Fecondation Flashcards

1
Q

def de la fecondation

A

fusion de 2 gametes haploides en 1 c di;oide appelee zygote

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2
Q

interaction gametique

A

yes dialogue

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3
Q

2 gametes similaires

A

non tres diff

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4
Q

m qte de cyto spz et ovo

A

non

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5
Q

taille spz vs ovo:

A

60microns vs 120microns

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6
Q

spz vs ovo: m type ADN

A

non protamines et ponts S-S

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7
Q

duree de survie des spz

A

3-4j

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8
Q

duree de survie de ovoycte : 3-4j

A

non 10-24h

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9
Q

periode de fecondabilite ne depasse pas 3 j

A

non c’est 5j

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10
Q

ovo: duree stay in ampoule 10h

A

non 72 h

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11
Q

ct transport de ovo ds trompes

A

cell msucles lisses + cils

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12
Q

act contractile de trompes sous dpd des hormones

A

yes progesterone ralentit cnotraction

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13
Q

5 ffonctions du trajet du spz (*****)

A
  1. elimier liquide seminal
  2. filtrer LEUCO bact elimier spz morts immatures
  3. seection selon mobilite et morpho
  4. controler nb de spz
  5. gamaciter les gametes
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14
Q

qui est premier lieu de stockage

A

crytpes des GLANDES endo cervicales

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15
Q

struc de la glaire cervi et type de liaison

A

glycoprot avec S-S

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16
Q

en phase pre ovu gl ceviale = 3-4 microns

A

non 30microns

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17
Q

en phase pre ovu gl ceviale = mailles fines

A

non LARGES

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18
Q

gl cervi tjs permeable aux spz

A

non pas en post ovu

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19
Q

m qte de gl pdt tout le cycle

A

non moins en post ovu

20
Q

spz in uterus ds les secondes apres coit

A

non ds les MINUTES (doivent oasser la gl cervicale)

21
Q

role dusphincter uetro tubaire

A

controler acces aux trompes

22
Q

ou 2e lieu de stoclage

A

isthme tubaire

23
Q

pq ralentissement isthme tubaire

A

oedome - viscocite - l temporaire des spz aux epi

24
Q

les spz trvaersnet ampoule

A

yes –> cul de sac de Douglas

25
Q

pq spz attires par ampoule

A

mol chimio attractives - contractions - cils

26
Q

spz ejacule in vivo est fecondant (5/5)

A

non car pas encore capacite

27
Q

capacitation: in vajayjay

A

non que uterus et trompes

28
Q

capacitation: dpd de shormones

A

yes

29
Q

in vivo capacitation: dpd de q hormone

A

oestro

30
Q

capacitation: in vitro : oestro

A

non PROGES- liquie FOLL

31
Q

capacitation: irreversible et d’un coup

A

non reversible et progressive

32
Q

in vitro capacitation: lente

A

non rapide

33
Q

tous les spz achevent leur capacitation ensemble

A

non par gr heterogenes

34
Q

act adenylate cyclase : hydrolyse ATP

A

yes (AMPc)

35
Q

capacitation stabilise la MP

A

non destabilise

36
Q

4 conse de capacitation

A
  1. demasquage de srecept spermati 2. mobilisiation des prot 3. permeabilite au Ca2+ 3. hyper activation du mvt
37
Q

capacitation : hyperactivation de prot d ela region acrosmo

A

non de la region PERI acrosomique

38
Q

3 modifs de la MP pdt capacitation

A

ELiminer 1. prot de revetement

  1. cholesterol libre
  2. residus glucidiques
39
Q

pq enlever cholesterol

A

–> fluidifier MP ==> permeabilite au CA2+ ==>

40
Q

y a PE ds MP de spz capacite

A

non car Ca2+ se lie a PS –> PS ne liue plus Pe

41
Q

PE forme des micelles fluidifiant la membrane instavle

A

yes

42
Q

QUI acteurs de la capacitation

A

albumine - heparine et chondroitine sulfate acidite du PH uterin lipoprot

43
Q

acidite du PH vaginal enleve les prot de revet

A

non capciation QUE ds uterus et trompes

44
Q

capacitaiton : remaniement des chaines oligosacchariques de struc

A

yes

45
Q

role des prot de rvetemn

A

proteection pdt trajet d epidydyme