Fatty acid oxidation

Question 1

how much energy for the body comes from triglycerides

Answer 1

1/3

Question 2

triglycerides meet __% of energy needs of heart and liver

Answer 2

80

Question 3

waht do muscles use for enregy

Answer 3

fats (esp preferred for resting)

Question 4

describe mobilisation of triglycerides

Answer 4

• glucagon and adrenaline attach
• lipase breaks down to triglycerides
• goes via serum albumin to target cells

Question 5

describe digestion of triglycerides

Answer 5

bile salts emulsify fat droplets - increasing SA
intracellular lipase converts to glycerol and fa’s
sometimes can be stored as micelles or diffuse through epithelial cells
otherwise, goes to smooth er where it is reformed to gtriglyceride. then goes to golgi, where its packaged and modified to a chylomicron. Then the chylomicron goes through lacteal to blood vessels.

Question 6

fate of glycerol

Answer 6

can be oxidised isomerised and phosphorylated to form glyceraldehyde-3-phosphate to enter glycolysis
5% of energy of triglycerides

Question 7

how does fatty acyl CoA pass the mito membs

Answer 7

fatty acyl coa + carnitine –> fatty acyl carnitine + COASH
FAC crosses carnitine acyl transferase and acyl carnitine/carnitine transporter and then goes to matrix; carnitine goes back to outer mito memb

Question 8

how are mono and polyunsatruated fa’s done

Answer 8

with isomerase, and isomerase and transferase

Question 9

fates of acetyl coa

Answer 9

goes into CAC or if oxaloacetate conc is low in liver, acetyl co a is pushed towards ketone body formation and not cac