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Psych matrix > Antipsychotic medications > Flashcards

Antipsychotic medications Flashcards

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1
Q

Is Amisulpride (solian, solprix) a typical or atypical antipsychotic?

A

Atypical

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2
Q

Is Aripiprazole (abilify) a typical or atypical antipsychotic?

A

Atypical

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3
Q

Is Asenapine (Saphris) a typical or atypical antipsychotic?

A

Atypical

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4
Q

Is Brexpriprazole (rexulti) a typical or atypical antipsychotic?

A

Atypical

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5
Q

is Chlorpromazine (largactil) a typical or atypical antipsychotic?

A

Typical

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6
Q

Is Clozapine (Clopine) a typical or atypical antipsychotic?

A

Atypical

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7
Q

Is Flupentixol (bentovate) a typical or atypical antipsychotic?

A

Typical

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8
Q

Is Haloperidol (serenace) a typical or atypical antipsychotic?

A

Typical

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9
Q

Is Lurasidone (Ardix lurasidone, latuda, lurasidone lupin) a typical or atypical antipsychotic?

A

Atypical

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10
Q

Is Olanzapine (pyrex) a typical or atypical antipsychotic?

A

Atypical

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11
Q

Is Paliperidone (invega) a typical or atypical antipsychotic?

A

Atypical

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12
Q

Is periciazine (neulactil) a typical or atypical antipsychotic?

A

Typical

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13
Q

Is Quetiapine (seroquel, quetia, quepine, tevatiapine) a typical or atypical antipsychotic?

A

Atypical

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14
Q

Is Risperidone (risperidal) a typical or atypical antipsychotic?

A

Atypical

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15
Q

Is Ziprasidone (Ziprox, Zeldox) a typical or atypical antipsychotic?

A

Atypical

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16
Q

Is Zuclopenthixol (clopixol) a typical or atypical antipsychotic?

A

Typical

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17
Q

In schizophrenia, what is the oral dosage of Amisulpride (solian, solprix)?

A

100mg at night initially

Increasing to 200mg twice daily

Maximum dose is 1200mg per day

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18
Q

In schizophrenia, what is the oral dosage of Aripiprazole (abilify)?

A

10mg once daily initially

Increase to 15mg once daily

Maximum dosage is 30mg per day

19
Q

In schizophrenia, what is the oral dosage of Olanzapine (pyrex)?

A

5mg at night initially

Increase to 10mg at night

Maximum dose is 30mg per day

20
Q

In schizophrenia, what is the oral dosage of Paliperidone (invega)?

A

3mg orally at night

Increase to 6mg at night

Maximum dose is 12mg per day

Adjust dose in renal impairment patients

21
Q

In schizophrenia, what is the oral dosage of Quetiapine (seroquel, quetia, quepine, tevatiapine)?

A

50mg twice daily on day 1

100mg twice daily on day 2

Increasing to 200mg twice daily (response usually seen in higher dosages)

Maximum dosage is 800mg per day

22
Q

In schizophrenia, what is the oral dosage of Risperidone (risperidal)?

A

0.5-1mg at night initially

Increase to 2mg at night

Maximum dose is 6mg

23
Q

In schizophrenia, what is the oral dosage of Ziprasidone (Ziprox, Zeldox)?

A

40mg twice daily with food

Maximum dosage 80mg

24
Q

In schizophrenia, what is the oral dosage of Asenapine (Saphris)?

A

5mg sublingually twice per day, before food.

Maximum dosage is 10mg

25
Q

In schizophrenia, what is the oral dosage of Chlorpromazine (largactil)?

A

200mg at night initially

Staged increase to maximum of 800mg

26
Q

In schizophrenia, what is the oral dosage of Haloperidol (serenace)?

A

1.5mg at night

Staged increase to a maximum of 10mg

27
Q

In schizophrenia, what is the oral dosage of periciazine (neulactil)?

A

10mg at night

Staged increase to a maximum of 75mg in staged doses

28
Q

In schizophrenia, what is the depot dosage of Flupentoxol (bentovate)?

A

10mg, titrated up to 20-40 mg every 2-4 weeks

29
Q

In schizophrenia, what is the depot dosage of Haloperidol (serenace)?

A

50mg initially, titrated to 50-200mg every 4 weeks

30
Q

In schizophrenia, what is the depot dosage of Paliperidone (invega)?

A

150mg followed by 100mg one week later (loading dose)

75mg every 4 weeks after

Can be titrated between 50-150mg

31
Q

In schizophrenia, what is the depot dosage of Risperidone (risperidal)?

A

25mg initially

Titrate to 25-50mg every 2 weeks

+++Drug not released for 3 weeks, needs bridging antipsychotics

32
Q

In schizophrenia, what is the depot dosage of Zuclopenthixol (clopixol)?

A

100mg initially

titrated to 200-400mg every 2-4 weeks

33
Q

In schizophrenia, what is the depot dosage of Olanzapine (pyrex)?

A

210mg every 2 weeks or 405mg every 4 weeks as a loading dose

Then 150mg every 2 weeks or 300mg every 4 weeks thereafter

Maximum is 300mg every 2 weeks

34
Q

What is the general MOA of antipsychotics?

A

D2 receptor blockade (all)

D1 blockade (some)

Blockade of 5HT2 receptor (some)

35
Q

Indications for antipsychotics

A

Acute psychosis
Chronic psychosis
Maintenance therapy for schizophrenia
Bipolar

36
Q

Which antipsychotics cause respiratory depression?

A

Chlorpromazine
Clozapine
Olanzapine
Periciazine

37
Q

What general considerations should be taken into account before starting antipsychotics?

A

Hyperthyroidism (increases dystonia risk)
Temperature regulation (antipsychotics further alter this)
Hypotension (drugs can exacerbate this)
GI obstruction
Urinary obstruction (anticholinergic effects of some drugs can worsen this)
Low white cell count or previous blood dyscrasia
Diabetes (drugs increase blood glucose)
Prolactinoma (increased growth)

38
Q

Which antipsychotics increase the QT interval

A

Amisulpride
Droperidol
Haloperidol
Ziprasidone

39
Q

Which antipsychotic drugs most commonly cause extrapyramidal side effects?

A

Haloperidol and trifluoperazine

But all can at higher dosages

40
Q

What is the treatment for drug induced acute dystonia?

A

Benzatropine 1-2mg IM or IV

41
Q

What antipsychotic drug is most associated with skin reactions?

A

Chlorpromazine - photosensitivity, phototoxicity, hyperpigmentation

42
Q

What are the 5 commonly used TYPICAL antipsychotics?

A 
Chlorpromazine (largactil)
Periciazine (neulactil)
Flupentixol (bentovate)
Zulcopenthioxol (clopixol)
Haloperidol (serenace)
43
Q

What are What are the 11 commonly used ATYPICAL antipsychotics?

A 
Amisulpride (solian, sulprix)
Aripiprazole (abilify)
Brexpiprazole (rexulti)
Risperidone (resperidal)
Ziprasidone (Ziprox, Zeldox)
Lurasidone (ardix, latuda, lupin)
Paliperidone (invega)
Asenapine (saphris)
Clozapine (clopine)
Olanzapine (pyrex)
Quetiapine (seroquel, quetia, quepine, tevatiapine)

Psych matrix (49 decks)

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