Fat Pharm Flashcards
1
Q
Phentermine- MOA
A
Increases release of norepi & dopamine, inhibits reuptake
2
Q
Phentermine- Indications
A
Anorexiant- short term obesity management
3
Q
Phentermine- AE
A
- Dry mouth, HA, insomnia
- HR, BP, heart valve disorders
4
Q
Orlistat- MOA
A
Lipase inhibitor- inhibits breakdown of fat into absorpable molecules
5
Q
Orlistat- Indications
A
- Anti-obesity, in conjunction with low fat diet to limit fat intake
6
Q
Orlistat- AE
A
- Oily flatuance, fecal urgency, increased deification
- Malabsorption of fat soluble vitamins
7
Q
Lorcaserin- MOA
A
- Promotes satiety
- Selective serotonin agonist
8
Q
Lorcaserin- Indications
A
Long term obesity tx
9
Q
Lorcaserin- AE
A
- Hypoglycemia, HA, URI, lymphopnea
- Serotonin syndrome, valvular heart disease, pulm HTN
10
Q
Qsymia- MOA
A
- Topiramate: Augments GABA activity, antagonizes glutamate receptors
- Phentermine: Increases release of norepi & dopamine, inhibits reuptake
11
Q
Qsymia- Indications
A
-New med combining antiseizure and anorexic for wt loss
12
Q
Qsymia- AE
A
- Paresthesia, xerostoma, constipation
- Glaucoma, renal stones, metabolic acidosis
