Fatty Acid Synthesis - Pathway

Question 1

Acetyl CoA + _____ + ATP + _____ (E) → _____ + _____ + ADP + P_i

Answer 1

Acetyl CoA + HCO₃^- + ATP + acetyl CoA carboxylase (E) → malonyl CoA + H+ + ADP + P_i

Question 2

Acetyl CoA + ACP + _____ (E) ⇔ _____ + _____

Answer 2

Acetyl CoA + ACP + acetyl transacylase (E) ⇔ acetyl ACP + CoA

Question 3

Malonyl CoA + _____ + _____ (E) ⇔ _____ + _____

Answer 3

Malonyl CoA + ACP + malonyl transacylase (E) ⇔ malonyl ACP + CoA

Question 4

Malonyl ACP + acetyl ACP + _____ (E) → _____ + _____ + _____

Answer 4

Malonyl ACP + acetyl ACP + beta-ketoacyl synthase (E) → acetoacyl ACP + ACP + CO₂

Question 5

Acetoacyl ACP + _____ + _____ + _____ (E) ⇔ _____ + _____

Answer 5

Acetoacyl ACP + NADPH + H+ + beta-ketoacyl reductase (E) ⇔ D-3-hydroxybutyryl ACP + NADP+

Question 6

D-hydroxybutyryl ACP + _____ (E) ⇔ _____ + _____

Answer 6

D-hydroxybutyryl ACP + 3-hydroacyl dehydratase (E) ⇔ crotonyl ACP + H₂O

Question 7

Crotonyl ACP + _____ + _____ + _____ (E) → _____ + _____

Answer 7

Crotonyl ACP + NADPH + H+ + enoyl reductase (E) → buturyl ACP + NADP+