C. felis infection similar to?
Reiter’s syndrome
What tissue was C. felis isolated from in young cats with weight loss in research colonies?
Gastric mucosa
What reproductive signs occur following experimental conjunctival inoculation?
a) Infertility
b) Vaginal discharge
c) Uterine rupture
d) Pyometra
Vaginal discharge
What signs were observed following intravaginal and intraurethral inoculation of C. felis?
Vaginal discharge, urethritis, and proctitis
What was observed following direct instillation of C. felis into the fallopian tubes?
Two months of shedding and suspected infertility
What is a key difference between natural and experimental C. felis infection?
Experimental infection often shows systemic signs not commonly reported in natural infections.
What is considered the most definitive diagnostic test for feline chlamydophila disease?
culture of the organism
Which type of swab is recommended for collecting samples for C. felis culture?
Cotton swabs
What transport medium is recommended for C. felis samples?
2SP (0.2 M sucrose and 0.02 M phosphate)
What is considered a highly sensitive test for detecting C. felis?
PCR
How long after antibiotic treatment can C. felis PCR results be expected to be negative?
2-3 days
