Fatty Acid Breakdown

Question 1

how are triacylglycerols moved from the adipocyte cells and into the myocyte cells

Answer 1

1) Glucagon binds to a receptor that activates a G protein
2) G protein makes Adenyl cyclase convert ATP to cAMP
3) cAMP activates PKA which phosphorylates the hormone sensitive lipase and the perilipins on the lipid droplet
4) the lipase hydrolyzes the triacylglycerols to free fatty acids which bind to serum albumin in the blood, a fatty acid transporter brings them into the myocyte

4)

Question 2

over view of fat transport into storage

Answer 2

1) bile emulsifies
2) intestinal lipases degrade triacylgylcerols
3) intestinal mucosa takes up the break down products and converts everything into triacylglycerols
4) triacylgylcerols are incorporated with cholesterol and apolipoproteins into chylomicrons which move through the lymphatic system and blood stream into tissues
5) Lipoprotein lipase, activated by apoC-II converts triacylglycerols to fatty acids and glycerol which enter the cells and can be broken down or reesterified