Feeding and eating disorders Flashcards
What are the risk factors for Anorexia Nervosa?
Perfectionism and poor self-esteem
Early menarche
Exposure to environment in which weight concerns and restrictive dieting prevails
Family history of members who are thin or underweight
What is a general description of What are the risk factors for Anorexia Nervosa?
Intense preoccupation with weight and body shape and a relentless pursuit of thinness.
What are the three key clinical features of What are the risk factors for Anorexia Nervosa?
Underweight for height and age
Intense fear of fatness and gaining weight, or behaviours to avoid weight gain
Overvalued ideas of body weight and shape on self-view, or denial of seriousness of low weight
What are common behavioural characteristics of people with What are the risk factors for Anorexia Nervosa?
Vomiting and laxative abuse Excessive exercise (sometimes covert) Both carried out obsessively with guilt present when not done.
What are the physical and biochemical findings associated with What are the risk factors for Anorexia Nervosa?
Decresed gonadotropins & sex hormones
Altered thyroid metabolism
Raised cortisol and GH
Severe electrolyte disturbances (Potassium, calcium, phosphates)
Cardiac arrhythmias
Renal failure
Osteopenia / osteoporosis
Rectal prolapse
In the emergency treatment of What are the risk factors for Anorexia Nervosa what are the 12 categories of changes that must be monitored and treated?
DR, I GET salty CHIPS, DER
Dental changes
Renal changes
Intercellular changes
Gastrointestinal changes
Endocrine changes
Temperature changes
Electrolyte changes
Cardiac changes Haematological changes Immune system changes Pregnancy changes Skin / bone changes
What is the main intercellular change in Anorexia nervosa and how is it monitored and managed acutely?
Change:
Increased protein catabolism
Monitoring:
Measure pulse and BP lying and standing
What are the main Endocrine changes in Anorexia nervosa and how are they monitored and managed acutely?
Changes:
Dehydration
Oedema
Low gonadotropin and sex steroids (amenorrhea)
Altered peripheral metabolism of thyroid hormone
Raise cortisol and GH
Hyperaldosteronism
Hypoglycaemia
Poor metabolic control in T1DM (needs specialist referral)
Monitoring:
TFT
Monitor hormone imbalances
Repeated BSL monitoring
Acute management:
Thiamine administration with refeeding for hypoglycaemia
What are the main Electrolyte changes in Anorexia nervosa and how are they monitored and managed acutely?
Changes: Hypokalaemia Hypochloraemia Metabolic alkalosis Hypomagnesaemia (**refractory hypokalaemia) Hypoglycaemia Hypophosphatemia Hyperphosphataemia (vomiting)
Monitoring:
Electrolytes
Blood gas
ECG
Acute management:
Careful K+ replacement (oral)
Correct alkalosis
What are the main Gastrointestinal changes in Anorexia nervosa and how are they monitored and managed acutely?
Changes: Acute pancreatitis Parotid and salivary gland hypertrophy Reduced gastric motility Oesophagitis / ulceration / strictures Mallory-weiss tears Gastric rupture Diarrhoea Raised liver enzymes Low albumin
Monitoring:
Physical exam (gastro)
LFT (AST &ALP) + Lipase
Acute management:
Surgical referral for complications
Bowel rest, NG suction, and fluid replacement for pancreatitis
What is the main Haematological change in Anorexia nervosa and how is it monitored and managed acutely?
Change:
Anaemia
Monitoring:
FBE +/- Iron studies
B12
Folate
Management:
Oral replacement therapies
What is the main Body Temperature change in Anorexia nervosa and how is it monitored and managed acutely?
Change:
Hypothermia
Monitoring:
Repeated temperature measurement
Observe for signs of infection as hypothermia can mask pyrexia
What are the main Immune function changes in Anorexia nervosa and how are they monitored and managed acutely?
Change:
Low white cell count
Susceptibility to bacterial infections
Monitor:
FBE
Monitor for signs of infection
What are the main Cardiovascular changes in Anorexia nervosa and how are they monitored and managed acutely?
Changes:
Bradycardia and hypotension
Arrhythmias
Cardiomyopathy (Ipecac (emetic) use)
Monitoring:
ECG (always)
CXR
Treatment:
Symptomatic oedema treatment
Treatment of arrhythmia
What are the main Renal changes in Anorexia nervosa and how are they monitored and managed acutely?
Changes: Elevated UEC (increased muscle catabolism) Hypokalaemic nephropathy Reduced serum creatinine High ketones Polyuria
Monitoring:
UEC
Treatment:
If needed, specialist referral